Development of a Genetic System for Combinatorial Biosynthesis of Lipopeptides in Streptomyces fradiae and Heterologous Expression of the A54145 Biosynthesis Gene Cluster
Alexander, Dylan C, Rock, Jessica, He, Xiaowei, Brian, Paul, Miao, Vivian, Baltz, Richard H
Published in Applied and Environmental Microbiology (01.10.2010)
Published in Applied and Environmental Microbiology (01.10.2010)
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Journal Article
Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties
NGUYEN, Kien T, XIAOWEI HE, BRIAN, Paul, BALTZ, Richard H, ALEXANDER, Dylan C, CHEN LI, GU, Jian-Qiao, MASCIO, Carmela, VAN PRAAGH, Andrew, MORTIN, Larry, MIN CHU, SILVERMAN, Jared A
Published in Antimicrobial Agents and Chemotherapy (01.04.2010)
Published in Antimicrobial Agents and Chemotherapy (01.04.2010)
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Pharmacokinetics-Pharmacodynamics of CB-618 in Combination with Cefepime, Ceftazidime, Ceftolozane, or Meropenem: the Pharmacological Basis for a Stand-Alone β-Lactamase Inhibitor
Ambrose, Paul G, VanScoy, Brian D, Trang, Michael, McCauley-Miller, Jennifer, Conde, Haley, Bhavnani, Sujata M, Alexander, Dylan C, Friedrich, Lawrence V
Published in Antimicrobial agents and chemotherapy (01.12.2017)
Published in Antimicrobial agents and chemotherapy (01.12.2017)
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Journal Article
Pharmacokinetics-Pharmacodynamics of a Novel β-Lactamase Inhibitor, CB-618, in Combination with Meropenem in an In Vitro Infection Model
VanScoy, Brian D, Trang, Michael, McCauley, Jennifer, Conde, Haley, Bhavnani, Sujata M, Friedrich, Lawrence V, Alexander, Dylan C, Ambrose, Paul G
Published in Antimicrobial agents and chemotherapy (01.07.2016)
Published in Antimicrobial agents and chemotherapy (01.07.2016)
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Journal Article
Thermal stability and kinetic constants for 129 variants of a family 1 glycoside hydrolase reveal that enzyme activity and stability can be separately designed
Carlin, Dylan Alexander, Hapig-Ward, Siena, Chan, Bill Wayne, Damrau, Natalie, Riley, Mary, Caster, Ryan W, Bethards, Bowen, Siegel, Justin B
Published in PloS one (22.05.2017)
Published in PloS one (22.05.2017)
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Kinetic Characterization of 100 Glycoside Hydrolase Mutants Enables the Discovery of Structural Features Correlated with Kinetic Constants
Carlin, Dylan Alexander, Caster, Ryan W, Wang, Xiaokang, Betzenderfer, Stephanie A, Chen, Claire X, Duong, Veasna M, Ryklansky, Carolina V, Alpekin, Alp, Beaumont, Nathan, Kapoor, Harshul, Kim, Nicole, Mohabbot, Hosna, Pang, Boyu, Teel, Rachel, Whithaus, Lillian, Tagkopoulos, Ilias, Siegel, Justin B
Published in PloS one (27.01.2016)
Published in PloS one (27.01.2016)
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Journal Article
Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions
Alexander, Dylan C, Rock, Jessica, Gu, Jian-Qiao, Mascio, Carmela, Chu, Min, Brian, Paul, Baltz, Richard H
Published in Journal of antibiotics (01.01.2011)
Published in Journal of antibiotics (01.01.2011)
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Journal Article
Structural characterization of a lipopeptide antibiotic A54145E(Asn3Asp9) produced by a genetically engineered strain of Streptomyces fradiae
Gu, Jian-Qiao, Alexander, Dylan C, Rock, Jessica, Brian, Paul, Chu, Min, Baltz, Richard H
Published in Journal of antibiotics (2011)
Published in Journal of antibiotics (2011)
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Journal Article
pcd Mutants of Streptomyces clavuligerus Still Produce Cephamycin C
ALEXANDER, Dylan C, ANDERS, Cecilia L, LEE, Linda, JENSEN, Susan E
Published in Journal of Bacteriology (01.08.2007)
Published in Journal of Bacteriology (01.08.2007)
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Journal Article
The positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is mistranslated in a bldA mutant
Trepanier, Nicole K, Jensen, Susan E, Alexander, Dylan C, Leskiw, Brenda K
Published in Microbiology (Society for General Microbiology) (01.03.2002)
Published in Microbiology (Society for General Microbiology) (01.03.2002)
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Journal Article
Preparing for Year 12 examinations: Predictors of psychological distress and sleep
Robinson, Julie Ann, Alexander, Dylan James, Gradisar, Michael Shane
Published in Australian journal of psychology (01.06.2009)
Published in Australian journal of psychology (01.06.2009)
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Journal Article
Development of the Micromonospora carbonacea var. africana ATCC 39149 bacteriophage pMLP1 integrase for site-specific integration in Micromonospora spp
Alexander, Dylan C, Devlin, David J, Hewitt, Duane D, Horan, Ann C, Hosted, Thomas J
Published in Microbiology (Society for General Microbiology) (01.09.2003)
Published in Microbiology (Society for General Microbiology) (01.09.2003)
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Journal Article
The live biotherapeutic SYNB1353 decreases plasma methionine via directed degradation in animal models and healthy volunteers
Perreault, Mylène, Means, Jillian, Gerson, Erik, James, Michael, Cotton, Sean, Bergeron, Christopher G., Simon, Mark, Carlin, Dylan Alexander, Schmidt, Nathan, Moore, Theodore C., Blasbalg, Julie, Sondheimer, Neal, Ndugga-Kabuye, Kenneth, Denney, William S., Isabella, Vincent M., Lubkowicz, David, Brennan, Aoife, Hava, David L.
Published in Cell host & microbe (13.03.2024)
Published in Cell host & microbe (13.03.2024)
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