A high-efficiency system for the generation and study of human induced pluripotent stem cells
Maherali, Nimet, Ahfeldt, Tim, Rigamonti, Alessandra, Utikal, Jochen, Cowan, Chad, Hochedlinger, Konrad
Published in Cell stem cell (11.09.2008)
Published in Cell stem cell (11.09.2008)
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Journal Article
Generation of Multipotent Lung and Airway Progenitors from Mouse ESCs and Patient-Specific Cystic Fibrosis iPSCs
Mou, Hongmei, Zhao, Rui, Sherwood, Richard, Ahfeldt, Tim, Lapey, Allen, Wain, John, Sicilian, Leonard, Izvolsky, Konstantin, Lau, Frank H., Musunuru, Kiran, Cowan, Chad, Rajagopal, Jayaraj
Published in Cell stem cell (06.04.2012)
Published in Cell stem cell (06.04.2012)
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Journal Article
Disease-Specific Induced Pluripotent Stem Cells
Park, In-Hyun, Arora, Natasha, Huo, Hongguang, Maherali, Nimet, Ahfeldt, Tim, Shimamura, Akiko, Lensch, M. William, Cowan, Chad, Hochedlinger, Konrad, Daley, George Q.
Published in Cell (05.09.2008)
Published in Cell (05.09.2008)
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Journal Article
A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides
Paul, Kimberly C., Krolewski, Richard C., Lucumi Moreno, Edinson, Blank, Jack, Holton, Kristina M., Ahfeldt, Tim, Furlong, Melissa, Yu, Yu, Cockburn, Myles, Thompson, Laura K., Kreymerman, Alexander, Ricci-Blair, Elisabeth M., Li, Yu Jun, Patel, Heer B., Lee, Richard T., Bronstein, Jeff, Rubin, Lee L., Khurana, Vikram, Ritz, Beate
Published in Nature communications (16.05.2023)
Published in Nature communications (16.05.2023)
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Journal Article
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model
Morrone Parfitt, Gustavo, Coccia, Elena, Goldman, Camille, Whitney, Kristen, Reyes, Ricardo, Sarrafha, Lily, Nam, Ki Hong, Sohail, Soha, Jones, Drew R., Crary, John F., Ordureau, Alban, Blanchard, Joel, Ahfeldt, Tim
Published in Nature communications (10.01.2024)
Published in Nature communications (10.01.2024)
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Journal Article
Publisher Correction: A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides
Paul, Kimberly C., Krolewski, Richard C., Lucumi Moreno, Edinson, Blank, Jack, Holton, Kristina M., Ahfeldt, Tim, Furlong, Melissa, Yu, Yu, Cockburn, Myles, Thompson, Laura K., Kreymerman, Alexander, Ricci-Blair, Elisabeth M., Li, Yu Jun, Patel, Heer B., Lee, Richard T., Bronstein, Jeff, Rubin, Lee L., Khurana, Vikram, Ritz, Beate
Published in Nature communications (23.06.2023)
Published in Nature communications (23.06.2023)
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Journal Article
Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons
Ahfeldt, Tim, Ordureau, Alban, Bell, Christina, Sarrafha, Lily, Sun, Chicheng, Piccinotti, Silvia, Grass, Tobias, Parfitt, Gustavo M., Paulo, Joao A., Yanagawa, Fumiki, Uozumi, Takayuki, Kiyota, Yasujiro, Harper, J. Wade, Rubin, Lee L.
