Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson’s disease
Ren, Qian, Ma, Min, Yang, Jun, Nonaka, Risa, Yamaguchi, Akihiro, Ishikawa, Kei-ichi, Kobayashi, Kenta, Murayama, Shigeo, Hwang, Sung Hee, Saiki, Shinji, Akamatsu, Wado, Hattori, Nobutaka, Hammock, Bruce D., Hashimoto, Kenji
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (19.06.2018)
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Increased l1 retrotransposition in the neuronal genome in schizophrenia
Bundo, Miki, Toyoshima, Manabu, Okada, Yohei, Akamatsu, Wado, Ueda, Junko, Nemoto-Miyauchi, Taeko, Sunaga, Fumiko, Toritsuka, Michihiro, Ikawa, Daisuke, Kakita, Akiyoshi, Kato, Motoichiro, Kasai, Kiyoto, Kishimoto, Toshifumi, Nawa, Hiroyuki, Okano, Hideyuki, Yoshikawa, Takeo, Kato, Tadafumi, Iwamoto, Kazuya
Published in Neuron (Cambridge, Mass.) (22.01.2014)
Published in Neuron (Cambridge, Mass.) (22.01.2014)
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Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development
Popovitchenko, Tatiana, Park, Yongkyu, Page, Nicholas F, Luo, Xiaobing, Krsnik, Zeljka, Liu, Yuan, Salamon, Iva, Stephenson, Jessica D, Kraushar, Matthew L, Volk, Nicole L, Patel, Sejal M, Wijeratne, H R Sagara, Li, Diana, Suthar, Kandarp S, Wach, Aaron, Sun, Miao, Arnold, Sebastian J, Akamatsu, Wado, Okano, Hideyuki, Paillard, Luc, Zhang, Huaye, Buyske, Steven, Kostovic, Ivica, De Rubeis, Silvia, Hart, Ronald P, Rasin, Mladen-Roko
Published in Nature communications (03.04.2020)
Published in Nature communications (03.04.2020)
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Variants in saposin D domain of prosaposin gene linked to Parkinson's disease
Oji, Yutaka, Hatano, Taku, Ueno, Shin-Ichi, Funayama, Manabu, Ishikawa, Kei-Ichi, Okuzumi, Ayami, Noda, Sachiko, Sato, Shigeto, Satake, Wataru, Toda, Tatsushi, Li, Yuanzhe, Hino-Takai, Tomoko, Kakuta, Soichiro, Tsunemi, Taiji, Yoshino, Hiroyo, Nishioka, Kenya, Hattori, Tatsuya, Mizutani, Yasuaki, Mutoh, Tatsuro, Yokochi, Fusako, Ichinose, Yuta, Koh, Kishin, Shindo, Kazumasa, Takiyama, Yoshihisa, Hamaguchi, Tsuyoshi, Yamada, Masahito, Farrer, Matthew J, Uchiyama, Yasuo, Akamatsu, Wado, Wu, Yih-Ru, Matsuda, Junko, Hattori, Nobutaka
Published in Brain (London, England : 1878) (01.04.2020)
Published in Brain (London, England : 1878) (01.04.2020)
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Neuroprotective effects of memantine via enhancement of autophagy
Hirano, Kazuoki, Fujimaki, Motoki, Sasazawa, Yukiko, Yamaguchi, Akihiro, Ishikawa, Kei-Ichi, Miyamoto, Kengo, Souma, Sanae, Furuya, Norihiko, Imamichi, Yoko, Yamada, Daisuke, Saya, Hideyuki, Akamatsu, Wado, Saiki, Shinji, Hattori, Nobutaka
Published in Biochemical and biophysical research communications (08.10.2019)
Published in Biochemical and biophysical research communications (08.10.2019)
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BRUP‐1, an intracellular bilirubin modulator, exerts neuroprotective activity in a cellular Parkinson’s disease model
Kataura, Tetsushi, Saiki, Shinji, Ishikawa, Kei‐ichi, Akamatsu, Wado, Sasazawa, Yukiko, Hattori, Nobutaka, Imoto, Masaya
Published in Journal of neurochemistry (01.10.2020)
Published in Journal of neurochemistry (01.10.2020)
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Regeneration of the damaged central nervous system through reprogramming technology: Basic concepts and potential application for cell replacement therapy
Matsui, Takeshi, Akamatsu, Wado, Nakamura, Masaya, Okano, Hideyuki
Published in Experimental neurology (01.10.2014)
Published in Experimental neurology (01.10.2014)
