A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude
Doruk, Yagmur Umay, Yarparvar, Darya, Akyel, Yasemin Kubra, Gul, Seref, Taskin, Ali Cihan, Yilmaz, Fatma, Baris, Ibrahim, Ozturk, Nuri, Türkay, Metin, Ozturk, Narin, Okyar, Alper, Kavakli, Ibrahim Halil
Published in The Journal of biological chemistry (13.03.2020)
Published in The Journal of biological chemistry (13.03.2020)
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Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice
Gul, Seref, Akyel, Yasemin Kubra, Gul, Zeynep Melis, Isin, Safak, Ozcan, Onur, Korkmaz, Tuba, Selvi, Saba, Danis, Ibrahim, Ipek, Ozgecan Savlug, Aygenli, Fatih, Taskin, Ali Cihan, Akarlar, Büşra Aytül, Ozlu, Nurhan, Ozturk, Nuri, Ozturk, Narin, Ünal, Durişehvar Özer, Guzel, Mustafa, Turkay, Metin, Okyar, Alper, Kavakli, Ibrahim Halil
Published in Nature communications (08.11.2022)
Published in Nature communications (08.11.2022)
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Journal Article
The association of ABCC5 and ABCC11 polymorphisms with the pharmacokinetics of 5-FU in advanced gastric cancer patients
PALA KARA, Zeliha, OZTAS, Ezgi, OZTURK, Dilek, AKYEL, Yasemin, TURNA, Zeynep, OKYAR, Alper, ÖZHAN, Gül
Published in Clinical and experimental health sciences (Online) (01.09.2020)
Published in Clinical and experimental health sciences (Online) (01.09.2020)
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Journal Article
Circadian Dysfunction in Adipose Tissue: Chronotherapy in Metabolic Diseases
Civelek, Erkan, Ozturk Civelek, Dilek, Akyel, Yasemin Kubra, Kaleli Durman, Deniz, Okyar, Alper
Published in Biology (Basel, Switzerland) (01.08.2023)
Published in Biology (Basel, Switzerland) (01.08.2023)
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Journal Article
The role of the circadian timing system on drug metabolism and detoxification: an update
Okyar, Alper, Ozturk Civelek, Dilek, Akyel, Yasemin Kubra, Surme, Saliha, Pala Kara, Zeliha, Kavakli, I Halil
Published in Expert opinion on drug metabolism & toxicology (02.06.2024)
Published in Expert opinion on drug metabolism & toxicology (02.06.2024)
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Dosing-time, feeding, and sex-dependent variations of everolimus pharmacokinetics in mice
Ozturk Civelek, Dilek, Ozturk Seyhan, Narin, Akyel, Yasemin Kubra, Gazioglu, Isil, Pala Kara, Zeliha, Orman, Mehmet N, Okyar, Alper
Published in Fundamental & clinical pharmacology (18.03.2024)
Published in Fundamental & clinical pharmacology (18.03.2024)
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Journal Article
TW68, cryptochromes stabilizer, regulates fasting blood glucose levels in diabetic ob/ob and high fat-diet-induced obese mice
Surme, Saliha, Ergun, Cagla, Gul, Seref, Akyel, Yasemin Kubra, Gul, Zeynep Melis, Ozcan, Onur, Ipek, Ozgecan Savlug, Akarlar, Busra Aytul, Ozlu, Nurhan, Taskin, Ali Cihan, Turkay, Metin, Gören, Ahmet Ceyhan, Baris, Ibrahim, Ozturk, Nuri, Guzel, Mustafa, Aydin, Cihan, Okyar, Alper, Kavakli, Ibrahim Halil
Published in Biochemical pharmacology (01.12.2023)
Published in Biochemical pharmacology (01.12.2023)
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Journal Article
Diurnal Changes in Capecitabine Clock-Controlled Metabolism Enzymes Are Responsible for Its Pharmacokinetics in Male Mice
Akyel, Yasemin Kubra, Ozturk Civelek, Dilek, Ozturk Seyhan, Narin, Gul, Seref, Gazioglu, Isil, Pala Kara, Zeliha, Lévi, Francis, Kavakli, Ibrahim Halil, Okyar, Alper
Published in Journal of biological rhythms (01.04.2023)
Published in Journal of biological rhythms (01.04.2023)
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Pharmacist’s Role in Pharmacotherapeutic Management of Alzheimer’s Disease
Carcak Yilmaz, Nihan, Altuntas, Merve, Akyel, Y. Kubra, Uydes Dogan, B. Sonmez
Published in Istanbul journal of pharmacy (01.06.2017)
Published in Istanbul journal of pharmacy (01.06.2017)
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