Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle
Niewoehner, Jens, Bohrmann, Bernd, Collin, Ludovic, Urich, Eduard, Sade, Hadassah, Maier, Peter, Rueger, Petra, Stracke, Jan Olaf, Lau, Wilma, Tissot, Alain C, Loetscher, Hansruedi, Ghosh, Anirvan, Freskgård, Per-Ola
Published in Neuron (Cambridge, Mass.) (08.01.2014)
Published in Neuron (Cambridge, Mass.) (08.01.2014)
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Journal Article
Combined Inhibition of Tumor Necrosis Factor α and Interleukin‐17 As a Therapeutic Opportunity in Rheumatoid Arthritis: Development and Characterization of a Novel Bispecific Antibody
Fischer, Jens A. A., Hueber, Axel J., Wilson, Stacy, Galm, Margarete, Baum, Wolfgang, Kitson, Christopher, Auer, Johannes, Lorenz, Stefan H., Moelleken, Jörg, Bader, Martin, Tissot, Alain C., Tan, Seng‐Lai, Seeber, Stefan, Schett, Georg
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2015)
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Journal Article
Effect of immunisation against angiotensin II with CYT006-AngQb on ambulatory blood pressure: a double-blind, randomised, placebo-controlled phase IIa study
Tissot, Alain C, PhD, Maurer, Patrik, PhD, Nussberger, Juerg, Prof, Sabat, Robert, MD, Pfister, Thomas, PhD, Ignatenko, Stanislav, MD, Volk, Hans-Dieter, Prof, Stocker, Hans, PhD, Müller, Philipp, MD, Jennings, Gary T, PhD, Wagner, Frank, MD, Bachmann, Martin F, PhD
Published in The Lancet (British edition) (08.03.2008)
Published in The Lancet (British edition) (08.03.2008)
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Journal Article
The second-generation active Aβ immunotherapy CAD106 reduces amyloid accumulation in APP transgenic mice while minimizing potential side effects
Wiessner, Christoph, Wiederhold, Karl-Heinz, Tissot, Alain C, Frey, Peter, Danner, Simone, Jacobson, Laura H, Jennings, Gary T, Lüönd, Rainer, Ortmann, Rainer, Reichwald, Julia, Zurini, Mauro, Mir, Anis, Bachmann, Martin F, Staufenbiel, Matthias
Published in The Journal of neuroscience (22.06.2011)
Published in The Journal of neuroscience (22.06.2011)
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Journal Article
Prediction of polyspecificity from antibody sequence data by machine learning
Éliás, Szabolcs, Wrzodek, Clemens, Deane, Charlotte M, Tissot, Alain C, Klostermann, Stefan, Ros, Francesca
Published in Frontiers in bioinformatics (08.04.2024)
Published in Frontiers in bioinformatics (08.04.2024)
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Journal Article
A VLP‐based vaccine against interleukin‐1α protects mice from atherosclerosis
Tissot, Alain C., Spohn, Gunther, Jennings, Gary T., Shamshiev, Abdijapar, Kurrer, Michael O., Windak, Renata, Meier, Marco, Viesti, Miriam, Hersberger, Martin, Kündig, Thomas M., Ricci, Romeo, Bachmann, Martin F.