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Generation of hiPSCs (JUCGRMi003-A) from a patient with Parkinson’s disease with PARK2 mutation
Ishikawa, Kei-ichi, Okuzumi, Ayami, Yoshino, Hiroyo, Hattori, Nobutaka, Akamatsu, Wado
Published in Stem cell research (01.04.2024)
Published in Stem cell research (01.04.2024)
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Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons
Suzuki, Sadafumi, Akamatsu, Wado, Kisa, Fumihiko, Sone, Takefumi, Ishikawa, Kei-ichi, Kuzumaki, Naoko, Katayama, Hiroyuki, Miyawaki, Atsushi, Hattori, Nobutaka, Okano, Hideyuki
Published in Biochemical and biophysical research communications (29.01.2017)
Published in Biochemical and biophysical research communications (29.01.2017)
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Escape from Pluripotency via Inhibition of TGF-β/BMP and Activation of Wnt Signaling Accelerates Differentiation and Aging in hPSC Progeny Cells
Fujimori, Koki, Matsumoto, Takuya, Kisa, Fumihiko, Hattori, Nobutaka, Okano, Hideyuki, Akamatsu, Wado
Published in Stem cell reports (14.11.2017)
Published in Stem cell reports (14.11.2017)
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Controlling the Regional Identity of hPSC-Derived Neurons to Uncover Neuronal Subtype Specificity of Neurological Disease Phenotypes
Imaizumi, Kent, Sone, Takefumi, Ibata, Keiji, Fujimori, Koki, Yuzaki, Michisuke, Akamatsu, Wado, Okano, Hideyuki
Published in Stem cell reports (08.12.2015)
Published in Stem cell reports (08.12.2015)
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CHARGE syndrome modeling using patient-iPSCs reveals defective migration of neural crest cells harboring CHD7 mutations
Okuno, Hironobu, Renault Mihara, Francois, Ohta, Shigeki, Fukuda, Kimiko, Kurosawa, Kenji, Akamatsu, Wado, Sanosaka, Tsukasa, Kohyama, Jun, Hayashi, Kanehiro, Nakajima, Kazunori, Takahashi, Takao, Wysocka, Joanna, Kosaki, Kenjiro, Okano, Hideyuki
Published in eLife (28.11.2017)
Published in eLife (28.11.2017)
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Carvedilol suppresses ryanodine receptor-dependent Ca2+ bursts in human neurons bearing PSEN1 variants found in early onset Alzheimer's disease
Hori, Atsushi, Inaba, Haruka, Hato, Takashi, Tanaka, Kimie, Sato, Shoichi, Okamoto, Mizuho, Horiuchi, Yuna, Paran, Faith Jessica, Tabe, Yoko, Mori, Shusuke, Rosales, Corina, Akamatsu, Wado, Murayama, Takashi, Kurebayashi, Nagomi, Sakurai, Takashi, Ai, Tomohiko, Miida, Takashi
Published in PloS one (2024)
Published in PloS one (2024)
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Systemic Metabolic Alteration Dependent on the Thyroid‐Liver Axis in Early PD
Miyamoto, Kengo, Saiki, Shinji, Matsumoto, Hirotaka, Suzuki, Ayami, Yamashita, Yuri, Iseki, Tatou, Ueno, Shin‐Ichi, Shiina, Kenta, Kataura, Tetsushi, Kamagata, Koji, Imamichi, Yoko, Sasazawa, Yukiko, Fujimaki, Motoki, Akamatsu, Wado, Hattori, Nobutaka
Published in Annals of neurology (01.02.2023)
Published in Annals of neurology (01.02.2023)
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In vitro monitoring of HTR2A-positive neurons derived from human-induced pluripotent stem cells
Nakai, Kento, Shiga, Takahiro, Yasuhara, Rika, Sarkar, Avijite Kumer, Abe, Yuka, Nakamura, Shiro, Hoashi, Yurie, Kotani, Keisuke, Tatsumoto, Shoji, Ishikawa, Hiroe, Go, Yasuhiro, Inoue, Tomio, Mishima, Kenji, Akamatsu, Wado, Baba, Kazuyoshi
Published in Scientific reports (29.07.2021)
Published in Scientific reports (29.07.2021)
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