Identification of Galanin and Its Receptor GalR1 as Novel Determinants of Resistance to Chemotherapy and Potential Biomarkers in Colorectal Cancer
STEVENSON, Leanne, ALLEN, Wendy L, TURKINGTON, Richard, JITHESH, Puthen V, PROUTSKI, Irina, STEWART, Gail, LENZ, Heinz-Josef, VAN SCHAEYBROECK, Sandra, LONGLEY, Daniel B, JOHNSTON, Patrick G
Published in Clinical cancer research (01.10.2012)
Published in Clinical cancer research (01.10.2012)
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Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway
Stevenson, Leanne, Allen, Wendy L, Proutski, Irina, Stewart, Gail, Johnston, Louise, McCloskey, Karen, Wilson, Peter M, Longley, Daniel B, Johnston, Patrick G
Published in PloS one (24.05.2011)
Published in PloS one (24.05.2011)
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Pharmacogenomic identification of novel determinants of response to chemotherapy in colon cancer
BOYER, John, ALLEN, Wendy L, MCLEAN, Estelle G, WILSON, Peter M, MCCULLA, Andrea, MOORE, Stephen, LONGLEY, Daniel B, CALDAS, Carlos, JOHNSTON, Patrick G
Published in Cancer research (Chicago, Ill.) (01.03.2006)
Published in Cancer research (Chicago, Ill.) (01.03.2006)
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Cellular FLICE-inhibitory protein regulates chemotherapy-induced apoptosis in breast cancer cells
Rogers, Katherine M A, Thomas, Michelle, Galligan, Leeona, Wilson, Timothy R, Allen, Wendy L, Sakai, Hidekazu, Johnston, Patrick G, Longley, Daniel B
Published in Molecular cancer therapeutics (01.05.2007)
Published in Molecular cancer therapeutics (01.05.2007)
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Prostate-derived factor—a novel inhibitor of drug-induced cell death in colon cancer cells
Proutski, Irina, Stevenson, Leanne, Allen, Wendy L, McCulla, Andrea, Boyer, John, McLean, Estelle G, Longley, Daniel B, Johnston, Patrick G
Published in Molecular cancer therapeutics (01.09.2009)
Published in Molecular cancer therapeutics (01.09.2009)
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Challenging the Cancer Molecular Stratification Dogma: Intratumoral Heterogeneity Undermines Consensus Molecular Subtypes and Potential Diagnostic Value in Colorectal Cancer
Dunne, Philip D, McArt, Darragh G, Bradley, Conor A, O'Reilly, Paul G, Barrett, Helen L, Cummins, Robert, O'Grady, Tony, Arthur, Ken, Loughrey, Maurice B, Allen, Wendy L, McDade, Simon S, Waugh, David J, Hamilton, Peter W, Longley, Daniel B, Kay, Elaine W, Johnston, Patrick G, Lawler, Mark, Salto-Tellez, Manuel, Van Schaeybroeck, Sandra
Published in Clinical cancer research (15.08.2016)
Published in Clinical cancer research (15.08.2016)
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Clinical Determinants of Response to Irinotecan-Based Therapy Derived from Cell Line Models
ALLEN, Wendy L, COYLE, Vicky M, JOHNSTON, Patrick G, JITHESH, Puthen V, PROUTSKI, Irina, STEVENSON, Leanne, FENNING, Cathy, LONGLEY, Daniel B, WILSON, Richard H, GORDON, Michael, LENZ, Heinz-Josef
Published in Clinical cancer research (15.10.2008)
Published in Clinical cancer research (15.10.2008)
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Implementing prognostic and predictive biomarkers in CRC clinical trials
Johnston, Patrick G, Van Schaeybroeck, Sandra, Allen, Wendy L, Turkington, Richard C
Published in Nature reviews. Clinical oncology (01.04.2011)
Published in Nature reviews. Clinical oncology (01.04.2011)
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The colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information
Allen, Wendy L, Jithesh, Puthen V, Oliver, Gavin R, Proutski, Irina, Longley, Daniel B, Lenz, Heinz-Josef, Proutski, Vitali, Harkin, Paul, Johnston, Patrick G
Published in BMC cancer (20.12.2010)
Published in BMC cancer (20.12.2010)
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Drug resistance, predictive markers and pharmacogenomics in colorectal cancer
Longley, Daniel B, Allen, Wendy L., Johnston, Patrick G.