Published in European journal of immunology (01.03.2013)
Published in European journal of immunology (01.03.2013)
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Journal Article
Versatile virus-like particle carrier for epitope based vaccines
Tissot, Alain C, Renhofa, Regina, Schmitz, Nicole, Cielens, Indulis, Meijerink, Edwin, Ose, Velta, Jennings, Gary T, Saudan, Philippe, Pumpens, Paul, Bachmann, Martin F
Published in PloS one (23.03.2010)
Published in PloS one (23.03.2010)
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Journal Article
A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity
Ambühl, Patrice M, Tissot, Alain C, Fulurija, Alma, Maurer, Patrik, Nussberger, Juerg, Sabat, Robert, Nief, Vera, Schellekens, Charlotte, Sladko, Katja, Roubicek, Kirsten, Pfister, Thomas, Rettenbacher, Manfred, Volk, Hans-Dieter, Wagner, Frank, Müller, Philipp, Jennings, Gary T, Bachmann, Martin F
Published in Journal of hypertension (01.01.2007)
Published in Journal of hypertension (01.01.2007)
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Journal Article
Rabbits transgenic for human IgG genes recapitulating rabbit B-cell biology to generate human antibodies of high specificity and affinity
Ros, Francesca, Offner, Sonja, Klostermann, Stefan, Thorey, Irmgard, Niersbach, Helmut, Breuer, Sebastian, Zarnt, Grit, Lorenz, Stefan, Puels, Juergen, Siewe, Basile, Schueler, Nicole, Dragicevic, Tajana, Ostler, Dominique, Hansen-Wester, Imke, Lifke, Valeria, Kaluza, Brigitte, Kaluza, Klaus, van Schooten, Wim, Buelow, Roland, Tissot, Alain C, Platzer, Josef
Published in mAbs (01.01.2020)
Published in mAbs (01.01.2020)
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Journal Article
Efficient homologous prime‐boost strategies for T cell vaccination based on virus‐like particles
Schwarz, Katrin, Meijerink, Edwin, Speiser, Daniel E., Tissot, Alain C., Cielens, Indulis, Renhof, Regina, Dishlers, Andris, Pumpens, Paul, Bachmann, Martin F.
Published in European journal of immunology (01.03.2005)
Published in European journal of immunology (01.03.2005)
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Journal Article
Reply to 'Blood pressure vaccine shot down by safety concerns'
Bachmann, Martin F, Nussberger, Jürg, Tissot, Alain C, Jennings, Gary T
Published in Nature medicine (01.03.2006)
Published in Nature medicine (01.03.2006)
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Journal Article
A tumor-specific neoepitope expressed in homologous/self or heterologous/viral antigens induced comparable effector CD8+ T-cell responses by DNA vaccination
Stifter, Katja, Dekhtiarenko, Iryna, Krieger, Jana, Tissot, Alain Charles, Seufferlein, Thomas, Wagner, Martin, Schirmbeck, Reinhold
Published in Vaccine (06.05.2020)
Published in Vaccine (06.05.2020)
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Journal Article
BLOOD BRAIN BARRIER SHUTTLE
ALAIN TISSOT-DAGUETTE, JENS NIEWOEHNER, PER-OLA FRESKGARD, BERND BOHRMANN, PETER MAIER, EDUARD URICH
Year of Publication 16.01.2020
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Year of Publication 16.01.2020
Patent
Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes
Gallimore, A, Glithero, A, Godkin, A, Tissot, A C, Plückthun, A, Elliott, T, Hengartner, H, Zinkernagel, R
Published in The Journal of experimental medicine (04.05.1998)
Published in The Journal of experimental medicine (04.05.1998)
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Journal Article
Combined Inhibition of Tumor Necrosis Factor [alpha] and Interleukin-17 As a Therapeutic Opportunity in Rheumatoid Arthritis: Development and Characterization of a Novel Bispecific Antibody
Fischer, Jens A A, Hueber, Axel J, Wilson, Stacy, Galm, Margarete, Baum, Wolfgang, Kitson, Christopher, Auer, Johannes, Lorenz, Stefan H, Moelleken, Jörg, Bader, Martin, Tissot, Alain C, Tan, Seng-Lai, Seeber, Stefan, Schett, Georg
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2015)
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Journal Article
A molecular assembly system that renders antigens of choice highly repetitive for induction of protective B cell responses
Jegerlehner, Andrea, Tissot, Alain, Lechner, Franziska, Sebbel, Peter, Erdmann, Iris, Kündig, Thomas, Bächi, Thomas, Storni, Tazio, Jennings, Gary, Pumpens, Paul, Renner, Wolfgang A, Bachmann, Martin F
Published in Vaccine (19.08.2002)
Published in Vaccine (19.08.2002)
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Journal Article