CRISPR-Cas9 Targeting of Hepatitis B Virus Covalently Closed Circular DNA Generates Transcriptionally Active Episomal Variants
Martinez, Maria Guadalupe, Combe, Emmanuel, Inchauspe, Aurore, Mangeot, Philippe Emmanuel, Delberghe, Elodie, Chapus, Fleur, Neveu, Gregory, Alam, Antoine, Carter, Kara, Testoni, Barbara, Zoulim, Fabien
Published in mBio (26.04.2022)
Published in mBio (26.04.2022)
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Specific Inhibition of the VEGFR-3 Tyrosine Kinase by SAR131675 Reduces Peripheral and Tumor Associated Immunosuppressive Myeloid Cells
Espagnolle, Nicolas, Barron, Pauline, Mandron, Marie, Blanc, Isabelle, Bonnin, Jacques, Agnel, Magali, Kerbelec, Erwan, Herault, Jean Pascal, Savi, Pierre, Bono, Françoise, Alam, Antoine
Published in Cancers (28.02.2014)
Published in Cancers (28.02.2014)
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Caspase-3 Is a Component of Fas Death-Inducing Signaling Complex in Lipid Rafts and Its Activity Is Required for Complete Caspase-8 Activation during Fas-Mediated Cell Death
Aouad, Salah M, Cohen, Luchino Y, Sharif-Askari, Ehsan, Haddad, Elias K, Alam, Antoine, Sekaly, Rafick-Pierre
Published in The Journal of immunology (1950) (15.02.2004)
Published in The Journal of immunology (1950) (15.02.2004)
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Incoming Human Cytomegalovirus pp65 (UL83) Contained in Apoptotic Infected Fibroblasts Is Cross-Presented to CD8+ T Cells by Dendritic Cells
Arrode, G, Boccaccio, C, Lulé, J, Allart, S, Moinard, N, Abastado, J P, Alam, A, Davrinche, C
Published in Journal of Virology (01.11.2000)
Published in Journal of Virology (01.11.2000)
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Full-length 5'RACE identifies all major HBV transcripts in HBV-infected hepatocytes and patient serum
Stadelmayer, Bernd, Diederichs, Audrey, Chapus, Fleur, Rivoire, Michel, Neveu, Gregory, Alam, Antoine, Fraisse, Laurent, Carter, Kara, Testoni, Barbara, Zoulim, Fabien
Published in Journal of hepatology (01.07.2020)
Published in Journal of hepatology (01.07.2020)
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Expression of the human antimicrobial peptide β-defensin-1 is repressed by the EGFR-ERK-MYC axis in colonic epithelial cells
Bonamy, Clément, Sechet, Emmanuel, Amiot, Aurélien, Alam, Antoine, Mourez, Michael, Fraisse, Laurent, Sansonetti, Philippe J, Sperandio, Brice
Published in Scientific reports (21.12.2018)
Published in Scientific reports (21.12.2018)
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Journal Article
Targeting hepatitis B virus with CRISPR/Cas9 approach
Martinez, Maria Guadalupe, Inchauspe, Aurore, Delberghe, Elodie, Chapus, Fleur, Neveu, Gregory, Alam, Antoine, Carter, Kara, Testoni, Barbara, Zoulim, Fabien
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
SAT376 - Targeting hepatitis B virus with CRISPR/Cas9 approach
Martinez, Maria Guadalupe, Inchauspe, Aurore, Delberghe, Elodie, Chapus, Fleur, Neveu, Gregory, Alam, Antoine, Carter, Kara, Testoni, Barbara, Zoulim, Fabien
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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SAT-198-Full-length 5’RACE analysis discriminates all major intracellular and extracellular viral RNAs during the course of infection
Stadelmayer, Bernd, Audrey, Diederichs, Gregory, Neveu, Antoine, Alam, Laurent, Fraisse, Kara, Carter, Barbara, Testoni, Fabien, Zoulim
Published in Journal of hepatology (01.04.2019)
Published in Journal of hepatology (01.04.2019)
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Costimulation of CD40 and type-I interferon immune pathways by a bifunctional molecule in HBV infection models and healthy non-human primates
Marniquet, Xavier, Dajon, Marion, Montegut, Julie, Giusepponi, Maria Elena, Pecoraro, Michela, Vicentini, Elena, Morandini, Francesca, Zanderigo, Floriana, Federico, Denise, Bonnin, Odile, Neveu, Gregory, Blanc, Charlotte, Marcou, Christelle, Lavaux, Juliette, Didier, Michel, Boldina, Galina, Dumas, Jacques, Bouqin, Thomas, Milla, Annabelle, Watson, Hugh, Carter, Kara, Alam, Antoine
