Platinum(IV) Complex with Adamantylamine as Nonleaving Amine Group: Synthesis, Characterization, and in Vitro Antitumor Activity against a Panel of Cisplatin-Resistant Cancer Cell Lines
Žák, František, Turánek, Jaroslav, Kroutil, Aleš, Sova, Petr, Mistr, Adolf, Poulová, Anna, Mikolin, Petr, Žák, Zdirad, Kašná, Andrea, Záluská, Dana, Neča, Jiří, Šindlerová, Lenka, Kozubík, Alois
Published in Journal of medicinal chemistry (29.01.2004)
Published in Journal of medicinal chemistry (29.01.2004)
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Arylaminopropanone Derivatives as Potential Cholinesterase Inhibitors: Synthesis, Docking Study and Biological Evaluation
Hudcová, Anna, Kroutil, Aleš, Kubínová, Renata, Garro, Adriana D, Gutierrez, Lucas J, Enriz, Daniel, Oravec, Michal, Csöllei, Jozef
Published in Molecules (Basel, Switzerland) (10.04.2020)
Published in Molecules (Basel, Switzerland) (10.04.2020)
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High effectiveness of platinum(IV) complex with adamantylamine in overcoming resistance to cisplatin and suppressing proliferation of ovarian cancer cells in vitro
Kozubík, Alois, Horváth, Viktor, Švihálková-Šindlerová, Lenka, Souček, Karel, Hofmanová, Jiřina, Sova, Petr, Kroutil, Aleš, Žák, František, Mistr, Adolf, Turánek, Jaroslav
Published in Biochemical pharmacology (01.02.2005)
Published in Biochemical pharmacology (01.02.2005)
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Platinum(IV) complex with adamantylamine overcomes intrinsic resistance to cisplatin in ovarian cancer cells
Horváth, Viktor, Blanářová, Olga, Švihálková-Šindlerová, Lenka, Souček, Karel, Hofmanová, Jiřina, Sova, Petr, Kroutil, Aleš, Fedoročko, Peter, Kozubík, Alois
Published in Gynecologic oncology (01.07.2006)
Published in Gynecologic oncology (01.07.2006)
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Synthesis and transdermal penetration-enhancing activity of carbonic and carbamic acid esters—Comparison with transkarbam 12
Klimentová, Jana, Hrabálek, Alexandr, Vávrová, Kateřina, Holas, Tomáš, Kroutil, Aleš
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
Published in Bioorganic & medicinal chemistry letters (01.04.2006)
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New platinum(IV) complex with adamantylamine ligand as a promising anti-cancer drug: comparison of in vitro cytotoxic potential towards A2780/cisR cisplatin-resistant cell line within homologous series of platinum(IV) complexes
Turánek, Jaroslav, Kasná, Andrea, Záluská, Dana, Neca, Jirí, Kvardová, Veronika, Knötigová, Pavlína, Horváth, Viktor, SIndlerová, Lenka, Kozubík, Alois, Sova, Petr, Kroutil, Ales, Zák, Frantisek, Mistr, Adolf
Published in Anti-cancer drugs (01.06.2004)
Published in Anti-cancer drugs (01.06.2004)
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A comparative study of pharmacokinetics, urinary excretion and tissue distribution of platinum in rats following a single-dose oral administration of two platinum(IV) complexes LA-12 (OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum(IV) and satraplatin (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum(IV)
Sova, Petr, Mistr, Adolf, Kroutil, Ales, Semerád, Martin, Chlubnová, Hana, Hrusková, Veronika, Chládková, Jirina, Chládek, Jaroslav
Published in Cancer chemotherapy and pharmacology (01.06.2011)
Published in Cancer chemotherapy and pharmacology (01.06.2011)
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A comparative study of pharmacokinetics, urinary excretion and tissue distribution of platinum in rats following a single-dose oral administration of two platinum(IV) complexes LA-12 (OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloro platinum(IV) and satraplatin (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum(IV)
SOVA, Petr, MISTR, Adolf, KROUTIL, Ales, SEMERAD, Martin, CHLUBNOVA, Hana, HRUSKOVA, Veronika, CHLADKOVA, Jirina, CHLADEK, Jaroslav
Published in Cancer chemotherapy and pharmacology (2011)
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Published in Cancer chemotherapy and pharmacology (2011)
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Pharmacokinetics and tissue distribution of platinum in rats following single and multiple oral doses of LA-12 [( OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum(IV)]
Sova, Petr, Chladek, Jaroslav, Zak, Frantisek, Mistr, Adolf, Kroutil, Ales, Semerad, Martin, Slovak, Zdenek
Published in International journal of pharmaceutics (06.01.2005)
Published in International journal of pharmaceutics (06.01.2005)
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Preclinical anti-tumor activity of a new oral platinum(IV) drug LA-12
Sova, Petr, Mistr, Adolf, Kroutil, Ales, Zak, Frantisek, Pouckova, Pavla, Zadinova, Marie
Published in Anti-cancer drugs (01.07.2005)
Published in Anti-cancer drugs (01.07.2005)
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