Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I-DNA complexes
Regairaz, Marie, Zhang, Yong-Wei, Fu, Haiqing, Agama, Keli K, Tata, Nalini, Agrawal, Surbhi, Aladjem, Mirit I, Pommier, Yves
Published in The Journal of cell biology (28.11.2011)
Published in The Journal of cell biology (28.11.2011)
Get full text
Journal Article
Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells
Zhang, Yong-Wei, Regairaz, Marie, Seiler, Jennifer A, Agama, Keli K, Doroshow, James H, Pommier, Yves
Published in Nucleic acids research (01.05.2011)
Published in Nucleic acids research (01.05.2011)
Get full text
Journal Article
2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights
Elbadawi, Mostafa M., Eldehna, Wagdy M., Abd El-Hafeez, Amer Ali, Somaa, Warda R., Albohy, Amgad, Al-Rashood, Sara T., Agama, Keli K., Elkaeed, Eslam B., Ghosh, Pradipta, Pommier, Yves, Abe, Manabu
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Get full text
Journal Article
Novel Indenoisoquinolines NSC 725776 and NSC 724998 Produce Persistent Topoisomerase I Cleavage Complexes and Overcome Multidrug Resistance
ANTONY, Smitha, AGAMA, Keli K, POMMIER, Yves, MIAO, Ze-Hong, TAKAGI, Kazutaka, WRIGHT, Mollie H, ROBLES, Ana I, VARTICOVSKI, Lyuba, NAGARAJAN, Muthukaman, MORRELL, Andrew, CUSHMAN, Mark
Published in Cancer research (Chicago, Ill.) (01.11.2007)
Published in Cancer research (Chicago, Ill.) (01.11.2007)
Get full text
Journal Article
Targeting tumor cells expressing p53 with a water-soluble inhibitor of Hdm2
Kitagaki, Jirouta, Agama, Keli K, Pommier, Yves, Yang, Yili, Weissman, Allan M
Published in Molecular cancer therapeutics (01.08.2008)
Published in Molecular cancer therapeutics (01.08.2008)
Get full text
Journal Article
Discovery of 4-alkoxy-2-aryl-6,7-dimethoxyquinolines as a new class of topoisomerase I inhibitors endowed with potent in vitro anticancer activity
Elbadawi, Mostafa M., Eldehna, Wagdy M., Wang, Wenjie, Agama, Keli K., Pommier, Yves, Abe, Manabu
Published in European journal of medicinal chemistry (05.04.2021)
Published in European journal of medicinal chemistry (05.04.2021)
Get full text
Journal Article
Bisindenoisoquinoline Bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA Intercalator and Topoisomerase Inhibitor with Antitumor Activity
Antony, Smitha, Agama, Keli K, Miao, Ze-Hong, Hollingshead, Melinda, Holbeck, Susan L, Wright, Mollie H, Varticovski, Lyuba, Nagarajan, Muthukaman, Morrell, Andrew, Cushman, Mark, Pommier, Yves
Published in Molecular pharmacology (01.09.2006)
Published in Molecular pharmacology (01.09.2006)
Get full text
Journal Article
TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor
Jo, Ukhyun, Murai, Yasuhisa, Agama, Keli K, Sun, Yilun, Saha, Liton Kumar, Yang, Xi, Arakawa, Yasuhiro, Gayle, Sophia, Jones, Kelli, Paralkar, Vishwas, Sundaram, Ranjini K, Van Doorn, Jinny, Vasquez, Juan C, Bindra, Ranjit S, Choi, Woo Suk, Pommier, Yves
Published in Molecular cancer therapeutics (05.07.2022)
Published in Molecular cancer therapeutics (05.07.2022)
Get full text
Journal Article
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1
Antony, Smitha, Marchand, Christophe, Stephen, Andrew G, Thibaut, Laurent, Agama, Keli K, Fisher, Robert J, Pommier, Yves
Published in Nucleic acids research (01.07.2007)
Published in Nucleic acids research (01.07.2007)
Get full text
Journal Article
The Iron Chelator Dp44mT Causes DNA Damage and Selective Inhibition of Topoisomerase IIα in Breast Cancer Cells
Rao, V. Ashutosh, Klein, Sarah R., Agama, Keli K., Toyoda, Eriko, Adachi, Noritaka, Pommier, Yves, Shacter, Emily B.
