SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir
Mesci, Pinar, de Souza, Janaina S, Martin-Sancho, Laura, Macia, Angela, Saleh, Aurian, Yin, Xin, Snethlage, Cedric, Adams, Jason W, Avansini, Simoni H, Herai, Roberto H, Almenar-Queralt, Angels, Pu, Yuan, Szeto, Ryan A, Goldberg, Gabriela, Bruck, Patrick T, Papes, Fabio, Chanda, Sumit K, Muotri, Alysson R
Published in PLoS biology (03.11.2022)
Published in PLoS biology (03.11.2022)
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Journal Article
Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells
Ma, Qi, Yang, Feng, Mackintosh, Carlos, Jayani, Ranveer Singh, Oh, Soohwan, Jin, Chunyu, Nair, Sreejith Janardhanan, Merkurjev, Daria, Ma, Wubin, Allen, Stephanie, Wang, Dong, Almenar-Queralt, Angels, Garcia-Bassets, Ivan
Published in Cell reports (Cambridge) (21.04.2020)
Published in Cell reports (Cambridge) (21.04.2020)
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Journal Article
Chromatin establishes an immature version of neuronal protocadherin selection during the naive-to-primed conversion of pluripotent stem cells
Almenar-Queralt, Angels, Merkurjev, Daria, Kim, Hong Sook, Navarro, Michael, Ma, Qi, Chaves, Rodrigo S., Allegue, Catarina, Driscoll, Shawn P., Chen, Andrew G., Kohlnhofer, Bridget, Fong, Lauren K., Woodruff, Grace, Mackintosh, Carlos, Bohaciakova, Dasa, Hruska-Plochan, Marian, Tadokoro, Takahiro, Young, Jessica E., El Hajj, Nady, Dittrich, Marcus, Marsala, Martin, Goldstein, Lawrence S. B., Garcia-Bassets, Ivan
Published in Nature genetics (01.12.2019)
Published in Nature genetics (01.12.2019)
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Journal Article
Proteasome stress leads to APP axonal transport defects by promoting its amyloidogenic processing in lysosomes
Otero, María Gabriela, Fernandez Bessone, Ivan, Hallberg, Alan Earle, Cromberg, Lucas Eneas, De Rossi, María Cecilia, Saez, Trinidad M, Levi, Valeria, Almenar-Queralt, Angels, Falzone, Tomás Luis
Published in Journal of cell science (01.06.2018)
Published in Journal of cell science (01.06.2018)
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Journal Article
Caveolin-1 regulation of disrupted-in-schizophrenia-1 as a potential therapeutic target for schizophrenia
Kassan, Adam, Egawa, Junji, Zhang, Zheng, Almenar-Queralt, Angels, Nguyen, Quynh My, Lajevardi, Yasaman, Kim, Kaitlyn, Posadas, Edmund, Jeste, Dilip V, Roth, David M, Patel, Piyush M, Patel, Hemal H, Head, Brian P
Published in Journal of neurophysiology (01.01.2017)
Published in Journal of neurophysiology (01.01.2017)
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Journal Article
Caveolin-1 Phosphorylation Is Essential for Axonal Growth of Human Neurons Derived From iPSCs
Wang, Shanshan, Zhang, Zheng, Almenar-Queralt, Angels, Leem, Joseph, DerMardirossian, Celine, Roth, David M, Patel, Piyush M, Patel, Hemal H, Head, Brian P
Published in Frontiers in cellular neuroscience (17.07.2019)
Published in Frontiers in cellular neuroscience (17.07.2019)
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Journal Article
UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport
Almenar-Queralt, Angels, Falzone, Tomas L, Shen, Zhouxin, Lillo, Concepcion, Killian, Rhiannon L, Arreola, Angela S, Niederst, Emily D, Ng, Kheng S, Kim, Sonia N, Briggs, Steven P, Williams, David S, Goldstein, Lawrence S B
Published in The Journal of neuroscience (26.02.2014)
Published in The Journal of neuroscience (26.02.2014)
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Journal Article
Sunday Driver Interacts with Two Distinct Classes of Axonal Organelles
Abe, Namiko, Almenar-Queralt, Angels, Lillo, Concepcion, Shen, Zhouxin, Lozach, Jean, Briggs, Steven P., Williams, David S., Goldstein, Lawrence S.B., Cavalli, Valeria
Published in The Journal of biological chemistry (11.12.2009)
Published in The Journal of biological chemistry (11.12.2009)
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Journal Article
Actin dynamics at pointed ends regulates thin filament length in striated muscle
Fowler, Velia M, Littlefield, Ryan, Almenar-Queralt, Angels
Published in Nature cell biology (01.06.2001)
Published in Nature cell biology (01.06.2001)
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Journal Article
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism
Killian, Rhiannon L, Flippin, Jessica D, Herrera, Cheryl M, Almenar-Queralt, Angels, Goldstein, Lawrence S B
Published in PloS one (17.01.2012)
Published in PloS one (17.01.2012)
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Journal Article
Identification of a Novel Tropomodulin Isoform, Skeletal Tropomodulin, That Caps Actin Filament Pointed Ends in Fast Skeletal Muscle
Almenar-Queralt, Angels, Lee, Andria, Conley, Catharine A., de Pouplana, Lluís Ribas, Fowler, Velia M.
