Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction
Qi, Weier, Keenan, Hillary A, Li, Qian, Ishikado, Atsushi, Kannt, Aimo, Sadowski, Thorsten, Yorek, Mark A, Wu, I-Hsien, Lockhart, Samuel, Coppey, Lawrence J, Pfenninger, Anja, Liew, Chong Wee, Qiang, Guifen, Burkart, Alison M, Hastings, Stephanie, Pober, David, Cahill, Christopher, Niewczas, Monika A, Israelsen, William J, Tinsley, Liane, Stillman, Isaac E, Amenta, Peter S, Feener, Edward P, Vander Heiden, Matthew G, Stanton, Robert C, King, George L
Published in Nature medicine (01.06.2017)
Published in Nature medicine (01.06.2017)
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Journal Article
The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2
Krasemann, Susanne, Haferkamp, Undine, Pfefferle, Susanne, Woo, Marcel S., Heinrich, Fabian, Schweizer, Michaela, Appelt-Menzel, Antje, Cubukova, Alevtina, Barenberg, Janica, Leu, Jennifer, Hartmann, Kristin, Thies, Edda, Littau, Jessica Lisa, Sepulveda-Falla, Diego, Zhang, Liang, Ton, Kathy, Liang, Yan, Matschke, Jakob, Ricklefs, Franz, Sauvigny, Thomas, Sperhake, Jan, Fitzek, Antonia, Gerhartl, Anna, Brachner, Andreas, Geiger, Nina, König, Eva-Maria, Bodem, Jochen, Franzenburg, Sören, Franke, Andre, Moese, Stefan, Müller, Franz-Josef, Geisslinger, Gerd, Claussen, Carsten, Kannt, Aimo, Zaliani, Andrea, Gribbon, Philip, Ondruschka, Benjamin, Neuhaus, Winfried, Friese, Manuel A., Glatzel, Markus, Pless, Ole
Published in Stem cell reports (08.02.2022)
Published in Stem cell reports (08.02.2022)
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Journal Article
Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy
Gordin, Daniel, Shah, Hetal, Shinjo, Takanori, St-Louis, Ronald, Qi, Weier, Park, Kyoungmin, Paniagua, Samantha M, Pober, David M, Wu, I-Hsien, Bahnam, Vanessa, Brissett, Megan J, Tinsley, Liane J, Dreyfuss, Jonathan M, Pan, Hui, Dong, Yutong, Niewczas, Monika A, Amenta, Peter, Sadowski, Thorsten, Kannt, Aimo, Keenan, Hillary A, King, George L
Published in Diabetes care (01.07.2019)
Published in Diabetes care (01.07.2019)
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Journal Article
Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia
Fielding, Roger A, Vellas, Bruno, Evans, William J, Bhasin, Shalender, Morley, John E, Newman, Anne B, Abellan van Kan, Gabor, Andrieu, Sandrine, Bauer, Juergen, Breuille, Denis, Cederholm, Tommy, Chandler, Julie, De Meynard, Capucine, Donini, Lorenzo, Harris, Tamara, Kannt, Aimo, Keime Guibert, Florence, Onder, Graziano, Papanicolaou, Dimitris, Rolland, Yves, Rooks, Daniel, Sieber, Cornel, Souhami, Elisabeth, Verlaan, Sjors, Zamboni, Mauro
Published in Journal of the American Medical Directors Association (2011)
Published in Journal of the American Medical Directors Association (2011)
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Journal Article
Novel Inhibitors of Nicotinamide- N -Methyltransferase for the Treatment of Metabolic Disorders
Kannt, Aimo, Rajagopal, Sridharan, Hallur, Mahanandeesha S, Swamy, Indu, Kristam, Rajendra, Dhakshinamoorthy, Saravanakumar, Czech, Joerg, Zech, Gernot, Schreuder, Herman, Ruf, Sven
Published in Molecules (Basel, Switzerland) (13.02.2021)
Published in Molecules (Basel, Switzerland) (13.02.2021)
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Journal Article
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
Kannt, Aimo, Rajagopal, Sridharan, Kadnur, Sanjay Venkatachalapathi, Suresh, Juluri, Bhamidipati, Ravi Kanth, Swaminathan, Srinivasan, Hallur, Mahanandeesha Siddappa, Kristam, Rajendra, Elvert, Ralf, Czech, Jörg, Pfenninger, Anja, Rudolph, Christine, Schreuder, Herman, Chandrasekar, Devaraj Venkatapura, Mane, Vishal Subhash, Birudukota, Swarnakumari, Shaik, Shama, Zope, Bharat Ravindra, Burri, Raghunadha Reddy, Anand, Niranjan Naranapura, Thakur, Manish Kumar, Singh, Manvi, Parveen, Reejuana, Kandan, Saravanan, Mullangi, Ramesh, Yura, Takeshi, Gosu, Ramachandraiah, Ruf, Sven, Dhakshinamoorthy, Saravanakumar
