U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication
DUEWEKE, T. J, POPPE, S. M, MAYERS, D. L, LANE, J, ARISTOFF, P. A, THOMAS, R. C, TARPLEY, W. G, ROMERO, D. L, SWANEY, S. M, SO, A. G, DOWNEY, K. M, ALTHAUS, I. W, REUSSER, F, BUSSO, M, RESNICK, L
Published in Antimicrobial Agents and Chemotherapy (01.05.1993)
Published in Antimicrobial Agents and Chemotherapy (01.05.1993)
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The quinoline U-78036 is a potent inhibitor of HIV-1 reverse transcriptase
ALTHAUS, I. W, GONZALES, A. J, DOWNEY, K. M, THOMAS, R. C, ARISTOFF, P. A, TARPLEY, W. G, REUSSER, F, CHOU, J. J, ROMERO, D. L, DEIBEL, M. R, KUO-CHEN CHOU, KEZDY, F. J, RESNICK, L, BUSSO, M. E, SO, A. G
Published in The Journal of biological chemistry (15.07.1993)
Published in The Journal of biological chemistry (15.07.1993)
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The benzylthio-pyrimidine U-31,355, a potent inhibitor of HIV-1 reverse transcriptase
Althaus, Irene W., Chou, Kuo-Chen, Lemay, Richelle J., Franks, Kellie M., Deibel, Martin R., Kezdy, Ferenc J., Resnick, Lionel, Busso, Mariano E., So, Antero G., Downey, Kathleen M., Romero, Donna L., Thomas, Richard C., Aristoff, Paul A., Tarpley, W.Gary, Reusser, Fritz
Published in Biochemical pharmacology (22.03.1996)
Published in Biochemical pharmacology (22.03.1996)
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Steady-state kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-87201E
Althaus, I W, Chou, J J, Gonzales, A J, Deibel, M R, Chou, K C, Kezdy, F J, Romero, D L, Aristoff, P A, Tarpley, W G, Reusser, F
Published in The Journal of biological chemistry (25.03.1993)
Published in The Journal of biological chemistry (25.03.1993)
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The amphiphilic properties of novenamines determine their activity as inhibitors of HIV-1 RNase H
Althaus, I W, Franks, K M, Langley, K B, Kézdy, F J, Peterson, T, Buxser, S E, Decker, D E, Dolak, L A, Ulrich, R G, Reusser, F
Published in Experientia (15.04.1996)
Published in Experientia (15.04.1996)
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Kinetic studies with the non-nucleoside HIV-1 reverse transcriptase inhibitor U-88204E
Althaus, Irene W, Chou, James J, Gonzales, Andrea J, Deibel, Martin R, Chou, Kuo Chen, Kezdy, Ferenc J, Romero, Donna L, Palmer, John R, Thomas, Richard C
Published in Biochemistry (Easton) (01.07.1993)
Published in Biochemistry (Easton) (01.07.1993)
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Steady-state kinetic studies with the polysulfonate U-9843, an HIV reverse transcriptase inhibitor
Althaus, I W, Chou, J J, Gonzales, A J, LeMay, R J, Deibel, M R, Chou, K C, Kezdy, F J, Romero, D L, Thomas, R C, Aristoff, P A
Published in Experientia (15.01.1994)
Published in Experientia (15.01.1994)
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BIS(HETEROARYL)PIPERAZINE (BHAP) REVERSE-TRANSCRIPTASE INHIBITORS - STRUCTURE-ACTIVITY-RELATIONSHIPS OF NOVEL SUBSTITUTED INDOLE ANALOGS AND THE IDENTIFICATION OF 1-[(5-METHANESULFONAMIDO-1H-INDOL-2-YL)-CARBONYL]-4-[3-[(1-METHYLETHYL)AMINO]-PYRIDINYL]PIPERAZINE MONOMETHANESULFONATE (U-90152S), A 2ND-GENERATION CLINICAL CANDIDATE
ROMERO, DL, MORGE, RA, GENIN, MJ, BILES, C, BUSSO, M, RESNICK, L, ALTHAUS, IW, REUSSER, F, THOMAS, RC, TARPLEY, WG
Published in Journal of medicinal chemistry (14.05.1993)
Published in Journal of medicinal chemistry (14.05.1993)
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Kinetic studies with the non-nucleoside human immunodeficiency virus type-1 reverse transcriptase inhibitor U-90152E
Althaus, Irene W., Chou, James J., Gonzales, Andrea J., Deibel, Martin R., Kuo-Chen, Chou, Kezdy, Ferenc J., Romero, Donna L., Thomas, Richard C., Aristoff, Paul A., Tarpley, W.Gary, Reusser, Fritz
Published in Biochemical pharmacology (01.06.1994)
Published in Biochemical pharmacology (01.06.1994)
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Enzymatic kinetic studies with the non-nucleoside HIV reverse transcriptase inhibitor U-9843
Althaus, I W, LeMay, R J, Gonzales, A J, Deibel, M R, Sharma, S K, Kezdy, F J, Resnick, L, Busso, M E, Aristoff, P A, Reusser, F
Published in Experientia (01.12.1992)
