Unravelling triple-negative breast cancer molecular heterogeneity using an integrative multiomic analysis
Bareche, Y., Venet, D., Ignatiadis, M., Aftimos, P., Piccart, M., Rothe, F., Sotiriou, C.
Published in Annals of oncology (01.04.2018)
Published in Annals of oncology (01.04.2018)
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Molecular imaging as a tool to investigate heterogeneity of advanced HER2-positive breast cancer and to predict patient outcome under trastuzumab emtansine (T-DM1): the ZEPHIR trial
Gebhart, G., Lamberts, L.E., Wimana, Z., Garcia, C., Emonts, P., Ameye, L., Stroobants, S., Huizing, M., Aftimos, P., Tol, J., Oyen, W.J.G., Vugts, D.J., Hoekstra, O.S., Schröder, C.P., Menke-van der Houven van Oordt, C.W., Guiot, T., Brouwers, A.H., Awada, A., de Vries, E.G.E., Flamen, P.
Published in Annals of oncology (01.04.2016)
Published in Annals of oncology (01.04.2016)
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Biomarker analyses in the phase III ASCENT study of sacituzumab govitecan versus chemotherapy in patients with metastatic triple-negative breast cancer
Bardia, A., Tolaney, S.M., Punie, K., Loirat, D., Oliveira, M., Kalinsky, K., Zelnak, A., Aftimos, P., Dalenc, F., Sardesai, S., Hamilton, E., Sharma, P., Recalde, S., Gil, E.C., Traina, T., O’Shaughnessy, J., Cortes, J., Tsai, M., Vahdat, L., Diéras, V., Carey, L.A., Rugo, H.S., Goldenberg, D.M., Hong, Q., Olivo, M., Itri, L.M., Hurvitz, S.A.
Published in Annals of oncology (01.09.2021)
Published in Annals of oncology (01.09.2021)
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The AURORA initiative for metastatic breast cancer
Zardavas, D, Maetens, M, Irrthum, A, Goulioti, T, Engelen, K, Fumagalli, D, Salgado, R, Aftimos, P, Saini, K S, Sotiriou, C, Campbell, P, Dinh, P, von Minckwitz, G, Gelber, R D, Dowsett, M, Di Leo, A, Cameron, D, Baselga, J, Gnant, M, Goldhirsch, A, Norton, L, Piccart, M
Published in British journal of cancer (11.11.2014)
Published in British journal of cancer (11.11.2014)
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Efficacy of olaparib in advanced cancers with germline or somatic mutations in BRCA1, BRCA2, CHEK2 and ATM, a Belgian Precision tumor-agnostic phase II study
Joris, S., Denys, H., Collignon, J., Rasschaert, M., T’Kint de Roodenbeke, D., Duhoux, F.P., Canon, J.-L., Tejpar, S., Mebis, J., Decoster, L., Aftimos, P., De Grève, J.
Published in ESMO open (01.12.2023)
Published in ESMO open (01.12.2023)
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First-in-human, first-in-class study of the CD44v6 inhibitor AMC303 as monotherapy in patients with advanced epithelial tumors
Calvo, E, Aftimos, P G, Azaro, A, de Miguel, M J, Jungels, C, Zeron-Medina Cuairan, J, Nuciforo, P G, Ehmer, P, Martin, A, Bender, H K, Dembowsky, K
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Safety, clinical activity and pharmacological biomarker evaluation of the DNA-dependent protein kinase (DNA-PK) inhibitor M3814: Results from two phase I trials
Mau-Sorensen, M., van Bussel, M., Kuipers, M., Nielsen, D.L., Verheul, H.M., Aftimos, P., de Jonge, M.J.A., van Triest, B., Falkenius, J., Debus, J., Troost, E., Samuels, M., Sarholz, B., Budach, V., Goel, S., Locatelli, G., Geertsen, P.F.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Antitumor activity of lurbinectedin in combination with oral capecitabine in patients with metastatic breast cancer
Awada, A.H., Boni, V., Moreno, V., Aftimos, P., Kahatt, C., Luepke-Estefan, X.E., Siguero, M., Fernandez-Teruel, C., Cullell-Young, M., Tabernero, J.