Published in Scientific reports (26.02.2018)
Published in Scientific reports (26.02.2018)
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Journal Article
Effects of Whole-Body Adenylyl Cyclase 5 ( Adcy5 ) Deficiency on Systemic Insulin Sensitivity and Adipose Tissue
Dommel, Sebastian, Hoffmann, Anne, Berger, Claudia, Kern, Matthias, Klöting, Nora, Kannt, Aimo, Blüher, Matthias
Published in International journal of molecular sciences (21.04.2021)
Published in International journal of molecular sciences (21.04.2021)
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Journal Article
Ibuprofen, Flurbiprofen, Etoricoxib or Paracetamol Do Not Influence ACE2 Expression and Activity In Vitro or in Mice and Do Not Exacerbate In-Vitro SARS-CoV-2 Infection
de Bruin, Natasja, Schneider, Ann-Kathrin, Reus, Philipp, Talmon, Sonja, Ciesek, Sandra, Bojkova, Denisa, Cinatl, Jindrich, Lodhi, Imran, Charlesworth, Bruce, Sinclair, Simon, Pennick, Graham, Laughey, William F, Gribbon, Philip, Kannt, Aimo, Schiffmann, Susanne
Published in International journal of molecular sciences (19.01.2022)
Published in International journal of molecular sciences (19.01.2022)
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Journal Article
Association Between Serum Carnosinase Concentration and Activity and Renal Function Impairment in a Type-2 Diabetes Cohort
Qiu, Jiedong, Yard, Benito A., Krämer, Bernhard K., van Goor, Harry, van Dijk, Peter, Kannt, Aimo
Published in Frontiers in pharmacology (08.07.2022)
Published in Frontiers in pharmacology (08.07.2022)
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Journal Article
Running on mixed fuel‐dual agonistic approach of GLP‐1 and GCG receptors leads to beneficial impact on body weight and blood glucose control: A comparative study between mice and non‐human primates
Elvert, Ralf, Herling, Andreas W., Bossart, Martin, Weiss, Tilo, Zhang, Baohong, Wenski, Pierre, Wandschneider, Jörn, Kleutsch, Sabrina, Butty, Uwe, Kannt, Aimo, Wagner, Michael, Haack, Torsten, Evers, Andreas, Dudda, Angela, Lorenz, Martin, Keil, Stefanie, Larsen, Philip J.
Published in Diabetes, obesity & metabolism (01.08.2018)
Published in Diabetes, obesity & metabolism (01.08.2018)
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Journal Article
Novel tricyclic small molecule inhibitors of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
Ruf, Sven, Rajagopal, Sridharan, Kadnur, Sanjay Venkatachalapathi, Hallur, Mahanandeesha S., Rani, Shilpa, Kristam, Rajendra, Swaminathan, Srinivasan, Zope, Bharat Ravindra, Gondrala, Pavan Kumar, Swamy, Indu, Putta, V. P. Rama Kishore, Kandan, Saravanan, Zech, Gernot, Schreuder, Herman, Rudolph, Christine, Elvert, Ralf, Czech, Joerg, Birudukota, Swarnakumari, Siddiqui, M. Amir, Anand, Niranjan Naranapura, Mane, Vishal Subhash, Dittakavi, Sreekanth, Suresh, Juluri, Gosu, Ramachandraiah, Ramesh, Mullangi, Yura, Takeshi, Dhakshinamoorthy, Saravanakumar, Kannt, Aimo
Published in Scientific reports (14.09.2022)
Published in Scientific reports (14.09.2022)
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Journal Article
Team Players or Opponents: Coadministration of Selective Glucagon and GLP-1 Receptor Agonists in Obese Diabetic Monkeys
Elvert, Ralf, Bossart, Martin, Herling, Andreas W, Weiss, Tilo, Zhang, Baohong, Kannt, Aimo, Wagner, Michael, Haack, Torsten, Evers, Andreas, Dudda, Angela, Keil, Stefanie, Lorenz, Martin, Lorenz, Katrin, Riz, Michela, Hennerici, Wolfgang, Larsen, Philip J
