Endogenous plasminogen activators mediate progressive intracerebral hemorrhage after traumatic brain injury in mice
Hijazi, Nuha, Abu Fanne, Rami, Abramovitch, Rinat, Yarovoi, Serge, Higazi, Muhamed, Abdeen, Suhair, Basheer, Maamon, Maraga, Emad, Cines, Douglas B., Al-Roof Higazi, Abd
Published in Blood (16.04.2015)
Published in Blood (16.04.2015)
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Journal Article
Alpha‐defensins: risk factor for thrombosis in COVID‐19 infection
Abdeen, Suhair, Bdeir, Khalil, Abu‐Fanne, Rami, Maraga, Emad, Higazi, Mohamed, Khurram, Nigar, Feldman, Michael, Deshpande, Charuhas, Litzky, Leslie A., Heyman, Samuel N., Montone, Kathleen T., Cines, Douglas B., Higazi, Abd Al‐Roof
Published in British Journal of Haematology (01.07.2021)
Published in British Journal of Haematology (01.07.2021)
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Journal Article
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Divergent impacts of tocilizumab and colchicine in COVID‐19‐associated coagulopathy: the role of alpha‐defensins
Abdeen, Suhair, Abu‐Fanne, Rami, Bdeir, Khalil, Maraga, Emad, Higazi, Mohamed, Cines, Douglas B., Heyman, Samuel N., Higazi, Abd Al‐Roof
Published in British journal of haematology (01.02.2022)
Published in British journal of haematology (01.02.2022)
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Journal Article
The plasminogen activator system: involvement in central nervous system inflammation and a potential site for therapeutic intervention
Gur-Wahnon, Devorah, Mizrachi, Tehila, Maaravi-Pinto, Florence-Yehudith, Lourbopoulos, Athanasis, Grigoriadis, Nikolaos, Higazi, Abd-Al Roof, Brenner, Talma
Published in Journal of neuroinflammation (11.10.2013)
Published in Journal of neuroinflammation (11.10.2013)
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Journal Article
Characterization of metabolic alterations in the lean metabolically unhealthy alpha defensin transgenic mice
Higazi, Abd Al-Roof, Maraga, Emad, Baraghithy, Saja, Udi, Shiran, Azar, Shahar, Saada, Ann, Glaser, Benjamin, Avrahami, Dana, Abdeen, Suhair, Hamdan, Zenab, Tam, Joseph, Fanne, Rami Abu
Published in iScience (16.02.2024)
Published in iScience (16.02.2024)
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Journal Article
Opposing effects of HNP1 (α-defensin-1) on plasma cholesterol and atherogenesis
Higazi, Mohamed, Abdeen, Suhair, Abu-Fanne, Rami, Heyman, Samuel N, Masarwy, Aseel, Bdeir, Khalil, Maraga, Emad, Cines, Douglas B, Higazi, Abd Al-Roof
Published in PloS one (17.04.2020)
Published in PloS one (17.04.2020)
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Journal Article
Alleviation of Hepatic Steatosis by Alpha-Defensin Is Associated with Enhanced Lipolysis
Maraga, Emad, Safadi, Rifaat, Amer, Johnny, Higazi, Abd Al-Roof, Fanne, Rami Abu
Published in Medicina (Kaunas, Lithuania) (19.05.2023)
Published in Medicina (Kaunas, Lithuania) (19.05.2023)
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Journal Article
Blood–brain barrier permeability and tPA-mediated neurotoxicity
Fanne, Rami Abu, Nassar, Taher, Yarovoi, Sergei, Rayan, Anwar, Lamensdorf, Itschak, Karakoveski, Michael, Vadim, Polianski, Jammal, Mahmud, Cines, Douglas B., Al-Roof Higazi, Abd
Published in Neuropharmacology (01.06.2010)
Published in Neuropharmacology (01.06.2010)
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Journal Article
Insulin and glucagon share the same mechanism of neuroprotection in diabetic rats: role of glutamate
Fanne, Rami Abu, Nassar, Taher, Heyman, Samuel N, Hijazi, Nuha, Higazi, Abd Al-Roof
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.09.2011)
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01.09.2011)
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Journal Article
Regulation of neovascularization by human neutrophil peptides (alpha-defensins): a link between inflammation and angiogenesis
Chavakis, Triantafyllos, Cines, Douglas B, Rhee, Joong-Sup, Liang, Olin D, Schubert, Uwe, Hammes, Hans-Peter, Higazi, Abd Al-Roof, Nawroth, Peter P, Preissner, Klaus T, Bdeir, Khalil
Published in The FASEB journal (01.08.2004)
