Moderation of iodoacetate-induced experimental osteoarthritis in rats by matrix metalloproteinase inhibitors
Janusz, M.J., Hookfin, E.B., Heitmeyer, S.A., Woessner, J.F., Freemont, A.J., Hoyland, J.A., Brown, K.K., Hsieh, L.C., Almstead, N.G., De, B., Natchus, M.G., Pikul, S., Taiwo, Y.O.
Published in Osteoarthritis and cartilage (01.11.2001)
Published in Osteoarthritis and cartilage (01.11.2001)
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Journal Article
Discovery of Potent, Achiral Matrix Metalloproteinase Inhibitors
Pikul, Stanislaw, McDow Dunham, Kelly L, Almstead, Neil G, De, Biswanath, Natchus, Michael G, Anastasio, Melanie V, McPhail, Sara J, Snider, Catherine E, Taiwo, Yetunde O, Rydel, Timothy, Dunaway, C. Michelle, Gu, Fei, Mieling, Glen E
Published in Journal of medicinal chemistry (10.09.1998)
Published in Journal of medicinal chemistry (10.09.1998)
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Journal Article
Design and Synthesis of Piperazine-Based Matrix Metalloproteinase Inhibitors
Cheng, Menyan, De, Biswanath, Pikul, Stanislaw, Almstead, Neil G, Natchus, Michael G, Anastasio, Melanie V, McPhail, Sara J, Snider, Catherine E, Taiwo, Yetunde O, Chen, Longyin, Dunaway, C. Michelle, Gu, Fei, Dowty, Martin E, Mieling, Glen E, Janusz, Michael J, Wang-Weigand, Sherry
Published in Journal of medicinal chemistry (10.02.2000)
Published in Journal of medicinal chemistry (10.02.2000)
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Journal Article
Design, Synthesis, and Biological Evaluation of Potent Thiazine- and Thiazepine-Based Matrix Metalloproteinase Inhibitors
Almstead, Neil G, Bradley, Rimma S, Pikul, Stanislaw, De, Biswanath, Natchus, Michael G, Taiwo, Yetunde O, Gu, Fei, Williams, Lisa E, Hynd, Barbara A, Janusz, Michael J, Dunaway, C. Michelle, Mieling, Glen E
Published in Journal of medicinal chemistry (04.11.1999)
Published in Journal of medicinal chemistry (04.11.1999)
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Journal Article
Potent and Selective Carboxylic Acid-Based Inhibitors of Matrix Metalloproteinases
Pikul, Stanislaw, Ohler, Norman E, Ciszewski, Greg, Laufersweiler, Michael C, Almstead, Neil G, De, Biswanath, Natchus, Michael G, Hsieh, Lily C, Janusz, Michael J, Peng, Sean X, Branch, Todd M, King, Selane L, Taiwo, Yetunde O, Mieling, Glen E
Published in Journal of medicinal chemistry (02.08.2001)
Published in Journal of medicinal chemistry (02.08.2001)
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Journal Article
Design and Synthesis of Phosphinamide-Based Hydroxamic Acids as Inhibitors of Matrix Metalloproteinases
Pikul, Stanislaw, McDow Dunham, Kelly L, Almstead, Neil G, De, Biswanath, Natchus, Michael G, Anastasio, Melanie V, McPhail, Sara J, Snider, Catherine E, Taiwo, Yetunde O, Chen, Longyin, Dunaway, C. Michelle, Gu, Fei, Mieling, Glen E
Published in Journal of medicinal chemistry (14.01.1999)
Published in Journal of medicinal chemistry (14.01.1999)
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Journal Article
Design, Synthesis, and Biological Evaluation of Matrix Metalloproteinase Inhibitors Derived from a Modified Proline Scaffold
Cheng, Menyan, De, Biswanath, Almstead, Neil G, Pikul, Stanislaw, Dowty, Martin E, Dietsch, Charles R, Dunaway, C. Michelle, Gu, Fei, Hsieh, Lily C, Janusz, Michael J, Taiwo, Yetunde O, Natchus, Michael G, Hudlicky, Tomas, Mandel, Martin
Published in Journal of medicinal chemistry (30.12.1999)
Published in Journal of medicinal chemistry (30.12.1999)
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Journal Article
Design and synthesis of conformationally-constrained MMP inhibitors
Natchus, Michael G., Cheng, Menyan, Wahl, Christopher T., Pikul, Stanislaw, Almstead, Neil G., Bradley, Rimma S., Taiwo, Yetunde O., Mieling, Glen E., Dunaway, C.Michelle, Snider, Catherine E., McIver, John M., Barnett, Bobby L., McPhail, Sara J., Anastasio, Melanie B., De, Biswanath
Published in Bioorganic & medicinal chemistry letters (18.08.1998)
Published in Bioorganic & medicinal chemistry letters (18.08.1998)
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Journal Article
Comparison of the pharmacology of hydroxamate- and carboxylate-based matrix metalloproteinase inhibitors (MMPIs) for the treatment of osteoarthritis
