Induction of Apoptosis in Small-Cell Lung Cancer Cells by an Antisense Oligodeoxynucleotide Targeting the Bcl-2 Coding Sequence
Ziegler, Annemarie, Luedke, Gerd H., Stahel, Rolf A., Zangemeister-Wittke, Uwe, Fabbro, Doriano, Altmann, Karl-Heinz
Published in JNCI : Journal of the National Cancer Institute (16.07.1997)
Published in JNCI : Journal of the National Cancer Institute (16.07.1997)
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Journal Article
Patupilone (epothilone B, ep0906) and imatinib (STI571, Glivec) in combination display enhanced antitumour activity in vivo against experimental rat C6 glioma
O'REILLY, T, WARTMANN, M, MAIRA, S.-M, HATTENBERGER, M, VAXELAIRE, J, MULLER, M, FERRETTI, S, BUCHDUNGER, E, ALTMANN, K.-H, MCSHEEHY, P. M. J
Published in Cancer chemotherapy and pharmacology (01.04.2005)
Published in Cancer chemotherapy and pharmacology (01.04.2005)
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Journal Article
Chemical Synthesis and Biological Evaluation of cis- and trans-12,13-Cyclopropyl and 12,13-Cyclobutyl Epothilones and Related Pyridine Side Chain Analogues
Nicolaou, K. C, Namoto, Kenji, Ritzén, Andreas, Ulven, Trond, Shoji, Mitsuru, Li, Jim, D'Amico, Gina, Liotta, Dennis, French, Christopher T, Wartmann, Markus, Altmann, Karl-Heinz, Giannakakou, Paraskevi
Published in Journal of the American Chemical Society (26.09.2001)
Published in Journal of the American Chemical Society (26.09.2001)
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Journal Article
Macrolide-based microtubule-stabilizing agents - chemistry and structure-activity relationships
Pfeiffer, B, Kuzniewski, C N, Wullschleger, C, Altmann, K-H
Published in Topics in current chemistry (01.01.2009)
Published in Topics in current chemistry (01.01.2009)
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Journal Article
Second-generation antisense oligonucleotides: structure-activity relationships and the design of improved signal-transduction inhibitors
Altmann, K H, Fabbro, D, Dean, N M, Geiger, T, Monia, B P, Müller, M, Nicklin, P
Published in Biochemical Society transactions (01.08.1996)
Published in Biochemical Society transactions (01.08.1996)
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Journal Article
Backbone modifications in oligonucleotides and peptide nucleic acid systems
De Mesmaeker, Alain, Altmann, Karl-Heinz, Waldner, Adrian, Wendeborn, Sebastian
Published in Current opinion in structural biology (01.06.1995)
Published in Current opinion in structural biology (01.06.1995)
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Journal Article
Sequence-Specific Antitumor Activity of a Phosphorothioate Oligodeoxyribonucleotide Targeted to Human C-Raf Kinase Supports an Antisense Mechanism of Action in vivo
Monia, Brett P., Sasmor, Henri, Johnston, Joseph F., Freier, Susan M., Lesnik, Elena A., Muller, Marcel, Geiger, Thomas, Altmann, Karl-Heinz, Moser, Heinz, Fabbro, Doriano
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (24.12.1996)
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Journal Article
Microtubule-stabilizing agents: a growing class of important anticancer drugs
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Book Review
Journal Article
Epothilones and related structures – a new class of microtubule inhibitors with potent in vivo antitumor activity
Altmann, Karl-Heinz, Wartmann, Markus, O’Reilly, Terence
Published in BBA - Reviews on Cancer (17.05.2000)
Published in BBA - Reviews on Cancer (17.05.2000)
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Book Review
Journal Article
STUDIES OF A CHEMICALLY MODIFIED OLIGODEOXYNUCLEOTIDE CONTAINING A 5-ATOM AMIDE BACKBONE WHICH EXHIBITS IMPROVED BINDING TO RNA
Wilds, Christopher J., Minasov, George, Natt, François, von Matt, Peter, Altmann, Karl-Heinz, Egli, Martin
Published in Nucleosides, nucleotides & nucleic acids (01.04.2001)
Published in Nucleosides, nucleotides & nucleic acids (01.04.2001)
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Journal Article
New Anilinophthalazines as Potent and Orally Well Absorbed Inhibitors of the VEGF Receptor Tyrosine Kinases Useful as Antagonists of Tumor-Driven Angiogenesis
Bold, Guido, Altmann, Karl-Heinz, Frei, Jörg, Lang, Marc, Manley, Paul W, Traxler, Peter, Wietfeld, Bernhard, Brüggen, Josef, Buchdunger, Elisabeth, Cozens, Robert, Ferrari, Stefano, Furet, Pascal, Hofmann, Francesco, Martiny-Baron, Georg, Mestan, Jürgen, Rösel, Johannes, Sills, Matthew, Stover, David, Acemoglu, Figan, Boss, Eugen, Emmenegger, René, Lässer, Laurent, Masso, Elvira, Roth, Rosemarie, Schlachter, Christian, Vetterli, Werner, Wyss, Dominique, Wood, Jeanette M
Published in Journal of medicinal chemistry (15.06.2000)
Published in Journal of medicinal chemistry (15.06.2000)
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Journal Article
Resorcylic Acid Lactone L-783,277 Inhibits the Growth of the Human Adrenal Cancer Cell Line H295R in Vitro
Lawnicka, H., Kowalewicz-Kulbat, M., Sicinska, P., Altmann, K.H., Hofmann, T., Stepien, H.
Published in International journal of immunopathology and pharmacology (01.10.2009)
Published in International journal of immunopathology and pharmacology (01.10.2009)
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Journal Article
The Solution Conformation of a Carbocyclic Analog of the Dickerson-Drew Dodecamer: Comparison with its own X-ray Structure and that of the NMR Structure of the Native Counterpart
Denisov, Aleksej Yu, Zamaratski, E. V., Maltseva, Tatiana V., Sandström, Anders, Bekiroglu, Somer, Altmann, Karl-Heinz, Egli, Martin, Chattopadhyaya, Jyoti
Published in Journal of biomolecular structure & dynamics (01.12.1998)
Published in Journal of biomolecular structure & dynamics (01.12.1998)
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Journal Article
Chemical synthesis and biological properties of pyridine epothilones
Nicolaou, KC, Scarpelli, R, Bollbuck, B, Werschkun, B, Pereira, MMA, Wartmann, M, Altmann, K-H, Zaharevitz, D, Gussio, R, Giannakakou, P
Published in Chemistry & biology (01.08.2000)
Published in Chemistry & biology (01.08.2000)
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Journal Article