Published in Stem cell reports (14.01.2020)
Published in Stem cell reports (14.01.2020)
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Journal Article
Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity
Sarrafha, Lily, Neavin, Drew R., Parfitt, Gustavo M., Kruglikov, Ilya A., Whitney, Kristen, Reyes, Ricardo, Coccia, Elena, Kareva, Tatyana, Goldman, Camille, Tipon, Regine, Croft, Gist, Crary, John F., Powell, Joseph E., Blanchard, Joel, Ahfeldt, Tim
Published in iScience (15.09.2023)
Published in iScience (15.09.2023)
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Journal Article
Efficient culturing and genetic manipulation of human pluripotent stem cells
Schinzel, Robert T, Ahfeldt, Tim, Lau, Frank H, Lee, Youn-Kyoung, Cowley, Alicia, Shen, Tony, Peters, Derek, Lum, David H, Cowan, Chad A
Published in PloS one (15.12.2011)
Published in PloS one (15.12.2011)
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Journal Article
Pattern specification and immune response transcriptional signatures of pericardial and subcutaneous adipose tissue
Lau, Frank H, Deo, Rahul C, Mowrer, Gregory, Caplin, Joshua, Ahfeldt, Tim, Kaplan, Adam, Ptaszek, Leon, Walker, Jennifer D, Rosengard, Bruce R, Cowan, Chad A
Published in PloS one (11.10.2011)
Published in PloS one (11.10.2011)
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Journal Article
Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy
Ordureau, Alban, Kraus, Felix, Zhang, Jiuchun, An, Heeseon, Park, Sookhee, Ahfeldt, Tim, Paulo, Joao A., Harper, J. Wade
Published in Molecular cell (16.12.2021)
Published in Molecular cell (16.12.2021)
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Journal Article
Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells
Foudi, Adlen, Stadtfeld, Matthias, Hochedlinger, Konrad, Maherali, Nimet, Hock, Hanno, Ahfeldt, Tim, Eminli, Sarah, Mostoslavsky, Gustavo
Published in Nature genetics (01.09.2009)
Published in Nature genetics (01.09.2009)
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Journal Article
Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
Ordureau, Alban, Paulo, Joao A., Zhang, Wei, Ahfeldt, Tim, Zhang, Jiuchun, Cohn, Erin F., Hou, Zhonggang, Heo, Jin-Mi, Rubin, Lee L., Sidhu, Sachdev S., Gygi, Steven P., Harper, J. Wade
Published in Molecular cell (19.04.2018)
Published in Molecular cell (19.04.2018)
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Journal Article
Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
Warren, Luigi, Manos, Philip D., Ahfeldt, Tim, Loh, Yuin-Han, Li, Hu, Lau, Frank, Ebina, Wataru, Mandal, Pankaj K., Smith, Zachary D., Meissner, Alexander, Daley, George Q., Brack, Andrew S., Collins, James J., Cowan, Chad, Schlaeger, Thorsten M., Rossi, Derrick J.
Published in Cell stem cell (05.11.2010)
Published in Cell stem cell (05.11.2010)
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Journal Article
Investigation into the pathophysiology of GBA1-associated Parkinson's disease using organelle-specific proteomics
Chen, Chase, Chen, Yu, Sam, Richard, Vrijsen, Stephanie, Coccia, Elena, Vangheluwe, Peter, Ahfeldt, Tim, Sidransky, Ellen
Published in Molecular genetics and metabolism (01.02.2022)
Published in Molecular genetics and metabolism (01.02.2022)
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Journal Article
Investigation into the pathophysiology of -associated Parkinson's disease using organelle-specific proteomics
Chen, Chase, Chen, Yu, Sam, Richard, Vrijsen, Stephanie, Coccia, Elena, Vangheluwe, Peter, Ahfeldt, Tim, Sidransky, Ellen
Published in Molecular genetics and metabolism (01.02.2022)
Published in Molecular genetics and metabolism (01.02.2022)
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Journal Article
A TALEN Genome-Editing System for Generating Human Stem Cell-Based Disease Models
Ding, Qiurong, Lee, Youn-Kyoung, Schaefer, Esperance A.K., Peters, Derek T., Veres, Adrian, Kim, Kevin, Kuperwasser, Nicolas, Motola, Daniel L., Meissner, Torsten B., Hendriks, William T., Trevisan, Marta, Gupta, Rajat M., Moisan, Annie, Banks, Eric, Friesen, Max, Schinzel, Robert T., Xia, Fang, Tang, Alexander, Xia, Yulei, Figueroa, Emmanuel, Wann, Amy, Ahfeldt, Tim, Daheron, Laurence, Zhang, Feng, Rubin, Lee L., Peng, Lee F., Chung, Raymond T., Musunuru, Kiran, Cowan, Chad A.
Published in Cell stem cell (07.02.2013)
Published in Cell stem cell (07.02.2013)
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