Published in Cancer research (Chicago, Ill.) (01.02.2009)
Published in Cancer research (Chicago, Ill.) (01.02.2009)
Get full text
Journal Article
The Iron Chelator Dp44mT Causes DNA Damage and Selective Inhibition of Topoisomerase Ilα in Breast Cancer Cells
ASHUTOSH RAO, V, KLEIN, Sarah R, AGAMA, Keli K, TOYODA, Eriko, ADACHI, Noritaka, POMMIER, Yves, SHACTER, Emily B
Published in Cancer research (Chicago, Ill.) (2009)
Get full text
Published in Cancer research (Chicago, Ill.) (2009)
Journal Article
The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells
Rao, V Ashutosh, Klein, Sarah R, Agama, Keli K, Toyoda, Eriko, Adachi, Noritaka, Pommier, Yves, Shacter, Emily B
Published in Cancer research (Chicago, Ill.) (01.02.2009)
Published in Cancer research (Chicago, Ill.) (01.02.2009)
Get full text
Journal Article
N-Substituted indenoisoquinolines and syntheses thereof
CUSHMAN, MARK S, MORRELL, ANDREW E, ANTONY, SMITHA, AGAMA, KELI K, NAGARAJAN, MUTHUKAMAN, POMMIER, YVES G
Year of Publication 02.06.2016
Get full text
Year of Publication 02.06.2016
Patent
N-Substituted indenoisoquinolines and syntheses thereof
CUSHMAN, MARK S, MORRELL, ANDREW E, ANTONY, SMITHA, AGAMA, KELI K, NAGARAJAN, MUTHUKAMAN, POMMIER, YVES G
Year of Publication 25.02.2016
Get full text
Year of Publication 25.02.2016
Patent
N-substituted indenoisoquinolines and syntheses thereof
BECK DANIEL E, AGAMA KELI K, ANTONY SMITHA, POMMIER YVES GEORGE, CUSHMAN MARK S, MORRELL ANDREW E, NAGARAJAN MUTHUKAMAN
Year of Publication 12.07.2016
Get full text
Year of Publication 12.07.2016
Patent
N-substituted indenoisoquinolines and syntheses thereof
BECK DANIEL E, AGAMA KELI K, POMMIER YVES G, ANTONY SMITHA, CUSHMAN MARK S, MORRELL ANDREW E, NAGARAJAN MUTHUKAMAN
Year of Publication 22.12.2015
Get full text
Year of Publication 22.12.2015
Patent
N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF
AGAMA KELI K, POMMIER YVES G, ANTONY SMITHA, CUSHMAN MARK S, MORRELL ANDREW E, NAGARAJAN MUTHUKAMAN
Year of Publication 13.11.2014
Get full text
Year of Publication 13.11.2014
Patent
N-substituted indenoisoquinolines and syntheses thereof
AGAMA KELI K, POMMIER YVES G, ANTONY SMITHA, CUSHMAN MARK S, MORRELL ANDREW E, NAGARAJAN MUTHUKAMAN
Year of Publication 09.09.2014
Get full text
Year of Publication 09.09.2014
Patent
N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF
CUSHMAN, MARK S, MORRELL, ANDREW E, ANTONY, SMITHA, AGAMA, KELI K, NAGARAJAN, MUTHUKAMAN, POMMIER, YVES G
Year of Publication 08.07.2014
Get full text
Year of Publication 08.07.2014
Patent
N-SUBSTITUTED INDENOISOQUINOLINES AND SYNTHESES THEREOF
BECK DANIEL E, AGAMA KELI K, ANTONY SMITHA, POMMIER YVES GEORGE, CUSHMAN MARK S, MORRELL ANDREW E, NAGARAJAN MUTHUKAMAN
Year of Publication 06.08.2015
Get full text
Year of Publication 06.08.2015
Patent