Published in The FASEB journal (01.08.2004)
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Journal Article
Neutrophil α-Defensins Cause Lung Injury by Disrupting the Capillary-Epithelial Barrier
BDEIR, Khalil, AL-ROOF HIGAZI, Abd, KULIKOVSKAYA, Irina, CHRISTOFIDOU-SOLOMIDOU, Melpo, VINOGRADOV, Sergei A, ALLEN, Timothy C, IDELL, Steven, LINZMEIER, Rose, GANZ, Tomas, CINES, Douglas B
Published in American journal of respiratory and critical care medicine (01.05.2010)
Published in American journal of respiratory and critical care medicine (01.05.2010)
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Journal Article
The fibrinolytic system attenuates vascular tone: effects of tissue plasminogen activator (tPA) and aminocaproic acid on renal microcirculation
Heyman, Samuel N, Hanna, Zohair, Nassar, Taher, Shina, Ahuva, Akkawi, Sa'ed, Goldfarb, Marina, Rosen, Seymour, Higazi, Abd‐Al Roof
Published in British journal of pharmacology (01.03.2004)
Published in British journal of pharmacology (01.03.2004)
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Journal Article
Urokinase-type Plasminogen Activator (uPA) Induces Pulmonary Microvascular Endothelial Permeability through Low Density Lipoprotein Receptor-related Protein (LRP)-dependent Activation of Endothelial Nitric-oxide Synthase
Makarova, Anastasia M., Lebedeva, Tatiana V., Nassar, Taher, Higazi, Abd Al-Roof, Xue, Jing, Carinato, Maria E., Bdeir, Khalil, Cines, Douglas B., Stepanova, Victoria
Published in The Journal of biological chemistry (01.07.2011)
Published in The Journal of biological chemistry (01.07.2011)
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Journal Article
Neutralizing the neurotoxic effects of exogenous and endogenous tPA
Armstead, William M, Nassar, Taher, Akkawi, Saed, Smith, Douglas H, Chen, Xiao-Han, Cines, Douglas B, Higazi, Abd Al-Roof
Published in Nature neuroscience (01.09.2006)
Published in Nature neuroscience (01.09.2006)
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Journal Article
In vitro and in vivo effects of tPA and PAI-1 on blood vessel tone
Nassar, Taher, Akkawi, Sa’ed, Shina, Ahuva, Haj-Yehia, Abdullah, Bdeir, Khalil, Tarshis, Mark, Heyman, Samuel N., Higazi, Abd Al-Roof
Published in Blood (01.02.2004)
Published in Blood (01.02.2004)
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Journal Article
Platelet Factor 4 Enhances the Binding of Oxidized Low-density Lipoprotein to Vascular Wall Cells
Nassar, Taher, Sachais, Bruce S, Akkawi, Sa'ed, Kowalska, Maria Anna, Bdeir, Khalil, Leitersdorf, Eran, Hiss, Edna, Ziporen, Leah, Aviram, Michael, Cines, Douglas, Poncz, Mortimer, Higazi, Abd Al-Roof
Published in The Journal of biological chemistry (21.02.2003)
Published in The Journal of biological chemistry (21.02.2003)
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Journal Article
ACE2, COVID-19 Infection, Inflammation, and Coagulopathy: Missing Pieces in the Puzzle
Abassi, Zaid, Higazi, Abd Al Roof, Kinaneh, Safa, Armaly, Zaher, Skorecki, Karl, Heyman, Samuel N
Published in Frontiers in physiology (06.10.2020)
Published in Frontiers in physiology (06.10.2020)
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Journal Article
Release of IL-6 After Stroke Contributes to Impaired Cerebral Autoregulation and Hippocampal Neuronal Necrosis Through NMDA Receptor Activation and Upregulation of ET-1 and JNK
Armstead, William M., Hekierski, Hugh, Pastor, Philip, Yarovoi, Serge, Higazi, Abd Al-Roof, Cines, Douglas B.
Published in Translational stroke research (01.02.2019)
Published in Translational stroke research (01.02.2019)
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Journal Article
Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic itinerary, resulting in retention of low-density lipoprotein on the cell surface
Sachais, Bruce S., Kuo, Alice, Nassar, Taher, Morgan, Jeanelle, Kariko, Katalin, Williams, Kevin Jon, Feldman, Michael, Aviram, Michael, Shah, Neelima, Jarett, Leonard, Poncz, Mortimer, Cines, Douglas B., Higazi, Abd Al-Roof
Published in Blood (15.05.2002)
Published in Blood (15.05.2002)
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