Published in Experientia (01.12.1992)
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Discovery, Synthesis, and Bioactivity of Bis(heteroaryl)piperazines. 1. A Novel Class of Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors
Romero, Donna L, Morge, Raymond A, Biles, Carolyn, Berrios-Pena, Norman, May, Paul D, Palmer, John R, Johnson, Paul D, Smith, Herman W, Busso, Mariano, et. al
Published in Journal of medicinal chemistry (01.04.1994)
Published in Journal of medicinal chemistry (01.04.1994)
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Tyrosine Kinase Inhibitors. 19. 6-Alkynamides of 4-Anilinoquinazolines and 4-Anilinopyrido[3,4-d]pyrimidines as Irreversible Inhibitors of the erbB Family of Tyrosine Kinase Receptors
Klutchko, Sylvester R, Zhou, Hairong, Winters, R. Thomas, Tran, Tuan P, Bridges, Alexander J, Althaus, Irene W, Amato, Danielle M, Elliott, William L, Ellis, Paul A, Meade, Mary Ann, Roberts, Billy J, Fry, David W, Gonzales, Andrea J, Harvey, Patricia J, Nelson, James M, Sherwood, Veronica, Han, Hyo-Kyung, Pace, Gerry, Smaill, Jeff B, Denny, William A, Showalter, H. D. Hollis
Published in Journal of medicinal chemistry (23.02.2006)
Published in Journal of medicinal chemistry (23.02.2006)
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DISCOVERY, SYNTHESIS, AND BIOACTIVITY OF BIS(HETEROARYL)PIPERAZINES .1. A NOVEL CLASS OF NONNUCLEOSIDE HIV-1 REVERSE-TRANSCRIPTASE INHIBITORS
ROMERO, DL, MORGE, RA, BILES, C, BERRIOSPENA, TN, MAY, PD, PALMER, JOHNSON, PD, SMITH, HW, BUSSO, M, TAN, CK, VOORMAN, RL, REUSSER, F, ALTHAUS, IW, DOWNEY, KM, SO, AG, RESNICK, L, TARPLEY, WG, ARISTOFF, PA
Published in Journal of medicinal chemistry (01.04.1994)
Published in Journal of medicinal chemistry (01.04.1994)
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Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhitors : structure-activity relationships of novel substituted indole analogues and the identification of 1-[(5-methanesulfonamido-1-H-indol-2-yl)-carbonyl]-4-[3-[(1-methylethyl)amino]-pyridinyl]piperazine monomethanesulfonate (U-90152S), a second-generation clinical candidate
ROMERO, D. L, MORGE, R. A, GENIN, M. J, BILES, C, BUSSO, M, RESNICK, L, ALTHAUS, I. W, REUSSER, F, THOMAS, R. C, TARPLEY, W. G
Published in Journal of medicinal chemistry (1993)
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Published in Journal of medicinal chemistry (1993)
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Bis(heteroaryl)piperazine (BHAP) reverse transcriptase inhibitors: Structure-activity relationships of novel substituted indole analogues and the identification of 1-((5-methanesulfonamido-1H-indol-2-yl)-carbonyl)-4-(3-((1-methyle thyl)amino)-pyridinyl)piperazine monomethanesulfonate (U-90152S), a second-generation clinical candidate
Romero, D L, Morge, R A, Genin, MJ, Biles, C, Busso, M, Resnick, L, Althaus, I W, Reusser, F, Thomas, R C, Tarpley, W G
Published in Journal of medicinal chemistry (01.01.1993)
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Published in Journal of medicinal chemistry (01.01.1993)
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Steady-state kinetic studies with the non-nucleotide HIV-1 reverse transcriptase inhibitor U-8720E
ALTHAUS, I. W, CHOU, J. J, GONZALES, A. J, DEIBEL, M. R, KUO-CHEN CHOU, KEZDY, F. J, ROMERO, D. L, ARISTOFF, P. A, TARPLEY, W. G, REUSSER, F
Published in The Journal of biological chemistry (1993)
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Published in The Journal of biological chemistry (1993)
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Discovery, synthesis, and bioactivity of bis(heteroaryl)piperazines. I: A novel class of non-nucleoside HIV-1 reverse transcriptase inhibitors
ROMERO, D. L, MORGE, R. A, VOORMAN, R. L, REUSSER, F, ALTHAUS, I. W, DOWNEY, K. M, SO, A. G, RESNICK, L, TARPLEY, W. G, ARISTOFF, P. A, BILES, C, BERRIOS-PENA, N, MAY, P. D, PALMER, J. R, JOHNSON, P. D, SMITH, H. W, BUSSO, M, CHENG-KEAT TAN
Published in Journal of medicinal chemistry (1994)
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Published in Journal of medicinal chemistry (1994)
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