Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS
Hodges, Timothy R, Abbott, Jason R, Little, Andrew J, Sarkar, Dhruba, Salovich, James M, Howes, Jennifer E, Akan, Denis T, Sai, Jiqing, Arnold, Allison L, Browning, Carrie, Burns, Michael C, Sobolik, Tammy, Sun, Qi, Beesetty, Yugandhar, Coker, Jesse A, Scharn, Dirk, Stadtmueller, Heinz, Rossanese, Olivia W, Phan, Jason, Waterson, Alex G, McConnell, Darryl B, Fesik, Stephen W
Published in Journal of medicinal chemistry (11.10.2018)
Published in Journal of medicinal chemistry (11.10.2018)
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Journal Article
The Plasma Pencil: A Source of Hypersonic Cold Plasma Bullets for Biomedical Applications
Laroussi, M., Hynes, W., Akan, T., Xinpei Lu, Tendero, C.
Published in IEEE transactions on plasma science (01.08.2008)
Published in IEEE transactions on plasma science (01.08.2008)
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Journal Article
Cutaneous mastocytosis: demographic aspects and clinical features of 55 patients
Akoglu, G, Erkin, G, Cakir, B, Boztepe, G, Sahin, S, Karaduman, A, Atakan, N, Akan, T, Kolemen, F
Published in Journal of the European Academy of Dermatology and Venereology (01.09.2006)
Published in Journal of the European Academy of Dermatology and Venereology (01.09.2006)
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Journal Article
Determination of Exchange Coupling of Dimethoxo-Bridged Dichromium(III) Complexes and Magnetic Field Dependence of Magnetization
Isik, F., Sabaner, M. A., Akan, A. T., Bayri, A.
Published in Journal of superconductivity and novel magnetism (01.04.2013)
Published in Journal of superconductivity and novel magnetism (01.04.2013)
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Journal Article
Conference Proceeding
Small Molecule-Mediated Activation of RAS Elicits Biphasic Modulation of Phospho-ERK Levels that Are Regulated through Negative Feedback on SOS1
Howes, Jennifer E, Akan, Denis T, Burns, Michael C, Rossanese, Olivia W, Waterson, Alex G, Fesik, Stephen W
Published in Molecular cancer therapeutics (01.05.2018)
Published in Molecular cancer therapeutics (01.05.2018)
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Journal Article
Discovery of Aminopiperidine Indoles That Activate the Guanine Nucleotide Exchange Factor SOS1 and Modulate RAS Signaling
Abbott, Jason R, Hodges, Timothy R, Daniels, R. Nathan, Patel, Pratiq A, Kennedy, J. Phillip, Howes, Jennifer E, Akan, Denis T, Burns, Michael C, Sai, Jiqing, Sobolik, Tammy, Beesetty, Yugandhar, Lee, Taekyu, Rossanese, Olivia W, Phan, Jason, Waterson, Alex G, Fesik, Stephen W
Published in Journal of medicinal chemistry (26.07.2018)
Published in Journal of medicinal chemistry (26.07.2018)
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Journal Article
MgB2 superconducting thin films sequentially fabricated using DC magnetron sputtering and thermionic vacuum arc method
OKUR, S, KALKANCI, M, PAT, S, EKEM, N, AKAN, T, BALBAG, Z, MUSA, G, TANOGLU, M
Published in Physica. C, Superconductivity (01.11.2007)
Published in Physica. C, Superconductivity (01.11.2007)
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Journal Article
Boron thin film deposition by using Thermionic Vacuum Arc (TVA) technology
Akan, T., Ekem, N., Pat, S., Issever, U.G., Balbag, M.Z., Cenik, M.I., Vladoiu, R., Musa, G.
Published in Materials letters (2007)
Published in Materials letters (2007)
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Journal Article
Small Molecule SOS1 Agonists Modulate MAPK and PI3K Signaling via Independent Cellular Responses
Akan, Denis T, Howes, Jennifer E, Sai, Jiqing, Arnold, Allison L, Beesetty, Yugandhar, Phan, Jason, Olejniczak, Edward T, Waterson, Alex G, Fesik, Stephen W
Published in ACS chemical biology (15.03.2019)
Published in ACS chemical biology (15.03.2019)
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Journal Article
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on RAS
Abbott, Jason R, Patel, Pratiq A, Howes, Jennifer E, Akan, Denis T, Kennedy, J. Phillip, Burns, Michael C, Browning, Carrie F, Sun, Qi, Rossanese, Olivia W, Phan, Jason, Waterson, Alex G, Fesik, Stephen W
Published in ACS medicinal chemistry letters (13.09.2018)
Published in ACS medicinal chemistry letters (13.09.2018)
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Journal Article
Boron evaporation and related difficulties
Balbag, M Z, Pat, S, Cenik, M I, Akan, T, Ekem, N, Musa, G
Published in Journal of Optoelectronics and Advanced Materials (01.04.2007)
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Published in Journal of Optoelectronics and Advanced Materials (01.04.2007)
Journal Article
Characteristics of boron thin films obtained by TVA technology
Musa, G, Vladoiu, R, Ciupina, V, Lungu, C P, Mustata, I, Pat, S, Akan, T, Ekem, N
Published in Journal of Optoelectronics and Advanced Materials (01.04.2006)
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Published in Journal of Optoelectronics and Advanced Materials (01.04.2006)
Journal Article
Titanium oxidation by pulsed oxygen plasma
Balbag, M Z, Pat, S, Cenik, I, Ekem, N, Akan, T, Baksan, B, Vladoiu, R, Musa, G
Published in Journal of Optoelectronics and Advanced Materials (01.03.2008)
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Published in Journal of Optoelectronics and Advanced Materials (01.03.2008)
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Carbon synthesis in methane plasma
Musa, G, Ekem, N, Path, S, Balbag, M Z, Cenik, M I, Akan, T, Ciupina, V, Vladoiu, R, Tanisli, M, Ozen, O
Published in Journal of Optoelectronics and Advanced Materials (01.04.2007)
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Published in Journal of Optoelectronics and Advanced Materials (01.04.2007)
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Kindler syndrome: Absence of definite ultrastructural feature
Şentürk, Nilgün, Usubütün, Alp, Şahin, Sedef, Bükülmez, Gül, Erkek, Emel, Topaloğlu, Rezan, Akan, Tülin
Published in Journal of the American Academy of Dermatology (01.02.1999)
Published in Journal of the American Academy of Dermatology (01.02.1999)
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Journal Article
P138 Hormonal parameters in androgenetic alopecia of the male
Güleç, T.O., Akan, T., Karaduman, A.
Published in Journal of the European Academy of Dermatology and Venereology (01.09.1997)
Published in Journal of the European Academy of Dermatology and Venereology (01.09.1997)
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Journal Article
P106 Serum adenosine deaminase levels in psoriatic patients
Bükülmez, G., Akan, T., Karaduman, A., Ciliv, G.
Published in Journal of the European Academy of Dermatology and Venereology (01.09.1997)
Published in Journal of the European Academy of Dermatology and Venereology (01.09.1997)
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Journal Article
Abstract PR04: Small molecule-mediated activation of Ras elicits inhibition of MAPK and PI3K signaling though pathway feedback
Howes, Jennifer E., Akan, Denis T., Alicie, Bethany M., Waterson, Alex G., Rossanese, Olivia W., Fesik, Stephen W.
Published in Clinical cancer research (01.01.2017)
Published in Clinical cancer research (01.01.2017)
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