Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi)
Gu, Jessie, Noe, Adele, Chandra, Priya, Al-Fayoumi, Suliman, Ligueros-Saylan, Monica, Sarangapani, Ramesh, Maahs, Suzanne, Ksander, Gary, Rigel, Dean F, Jeng, Arco Y, Lin, Tsu-Han, Zheng, Weiyi, Dole, William P
Published in Journal of clinical pharmacology (01.04.2010)
Published in Journal of clinical pharmacology (01.04.2010)
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Journal Article
Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy
Singer, Jack W, Fleischman, Angela, Al-Fayoumi, Suliman, Mascarenhas, John O, Yu, Qiang, Agarwal, Anupriya
Published in Oncotarget (07.09.2018)
Published in Oncotarget (07.09.2018)
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Journal Article
Comparative phenotypic profiling of the JAK2 inhibitors ruxolitinib, fedratinib, momelotinib, and pacritinib reveals distinct mechanistic signatures
Singer, Jack W, Al-Fayoumi, Suliman, Taylor, Jason, Velichko, Sharlene, O'Mahony, Alison
Published in PloS one (27.09.2019)
Published in PloS one (27.09.2019)
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Journal Article
Phase 1/2 study of pacritinib, a next generation JAK2/FLT3 inhibitor, in myelofibrosis or other myeloid malignancies
Verstovsek, Srdan, Odenike, Olatoyosi, Singer, Jack W, Granston, Tanya, Al-Fayoumi, Suliman, Deeg, H Joachim
Published in Journal of hematology and oncology (08.12.2016)
Published in Journal of hematology and oncology (08.12.2016)
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Journal Article
Pharmacokinetics and pharmacodynamics of dexamethasone sodium-m-sulfobenzoate (DS) after intravenous and intramuscular administration: a comparison with dexamethasone phosphate (DP)
Hochhaus, G, Barth, J, al-Fayoumi, S, Suarez, S, Derendorf, H, Hochhaus, R, Möllmann, H
Published in Journal of clinical pharmacology (01.04.2001)
Published in Journal of clinical pharmacology (01.04.2001)
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Journal Article
Abstract 10372: A Clinical Drug-Drug Interaction Study of Imb-1018972, a Novel Investigational Cardiac Mitotrope in Phase 2 Development for the Treatment of Myocardial Ischemia and Hypertrophic Cardiomyopathy
Tremaine, Larry, Al-Fayoumi, Suliman, van de Wetering, Jeroen, van Iersel, Thjis, Patel, Jaikrishna, Chamberlin, Paul
Published in Circulation (New York, N.Y.) (16.11.2021)
Published in Circulation (New York, N.Y.) (16.11.2021)
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Journal Article
Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial
Mascarenhas, John, Hoffman, Ronald, Talpaz, Moshe, Gerds, Aaron T, Stein, Brady, Gupta, Vikas, Szoke, Anita, Drummond, Mark, Pristupa, Alexander, Granston, Tanya, Daly, Robert, Al-Fayoumi, Suliman, Callahan, Jennifer A, Singer, Jack W, Gotlib, Jason, Jamieson, Catriona, Harrison, Claire, Mesa, Ruben, Verstovsek, Srdan
Published in JAMA oncology (01.05.2018)
Published in JAMA oncology (01.05.2018)
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Journal Article
Thorough QT Analysis of a Single Dose of Pacritinib: Results of the PAC107 Study
Buckley, Sarah, Al-Fayoumi, Suliman, Wang, Lixia, Dean, James, Suthar, Purvi, Kaufmann, Priska
Published in Clinical lymphoma, myeloma and leukemia (01.09.2024)
Published in Clinical lymphoma, myeloma and leukemia (01.09.2024)
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Journal Article
Identification of stabilized dynorphin derivatives for suppressing tolerance in morphine-dependent rats
Al-Fayoumi, Suliman I, Brugos, Boglarka, Arya, Vikram, Mulder, Esther, Eppler, Barbel, Mauderli, Andre P, Hochhaus, Günther
Published in Pharmaceutical research (01.08.2004)
Published in Pharmaceutical research (01.08.2004)
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Journal Article
AI & experimental-based discovery and preclinical IND-enabling studies of selective BMX inhibitors for development of cancer therapeutics
Elsanhoury, Rwan, Alasmari, Abdulaziz, Parupathi, Prashanth, Jumaa, Mouhannad, Al-Fayoumi, Suliman, Kumar, Avinash, Khashan, Raed, Nazzal, Sami, Fayyad, Ahmed Abu
Published in International journal of pharmaceutics (15.10.2023)
Published in International journal of pharmaceutics (15.10.2023)
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Journal Article
Phase 1, dose-ranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers
Kubota, Ryo, Al-Fayoumi, Suliman, Mallikaarjun, Suresh, Patil, Shiva, Bavik, Claes, Chandler, John W
Published in Retina (Philadelphia, Pa.) (01.03.2014)
Published in Retina (Philadelphia, Pa.) (01.03.2014)
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Journal Article
Abstract CT159: Investigation of the absorption, metabolism, excretion, and mass balance of 14C-pacritinib in healthy subjects: a phase I study
Al-Fayoumi, Suliman, Amberg, Sherri, Zhou, Huafeng, Millard, Lindsey, Singer, Jack W, Dean, James P
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Abstract CT159: Investigation of the absorption, metabolism, excretion, and mass balance of [14C]-pacritinib in healthy subjects: a phase I study
Al-Fayoumi, Suliman, Amberg, Sherri, Zhou, Huafeng, Millard, Lindsey, Singer, Jack W., Dean, James P.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Clinical Pharmacology Profile of Pacritinib (PAC), a Novel JAK2/FLT3 Inhibitor
Al-Fayoumi, Suliman, Campbell, Mary S., Amberg, Sherri, Zhou, Huafeng, Millard, Lindsey, Dean, James P.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
Comprehensive Kinase Profile of Pacritinib, a Non-Myelosuppressive JAK2 Kinase Inhibitor in Phase 3 Development in Primary and Post ET/PV Myelofibrosis
Singer, Jack, Al-Fayoumi, Suliman, Ma, Haiching, Komrokji, Rami S, Mesa, Ruben, Verstovsek, Srdan
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Tolerability and toxicological profile of pixantrone (Pixuvri®) in juvenile mice. Comparative study with doxorubicin
Longo, Monica, Torre, Paola Della, Allievi, Cecilia, Morisetti, Alberto, Al-Fayoumi, Suliman, Singer, Jack W.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.07.2014)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.07.2014)
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Journal Article