PARP1 Trapping by PARP Inhibitors Drives Cytotoxicity in Both Cancer Cells and Healthy Bone Marrow
Hopkins, Todd A, Ainsworth, William B, Ellis, Paul A, Donawho, Cherrie K, DiGiammarino, Enrico L, Panchal, Sanjay C, Abraham, Vivek C, Algire, Mikkel A, Shi, Yan, Olson, Amanda M, Johnson, Eric F, Wilsbacher, Julie L, Maag, David
Published in Molecular cancer research (01.02.2019)
Published in Molecular cancer research (01.02.2019)
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The Eukaryotic Translation Initiation Factors eIF1 and eIF1A Induce an Open Conformation of the 40S Ribosome
Passmore, Lori A., Schmeing, T. Martin, Maag, David, Applefield, Drew J., Acker, Michael G., Algire, Mikkel A., Lorsch, Jon R., Ramakrishnan, V.
Published in Molecular cell (13.04.2007)
Published in Molecular cell (13.04.2007)
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One-step assembly in yeast of 25 overlapping DNA fragments to form a complete synthetic Mycoplasma genitalium genome
Gibson, Daniel G, Benders, Gwynedd A, Axelrod, Kevin C, Zaveri, Jayshree, Algire, Mikkel A, Moodie, Monzia, Montague, Michael G, Venter, J. Craig, Smith, Hamilton O, Hutchison, Clyde A. III
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (23.12.2008)
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Synthetic generation of influenza vaccine viruses for rapid response to pandemics
Dormitzer, Philip R, Suphaphiphat, Pirada, Gibson, Daniel G, Wentworth, David E, Stockwell, Timothy B, Algire, Mikkel A, Alperovich, Nina, Barro, Mario, Brown, David M, Craig, Stewart, Dattilo, Brian M, Denisova, Evgeniya A, De Souza, Ivna, Eickmann, Markus, Dugan, Vivien G, Ferrari, Annette, Gomila, Raul C, Han, Liqun, Judge, Casey, Mane, Sarthak, Matrosovich, Mikhail, Merryman, Chuck, Palladino, Giuseppe, Palmer, Gene A, Spencer, Terika, Strecker, Thomas, Trusheim, Heidi, Uhlendorff, Jennifer, Wen, Yingxia, Yee, Anthony C, Zaveri, Jayshree, Zhou, Bin, Becker, Stephan, Donabedian, Armen, Mason, Peter W, Glass, John I, Rappuoli, Rino, Venter, J Craig
Published in Science translational medicine (15.05.2013)
Published in Science translational medicine (15.05.2013)
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SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding
Curtin, Michael L., Pliushchev, Marina A., Li, Huan-Qiu, Torrent, Maricel, Dietrich, Justin D., Jakob, Clarissa G., Zhu, Haizhong, Zhao, Hongyu, Wang, Ying, Ji, Zhiqin, Clark, Richard F., Sarris, Kathy A., Selvaraju, Sujatha, Shaw, Bailin, Algire, Mikkel A., He, Yupeng, Richardson, Paul L., Sweis, Ramzi F., Sun, Chaohong, Chiang, Gary G., Michaelides, Michael R.
Published in Bioorganic & medicinal chemistry letters (01.04.2017)
Published in Bioorganic & medicinal chemistry letters (01.04.2017)
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Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo
Cheung, Yuen-Nei, Maag, David, Mitchell, Sarah F, Fekete, Christie A, Algire, Mikkel A, Takacs, Julie E, Shirokikh, Nikolay, Pestova, Tatyana, Lorsch, Jon R, Hinnebusch, Alan G
Published in Genes & development (15.05.2007)
Published in Genes & development (15.05.2007)
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A Type III restriction–modification system in Mycoplasma mycoides subsp. capri
Algire, Mikkel A., Montague, Michael G., Vashee, Sanjay, Lartigue, Carole, Merryman, Chuck
Published in Open biology (01.10.2012)
Published in Open biology (01.10.2012)
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Development and characterization of a reconstituted yeast translation initiation system
ALGIRE, MIKKEL A., MAAG, DAVID, SAVIO, PETER, ACKER, MICHAEL G., TARUN, SALVADOR Z., SACHS, ALAN B., ASANO, KATSURA, NIELSEN, KLAUS H., OLSEN, DEANNE S., PHAN, LON, HINNEBUSCH, ALAN G., LORSCH, JON R.