Janusz, M J, Hookfin, E B, Brown, K K, Hsieh, L C, Heitmeyer, S A, Taiwo, Y O, Natchus, M G, Pikul, S, Almstead, N G, De, B, Peng, S X, Baker, T R, Patel, V
Published in Inflammation research (01.02.2006)
Published in Inflammation research (01.02.2006)
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Journal Article
Development of New Hydroxamate Matrix Metalloproteinase Inhibitors Derived from Functionalized 4-Aminoprolines
Natchus, Michael G, Bookland, Roger G, De, Biswanath, Almstead, Neil G, Pikul, Stanislaw, Janusz, Michael J, Heitmeyer, Sandra A, Hookfin, Erin B, Hsieh, Lily C, Dowty, Martin E, Dietsch, Charles R, Patel, Vikram S, Garver, Susan M, Gu, Fei, Pokross, Matthew E, Mieling, Glen E, Baker, Timothy R, Foltz, David J, Peng, Sean X, Bornes, David M, Strojnowski, Michael J, Taiwo, Yetunde O
Published in Journal of medicinal chemistry (28.12.2000)
Published in Journal of medicinal chemistry (28.12.2000)
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Journal Article
Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines
Natchus, Michael G, Bookland, Roger G, Laufersweiler, Matthew J, Pikul, Staszek, Almstead, Neil G, De, Biswanath, Janusz, Michael J, Hsieh, Lily C, Gu, Fei, Pokross, Matthew E, Patel, Vikram S, Garver, Susan M, Peng, Sean X, Branch, Todd M, King, Selane L, Baker, Timothy R, Foltz, David J, Mieling, Glen E
Published in Journal of medicinal chemistry (29.03.2001)
Published in Journal of medicinal chemistry (29.03.2001)
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Journal Article
Studies on the mechanism and origin of stereoselective opening of chiral dioxane acetals
Denmark, Scott E, Almstead, Neil G
Published in Journal of the American Chemical Society (01.10.1991)
Published in Journal of the American Chemical Society (01.10.1991)
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Journal Article
Spectroscopic studies on the structure and conformation of Lewis acid-aldehyde complexes
Denmark, Scott E, Almstead, Neil G
Published in Journal of the American Chemical Society (01.04.1993)
Published in Journal of the American Chemical Society (01.04.1993)
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Journal Article
Heterocycle-based MMP Inhibitors with P2′ Substituents
Pikul, Stanislaw, Dunham, Kelly McDow, Almstead, Neil G, De, Biswanath, Natchus, Michael G, Taiwo, Yetunde O, Williams, Lisa E, Hynd, Barbara A, Hsieh, Lily C, Janusz, Michael J, Gu, Fei, Mieling, Glen E
Published in Bioorganic & medicinal chemistry letters (23.04.2001)
Published in Bioorganic & medicinal chemistry letters (23.04.2001)
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Journal Article
The Next Generation of MMP Inhibitors: Design and Synthesis
DE, BISWANATH, NATCHUS, MICHAEL G., CHENG, MENYAN, PIKUL, STANISLAW, ALMSTEAD, NEIL G., TAIWO, YETUNDE O., SNIDER, CATHERINE E., CHEN, LONGYIN, BARNETT, BOBBY, GU, FEI, DOWTY, MARTIN
Published in Annals of the New York Academy of Sciences (01.06.1999)
Published in Annals of the New York Academy of Sciences (01.06.1999)
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Journal Article
The development of new carboxylic acid-based MMP inhibitors derived from a cyclohexylglycine scaffold
Tullis, Joshua S., Laufersweiler, Matthew J., VanRens, John C., Natchus, Michael G., Bookland, Roger G., Almstead, Neil G., Pikul, Stanislaw, De, Biswanath, Hsieh, Lily C., Janusz, Michael J., Branch, Todd M., Peng, Sean X., Jin, Yingkun Y., Hudlicky, Tomas, Oppong, Kofi
Published in Bioorganic & medicinal chemistry letters (06.08.2001)
Published in Bioorganic & medicinal chemistry letters (06.08.2001)
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Journal Article
Gas chromatographic–mass spectrometric analysis of hydroxylamine for monitoring the metabolic hydrolysis of metalloprotease inhibitors in rat and human liver microsomes
Peng, Sean X., Strojnowski, Michael J., Hu, Joanna K., Smith, Bill J., Eichhold, Thomas H., Wehmeyer, Kenneth R., Pikul, Stanislaw, Almstead, Neil G.
Published in Journal of chromatography. B, Biomedical sciences and applications (05.03.1999)
Published in Journal of chromatography. B, Biomedical sciences and applications (05.03.1999)
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