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Journal Article
Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration
Favier, Benoit, Alam, Antoine, Barron, Pauline, Bonnin, Jacques, Laboudie, Patricia, Fons, Pierre, Mandron, Marie, Herault, Jean-Pascal, Neufeld, Gera, Savi, Pierre, Herbert, Jean-Marc, Bono, Françoise
Published in Blood (15.08.2006)
Published in Blood (15.08.2006)
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A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury
Delbary-Gossart, Sandrine, Lee, Sangmi, Baroni, Marco, Lamarche, Isabelle, Arnone, Michele, Canolle, Benoit, Lin, Amity, Sacramento, Jeffrey, Salegio, Ernesto A, Castel, Marie-Noelle, Delesque-Touchard, Nathalie, Alam, Antoine, Laboudie, Patricia, Ferzaz, Badia, Savi, Pierre, Herbert, Jean-Marc, Manley, Geoffrey T, Ferguson, Adam R, Bresnahan, Jacqueline C, Bono, Françoise, Beattie, Michael S
Published in Brain (London, England : 1878) (01.06.2016)
Published in Brain (London, England : 1878) (01.06.2016)
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Abstract 4079: EVT801: a selective VEGFR3 inhibitor with the potential for combination with immune-checkpoint therapies, preclinical evidences and plans for first-in-human evaluation
Fons, Pierre, Esquerre, Michael, Paillasse, Michael, Visentin, Virgile, Dol, Frederique, Meneyrol, Jerome, Badet, Gaelle, Cogo, Eric, Vidaud, Lionel, Alam, Antoine, Blanc, Isabelle, Bono, Francoise, Lisztwan, Joanna, Poublanc, Muriel, Filleron, Thomas, Hunneyball, Ian, Delord, Jean-Pierre, Whittaker, Mark
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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AI-based antibody discovery platform identifies novel, diverse, and pharmacologically active therapeutic antibodies against multiple SARS-CoV-2 strains
Loomis, Cristina Moldovan, Lahlali, Thomas, Van Citters, Danielle, Sprague, Megan, Neveu, Gregory, Somody, Laurence, Siska, Christine C, Deming, Derrick, Asakawa, Andrew J, Amimeur, Tileli, Shaver, Jeremy M, Carbonelle, Caroline, Ketchem, Randal R, Alam, Antoine, Clark, Rutilio H
Published in Antibody therapeutics (26.09.2024)
Published in Antibody therapeutics (26.09.2024)
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Abstract 2634: EVT801: Standalone cancer immunotherapy in VEGFR3+ tumors and combination with immune checkpoint therapies in VEGFR3- tumors
Esquerré, Michael, Fons, Pierre, Badet, Gaëlle, Barron, Pauline, Kagan, Jérémy, Alam, Antoine, Meneyrol, Jérôme, Blanc, Isabelle, Broussy, Roselyne, Gaujarengues, Florence, Lisztwan, Joanna, Paillasse, Michael, Whittaker, Mark, Bono, Françoise
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Abstract 2753: Translation to the clinic of EVT801: A novel immune-oncology agent for addressing innate-driven immunosuppression into the tumor microenvironment and expanding patient population responding to immune checkpoint therapies
Fons, Pierre, Esquerre, Michael, Mazieres, Julien, Rochaix, Philippe, Gomez-Brouchet, Anne, Alam, Antoine, Bertrand, Florie, Poussereau-Pomie, Celine, Meneyrol, Jerome, Pradines, Anne, selves, janick, Rouquette, Isabelle, Blanc, Isabelle, Bono, Francoise, O'Brien, Donogh P., Paillasse, Michael, Lisztwan, Joanna, Whittaker, Mark
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities
Alam, Antoine, Blanc, Isabelle, Gueguen-Dorbes, Geneviève, Duclos, Olivier, Bonnin, Jacques, Barron, Pauline, Laplace, Marie-Claude, Morin, Gaelle, Gaujarengues, Florence, Dol, Frédérique, Hérault, Jean-Pascal, Schaeffer, Paul, Savi, Pierre, Bono, Françoise
Published in Molecular cancer therapeutics (01.08.2012)
Published in Molecular cancer therapeutics (01.08.2012)
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Cutting Edge: Soluble HLA-G1 Triggers CD95/CD95 Ligand-Mediated Apoptosis in Activated CD8+ Cells by Interacting with CD8
Fournel, Sylvie, Aguerre-Girr, Maryse, Huc, Xavier, Lenfant, Francoise, Alam, Antoine, Toubert, Antoine, Bensussan, Armand, Le Bouteiller, Philippe
Published in The Journal of immunology (1950) (15.06.2000)
Published in The Journal of immunology (1950) (15.06.2000)
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