Published in The Journal of biological chemistry (01.10.1999)
Published in The Journal of biological chemistry (01.10.1999)
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Journal Article
Pathophysiology Associated with Traumatic Brain Injury: Current Treatments and Potential Novel Therapeutics
Pearn, Matthew L., Niesman, Ingrid R., Egawa, Junji, Sawada, Atsushi, Almenar-Queralt, Angels, Shah, Sameer B., Duckworth, Josh L., Head, Brian P.
Published in Cellular and molecular neurobiology (01.05.2017)
Published in Cellular and molecular neurobiology (01.05.2017)
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Journal Article
Amyloidogenic Processing of Amyloid Precursor Protein Drives Stretch-Induced Disruption of Axonal Transport in hiPSC-Derived Neurons
Chaves, Rodrigo S, Tran, My, Holder, Andrew R, Balcer, Alexandra M, Dickey, Andrea M, Roberts, Elizabeth A, Bober, Brian G, Gutierrez, Edgar, Head, Brian P, Groisman, Alex, Goldstein, Lawrence S B, Almenar-Queralt, Angels, Shah, Sameer B
Published in The Journal of neuroscience (08.12.2021)
Published in The Journal of neuroscience (08.12.2021)
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Journal Article
SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir
Pinar Mesci, Janaina S. de Souza, Laura Martin-Sancho, Angela Macia, Aurian Saleh, Xin Yin, Cedric Snethlage, Jason W. Adams, Simoni H. Avansini, Roberto H. Herai, Angels Almenar-Queralt, Yuan Pu, Ryan A. Szeto, Gabriela Goldberg, Patrick T. Bruck, Fabio Papes, Sumit K. Chanda, Alysson R. Muotri
Published in PLoS biology (01.11.2022)
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Published in PLoS biology (01.11.2022)
Journal Article
Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function
Otero, Maria G, Alloatti, Matías, Cromberg, Lucas E, Almenar-Queralt, Angels, Encalada, Sandra E, Pozo Devoto, Victorio M, Bruno, Luciana, Goldstein, Lawrence S B, Falzone, Tomás L
Published in Journal of cell science (01.04.2014)
Published in Journal of cell science (01.04.2014)
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Journal Article
Presenilins Regulate Neurotrypsin Gene Expression and Neurotrypsin-dependent Agrin Cleavage via Cyclic AMP Response Element-binding Protein (CREB) Modulation
Almenar-Queralt, Angels, Kim, Sonia N., Benner, Christopher, Herrera, Cheryl M., Kang, David E., Garcia-Bassets, Ivan, Goldstein, Lawrence S.B.
Published in The Journal of biological chemistry (06.12.2013)
Published in The Journal of biological chemistry (06.12.2013)
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Journal Article
Amyloid precursor protein-induced axonopathies are independent of amyloid-β peptides
Stokin, Gorazd B., Almenar-Queralt, Angels, Gunawardena, Shermali, Rodrigues, Elizabeth M., Falzone, Tomás, Kim, Jungsu, Lillo, Concepción, Mount, Stephanie L., Roberts, Elizabeth A., McGowan, Eileen, Williams, David S., Goldstein, Lawrence S.B.
Published in Human molecular genetics (15.11.2008)
Published in Human molecular genetics (15.11.2008)
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Journal Article
Amyloid precursor protein-induced axonopathies are independent of amyloid-[beta] peptides
Stokin, Gorazd B, Almenar-queralt, Angels, Gunawardena, Shermali, Rodrigues, Elizabeth M, Falzone, Tomás, Kim, Jungsu, Lillo, Concepción, Mount, Stephanie L, Roberts, Elizabeth A, Mcgowan, Eileen, Williams, David S, Lawrence S.b. Goldstein
Published in Human molecular genetics (15.11.2008)
Published in Human molecular genetics (15.11.2008)
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Journal Article