GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab
Kato, Daiki, Yaguchi, Tomonori, Iwata, Takashi, Katoh, Yuki, Morii, Kenji, Tsubota, Kinya, Takise, Yoshiaki, Tamiya, Masaki, Kamada, Haruhiko, Akiba, Hiroki, Tsumoto, Kouhei, Serada, Satoshi, Naka, Tetsuji, Nishimura, Ryohei, Nakagawa, Takayuki, Kawakami, Yutaka
Published in eLife (31.03.2020)
Published in eLife (31.03.2020)
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Journal Article
Novel neutralizing human monoclonal antibodies against tetanus neurotoxin
Minamitani, Takeharu, Kiyose, Karin, Otsubo, Ryota, Ito, Toshihiro, Akiba, Hiroki, Furuta, Rika A., Inoue, Tsuyoshi, Tsumoto, Kouhei, Satake, Masahiro, Yasui, Teruhito
Published in Scientific reports (09.06.2021)
Published in Scientific reports (09.06.2021)
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Journal Article
Epitope-dependent thermodynamic signature of single-domain antibodies against hen egg lysozyme
Akiba, Hiroki, Tamura, Hiroko, Caaveiro, Jose M M, Tsumoto, Kouhei
Published in Journal of biochemistry (Tokyo) (01.11.2021)
Published in Journal of biochemistry (Tokyo) (01.11.2021)
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Journal Article
Optimization of anti-ADAMTS13 antibodies for the treatment of ADAMTS13-related bleeding disorder in patients receiving circulatory assist device support
Ito, Toshihiro, Minamitani, Takeharu, Hayakawa, Masaki, Otsubo, Ryota, Akiba, Hiroki, Tsumoto, Kouhei, Matsumoto, Masanori, Yasui, Teruhito
Published in Scientific reports (16.11.2021)
Published in Scientific reports (16.11.2021)
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Journal Article
111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis
Fujiwara, Kentaro, Tsuji, Atsushi B., Sudo, Hitomi, Sugyo, Aya, Akiba, Hiroki, Iwanari, Hiroko, Kusano-Arai, Osamu, Tsumoto, Kouhei, Momose, Toshimitsu, Hamakubo, Takao, Higashi, Tatsuya
Published in Annals of nuclear medicine (01.01.2020)
Published in Annals of nuclear medicine (01.01.2020)
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Journal Article
Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody
Miyanabe, Kazuhiro, Akiba, Hiroki, Kuroda, Daisuke, Nakakido, Makoto, Kusano-Arai, Osamu, Iwanari, Hiroko, Hamakubo, Takao, Caaveiro, Jose M M, Tsumoto, Kouhei
Published in Journal of biochemistry (Tokyo) (01.07.2018)
Published in Journal of biochemistry (Tokyo) (01.07.2018)
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Journal Article
Use of SpyTag/SpyCatcher to construct bispecific antibodies that target two epitopes of a single antigen
Yumura, Kyohei, Akiba, Hiroki, Nagatoishi, Satoru, Kusano-Arai, Osamu, Iwanari, Hiroko, Hamakubo, Takao, Tsumoto, Kouhei
Published in Journal of biochemistry (Tokyo) (01.09.2017)
Published in Journal of biochemistry (Tokyo) (01.09.2017)
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Journal Article
Roles of the disulfide bond between the variable and the constant domains of rabbit immunoglobulin kappa chains in thermal stability and affinity
Kawade, Raiji, Akiba, Hiroki, Entzminger, Kevin, Maruyama, Toshiaki, Okumura, C J, Tsumoto, Kouhei
Published in Protein engineering, design and selection (01.07.2018)
Published in Protein engineering, design and selection (01.07.2018)
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Journal Article
Generation of biparatopic antibody through two-step targeting of fragment antibodies on antigen using SpyTag and SpyCatcher
Akiba, Hiroki, Takayanagi, Kensuke, Kusano-Arai, Osamu, Iwanari, Hiroko, Hamakubo, Takao, Tsumoto, Kouhei
Published in Biotechnology reports (Amsterdam, Netherlands) (01.03.2020)
Published in Biotechnology reports (Amsterdam, Netherlands) (01.03.2020)
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Journal Article
Tyrosine Sulfation Restricts the Conformational Ensemble of a Flexible Peptide, Strengthening the Binding Affinity for an Antibody
Miyanabe, Kazuhiro, Yamashita, Takefumi, Abe, Yoshito, Akiba, Hiroki, Takamatsu, Yuichiro, Nakakido, Makoto, Hamakubo, Takao, Ueda, Tadashi, Caaveiro, Jose M. M, Tsumoto, Kouhei
Published in Biochemistry (Easton) (17.07.2018)
Published in Biochemistry (Easton) (17.07.2018)
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Journal Article
Thermodynamic analyses of amino acid residues at the interface of an antibody B2212A and its antigen roundabout homolog 1
Yui, Anna, Akiba, Hiroki, Kudo, Shota, Nakakido, Makoto, Nagatoishi, Satoru, Tsumoto, Kouhei
Published in Journal of biochemistry (Tokyo) (01.10.2017)
Published in Journal of biochemistry (Tokyo) (01.10.2017)
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Journal Article
Binuclear Terbium(III) Complex as a Probe for Tyrosine Phosphorylation
Akiba, Hiroki, Sumaoka, Jun, Komiyama, Makoto
Published in Chemistry : a European journal (03.05.2010)
Published in Chemistry : a European journal (03.05.2010)
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Journal Article
Structural behavior of keratin-associated protein 8.1 in human hair as revealed by a monoclonal antibody
Akiba, Hiroki, Ikeuchi, Emina, Ganbat, Javkhlan, Fujikawa, Hiroki, Arai-Kusano, Osamu, Iwanari, Hiroko, Nakakido, Makoto, Hamakubo, Takao, Shimomura, Yutaka, Tsumoto, Kouhei
Published in Journal of structural biology (01.11.2018)
Published in Journal of structural biology (01.11.2018)
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Journal Article
Improved Brain Expression of Anti-Amyloid β scFv by Complexation of mRNA Including a Secretion Sequence with PEG-based Block Catiomer
Perche, Federico, Uchida, Satoshi, Akiba, Hiroki, Lin, Chin-Yu, Ikegami, Masaru, Dirisala, Anjaneyulu, Nakashima, Toshihiro, Itaka, Keiji, Tsumoto, Kohei, Kataoka, Kazunori
Published in Current Alzheimer research (01.03.2017)
Published in Current Alzheimer research (01.03.2017)
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Journal Article
Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection
Akiba, Hiroki, Fujita, Junso, Ise, Tomoko, Nishiyama, Kentaro, Miyata, Tomoko, Kato, Takayuki, Namba, Keiichi, Ohno, Hiroaki, Kamada, Haruhiko, Nagata, Satoshi, Tsumoto, Kouhei
Published in Communications biology (27.09.2023)
Published in Communications biology (27.09.2023)
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