Published in Endocrinology (Philadelphia) (01.08.2018)
Published in Endocrinology (Philadelphia) (01.08.2018)
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Journal Article
Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase
Ruf, Sven, Hallur, Mahanandeesha Siddappa, Anchan, Nisha K., Swamy, Indu N., Murugesan, Karthikai Raj, Sarkar, Sayantani, Narasimhulu, Lokesh Kananti, Putta, V.P. Rama Kishore, Shaik, Shama, Chandrasekar, Devaraj Venkatapura, Mane, Vishal Subhash, Kadnur, Sanjay Venkatachalapathi, Suresh, Juluri, Bhamidipati, Ravi Kanth, Singh, Manvi, Burri, Raghunadha Reddy, Kristam, Rajendra, Schreuder, Herman, Czech, Joerg, Rudolph, Christine, Marker, Alexander, Langer, Thomas, Mullangi, Ramesh, Yura, Takeshi, Gosu, Ramachandraiah, Kannt, Aimo, Dhakshinamoorthy, Saravanakumar, Rajagopal, Sridharan
Published in Bioorganic & medicinal chemistry letters (01.03.2018)
Published in Bioorganic & medicinal chemistry letters (01.03.2018)
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Journal Article
Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy
da Silva, Priscila, Mora, Javier, You, Xin, Wiechmann, Svenja, Putyrski, Mateusz, Garcia-Pardo, Javier, Kannt, Aimo, Ernst, Andreas, Bruene, Bernhard, Weigert, Andreas
Published in Journal for immunotherapy of cancer (28.08.2024)
Published in Journal for immunotherapy of cancer (28.08.2024)
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Journal Article
Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD
Kanoni, Stavroula, Kumar, Satish, Amerikanou, Charalampia, Kurth, Mary Jo, Stathopoulou, Maria G., Bourgeois, Stephane, Masson, Christine, Kannt, Aimo, Cesarini, Lucia, Kontoe, Maria-Spyridoula, Milanović, Maja, Roig, Francisco J., Beribaka, Mirjana, Campolo, Jonica, Jiménez-Hernández, Nuria, Milošević, Nataša, Llorens, Carlos, Smyrnioudis, Ilias, Francino, M. Pilar, Milić, Nataša, Kaliora, Andriana C., Trivella, Maria Giovanna, Ruddock, Mark W., Medić-Stojanoska, Milica, Gastaldelli, Amalia, Lamont, John, Deloukas, Panos, Dedoussis, George V., Visvikis-Siest, Sophie
Published in Frontiers in immunology (07.05.2021)
Published in Frontiers in immunology (07.05.2021)
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Journal Article
Analysis of 16 studies in nine rodent models does not support the hypothesis that diabetic polyuria is a main reason of urinary bladder enlargement
Yesilyurt, Zeynep E., Matthes, Jan, Hintermann, Edith, Castañeda, Tamara R., Elvert, Ralf, Beltran-Ornelas, Jesus H., Silva-Velasco, Diana L., Xia, Ning, Kannt, Aimo, Christen, Urs, Centurión, David, Li, Huige, Pautz, Andrea, Arioglu-Inan, Ebru, Michel, Martin C.
Published in Frontiers in physiology (08.08.2022)
Published in Frontiers in physiology (08.08.2022)
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Journal Article
A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice
Wang, Xiaobo, Sommerfeld, Mark R., Jahn‐Hofmann, Kerstin, Cai, Bishuang, Filliol, Aveline, Remotti, Helen E., Schwabe, Robert F., Kannt, Aimo, Tabas, Ira
Published in Hepatology communications (01.09.2019)
Published in Hepatology communications (01.09.2019)
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Journal Article
Systemic treatment with erythropoietin protects the neurovascular unit in a rat model of retinal neurodegeneration
Busch, Stephanie, Kannt, Aimo, Kolibabka, Matthias, Schlotterer, Andreas, Wang, Qian, Lin, Jihong, Feng, Yuxi, Hoffmann, Sigrid, Gretz, Norbert, Hammes, Hans-Peter
Published in PloS one (11.07.2014)
Published in PloS one (11.07.2014)
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