Published in RNA (Cambridge) (01.03.2002)
Published in RNA (Cambridge) (01.03.2002)
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N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection
Fekete, Christie A, Mitchell, Sarah F, Cherkasova, Vera A, Applefield, Drew, Algire, Mikkel A, Maag, David, Saini, Adesh K, Lorsch, Jon R, Hinnebusch, Alan G
Published in The EMBO journal (21.03.2007)
Published in The EMBO journal (21.03.2007)
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Complete Chemical Synthesis, Assembly, and Cloning of a Mycoplasma genitalium Genome
Gibson, Daniel G, Benders, Gwynedd A, Andrews-Pfannkoch, Cynthia, Denisova, Evgeniya A, Baden-Tillson, Holly, Zaveri, Jayshree, Stockwell, Timothy B, Brownley, Anushka, Thomas, David W, Algire, Mikkel A, Merryman, Chuck, Young, Lei, Noskov, Vladimir N, Glass, John I, Venter, J. Craig, Hutchison, Clyde A. III, Smith, Hamilton O
Published in Science (American Association for the Advancement of Science) (29.02.2008)
Published in Science (American Association for the Advancement of Science) (29.02.2008)
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The 5′-7-Methylguanosine Cap on Eukaryotic mRNAs Serves Both to Stimulate Canonical Translation Initiation and to Block an Alternative Pathway
Mitchell, Sarah F., Walker, Sarah E., Algire, Mikkel A., Park, Eun-Hee, Hinnebusch, Alan G., Lorsch, Jon R.
Published in Molecular cell (24.09.2010)
Published in Molecular cell (24.09.2010)
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Creating Bacterial Strains from Genomes That Have Been Cloned and Engineered in Yeast
Lartigue, Carole, Vashee, Sanjay, Algire, Mikkel A, Chuang, Ray-Yuan, Benders, Gwynedd A, Ma, Li, Noskov, Vladimir N, Denisova, Evgeniya A, Gibson, Daniel G, Assad-Garcia, Nacyra, Alperovich, Nina, Thomas, David W, Merryman, Chuck, Hutchison, Clyde A. III, Smith, Hamilton O, Venter, J. Craig, Glass, John I
Published in Science (American Association for the Advancement of Science) (25.09.2009)
Published in Science (American Association for the Advancement of Science) (25.09.2009)
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Cloning whole bacterial genomes in yeast
Benders, Gwynedd A, Noskov, Vladimir N, Denisova, Evgeniya A, Lartigue, Carole, Gibson, Daniel G, Assad-Garcia, Nacyra, Chuang, Ray-Yuan, Carrera, William, Moodie, Monzia, Algire, Mikkel A, Phan, Quang, Alperovich, Nina, Vashee, Sanjay, Merryman, Chuck, Venter, J. Craig, Smith, Hamilton O, Glass, John I, Hutchison, Clyde A. III
Published in Nucleic Acids Research (01.05.2010)
Published in Nucleic Acids Research (01.05.2010)
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SAR and characterization of non-substrate isoindoline urea inhibitors of nicotinamide phosphoribosyltransferase (NAMPT)
Curtin, Michael L., Heyman, H. Robin, Clark, Richard F., Sorensen, Bryan K., Doherty, George A., Hansen, T. Matthew, Frey, Robin R., Sarris, Kathy A., Aguirre, Ana L., Shrestha, Anurupa, Tu, Noah, Woller, Kevin, Pliushchev, Marina A., Sweis, Ramzi F., Cheng, Min, Wilsbacher, Julie L., Kovar, Peter J., Guo, Jun, Cheng, Dong, Longenecker, Kenton L., Raich, Diana, Korepanova, Alla V., Soni, Nirupama B., Algire, Mikkel A., Richardson, Paul L., Marin, Violeta L., Badagnani, Ilaria, Vasudevan, Anil, Buchanan, F. Greg, Maag, David, Chiang, Gary G., Tse, Chris, Michaelides, Michael R.
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
Published in Bioorganic & medicinal chemistry letters (01.08.2017)
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Journal Article
N‐ and C‐terminal residues of eIF1A have opposing effects on the fidelity of start codon selection
Fekete, Christie A, Mitchell, Sarah F, Cherkasova, Vera A, Applefield, Drew, Algire, Mikkel A, Maag, David, Saini, Adesh K, Lorsch, Jon R, Hinnebusch, Alan G
Published in The EMBO journal (21.03.2007)
Published in The EMBO journal (21.03.2007)
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