Published in Biochimica et biophysica acta (01.12.2006)
Published in Biochimica et biophysica acta (01.12.2006)
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The pseudo-caspase FLIP(L) regulates cell fate following p53 activation
Lees, Andrea, McIntyre, Alexander J., Crawford, Nyree T., Falcone, Fiammetta, McCann, Christopher, Holohan, Caitriona, Quinn, Gerard P., Roberts, Jamie Z., Sessler, Tamas, Gallagher, Peter F., Gregg, Gemma M. A., McAllister, Katherine, McLaughlin, Kirsty M., Allen, Wendy L., Egan, Laurence J., Ryan, Aideen E., Labonte-Wilson, Melissa J., Dunne, Philip D., Wappett, Mark, Coyle, Vicky M., Johnston, Patrick G., Kerr, Emma M., Longley, Daniel B., McDade, Simon S.
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (28.07.2020)
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The Unfolded Protein Response: A Novel Therapeutic Target for Poor Prognostic BRAF Mutant Colorectal Cancer
Forsythe, Nicholas, Refaat, Alaa, Javadi, Arman, Khawaja, Hajrah, Weir, Jessica-Anne, Emam, Heba, Allen, Wendy L, Burkamp, Frank, Popovici, Vlad, Jithesh, Puthen V, Isella, Claudio, Labonte, Melissa J, Mills, Ian G, Johnston, Patrick G, Van Schaeybroeck, Sandra
Published in Molecular cancer therapeutics (01.06.2018)
Published in Molecular cancer therapeutics (01.06.2018)
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RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer
Khawaja, Hajrah, Campbell, Andrew, Roberts, Jamie Z, Javadi, Arman, O'Reilly, Paul, McArt, Darragh, Allen, Wendy L, Majkut, Joanna, Rehm, Markus, Bardelli, Alberto, Di Nicolantonio, Federica, Scott, Christopher J, Kennedy, Richard, Vitale, Nicolas, Harrison, Timothy, Sansom, Owen J, Longley, Daniel B, Evergren, Emma, Van Schaeybroeck, Sandra
Published in Cell death & disease (29.10.2020)
Published in Cell death & disease (29.10.2020)
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Immune-Derived PD-L1 Gene Expression Defines a Subgroup of Stage II/III Colorectal Cancer Patients with Favorable Prognosis Who May Be Harmed by Adjuvant Chemotherapy
Dunne, Philip D, McArt, Darragh G, O'Reilly, Paul G, Coleman, Helen G, Allen, Wendy L, Loughrey, Maurice, Van Schaeybroeck, Sandra, McDade, Simon, Salto-Tellez, Manuel, Longley, Daniel B, Lawler, Mark, Johnston, Patrick G
Published in Cancer immunology research (01.07.2016)
Published in Cancer immunology research (01.07.2016)
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A systems biology approach identifies SART1 as a novel determinant of both 5-fluorouracil and SN38 drug resistance in colorectal cancer
Allen, Wendy L, Stevenson, Leanne, Coyle, Vicky M, Jithesh, Puthen V, Proutski, Irina, Carson, Gail, Gordon, Michael A, Lenz, Heinz-Josef D, Van Schaeybroeck, Sandra, Longley, Daniel B, Johnston, Patrick G
Published in Molecular cancer therapeutics (01.01.2012)
Published in Molecular cancer therapeutics (01.01.2012)
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Pharmacogenomic profiling and pathway analyses identify MAPK-dependent migration as an acute response to SN38 in p53 null and p53-mutant colorectal cancer cells
Allen, Wendy L, Turkington, Richard C, Stevenson, Leanne, Carson, Gail, Coyle, Vicky M, Hector, Suzanne, Dunne, Philip, Van Schaeybroeck, Sandra, Longley, Daniel B, Johnston, Patrick G
Published in Molecular cancer therapeutics (01.08.2012)
Published in Molecular cancer therapeutics (01.08.2012)
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The role of thymidylate synthase induction in modulating p53-regulated gene expression in response to 5-fluorouracil and antifolates
LONGLEY, Daniel B, BOYER, John, ALLEN, Wendy L, LATIF, Tariq, FERGUSON, Paul R, MAXWELL, Pamela J, MCDERMOTT, Ultan, LYNCH, Maria, HARKIN, D. Paul, JOHNSTON, Patrick G
Published in Cancer research (Chicago, Ill.) (01.05.2002)
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Published in Cancer research (Chicago, Ill.) (01.05.2002)
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Predicting the outcome of chemotherapy for colorectal cancer
Allen, Wendy L, Coyle, Vicky M, Johnston, Patrick G
Published in Current opinion in pharmacology (01.08.2006)
Published in Current opinion in pharmacology (01.08.2006)
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