Published in ESMO open (01.12.2022)
Published in ESMO open (01.12.2022)
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Lucitanib for the treatment of HR+ HER2- metastatic breast cancer (MBC) patients (pts): Results from the multicohort phase II FINESSE trial
Hui, R., Pearson, A., Cortes Castan, J., Campbell, C., Poirot, C., Azim, H.A., Fumagalli, D., Lambertini, M., Daly, F., Arahmani, A., Perez-Garcia, J., Aftimos, P.G., Bedard, P., Xuereb, L., Loibl, S., Loi, S., Pierrat, M.-J., Turner, N.C., André, F., Curigliano, G.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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A first-in-class, first-in-human phase I/IIa trial of CAN04, targeting interleukin-1 receptor accessory protein (IL1RAP), in patients with solid tumors
Awada, A., Eskens, F.A.L.M., Robbrecht, D.G., Lassen, U.N., Sorensen, M., Schellens, J.H.M., de Groot, J.S., Jungels, C., Aftimos, P.G., Fretland, S.O., Thorsson, L., Guren, T.K.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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Clinical utility of complex multi-platform profiling in metastatic cancer patients
Garcia Foncillas, J., Aftimos, P.G., Barthelemy, P., Bellmunt, J., Berchem, G., Camps, C., de las Peñas, R., Finzel, A., Hervonen, J.P., Joensuu, T., Kong, A., Mackay, J., Mikropoulos, C., Mokbel, K., Mouysset, J.-L., Perren, T.-J., Guitti, G., Laes, J.-F.
Published in Annals of oncology (01.10.2018)
Published in Annals of oncology (01.10.2018)
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108 CD70 (TNFSF7), a receptor involved in acute immune modulation of viral infection, is frequently overexpressed in solid and hematological malignancies
Jacobs, J, Zwaenepoel, K, Aftimos, P, Rolfo, C, Rottey, S, de Lendonck, L. Ysebrant, Silence, K, Awada, A, Thibault, A, Pauwels, P
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
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528 Intratumoural treatment with LTX-, an oncolytic peptide immunotherapy, in patients with advanced metastatic disease induces CD8 effector cells and regression in some injected tumours
Spicer, J, Awada, A, Brunsvig, P, Saunders, A, Olsen, W.M, Nicolaisen, B, Rekdal, O, Laruelle, M, Marjuadi, F, Vakili, J, Aftimos, P, Barthelemy, P, Deva, S, Baurain, J.F
Published in European journal of cancer (1990) (01.09.2015)
Published in European journal of cancer (1990) (01.09.2015)
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PRECISION: the Belgian molecular profiling program of metastatic cancer for clinical decision and treatment assignment
Thouvenin, J., Van Marcke, C., Decoster, L., Raicevic, G., Punie, K., Vandenbulcke, M., Salgado, R., Van Valckenborgh, E., Maes, B., Joris, S., Steichel, D. Vander, Vranken, K., Jacobs, S., Dedeurwaerdere, F., Martens, G., Devos, H., Duhoux, F.P., Rasschaert, M., Pauwels, P., Geboes, K., Collignon, J., Tejpar, S., Canon, J.-L., Peeters, M., Rutten, A., Van de Mooter, T., Vermeij, J., Schrijvers, D., Demey, W., Lybaert, W., Van Huysse, J., Mebis, J., Awada, A., Claes, K.B.M., Hebrant, A., Van der Meulen, J., Delafontaine, B., Bempt, I. Vanden, Maetens, J., de Hemptinne, M., Rottey, S., Aftimos, P., De Grève, J.
Published in ESMO open (01.08.2022)
Published in ESMO open (01.08.2022)
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P08.03 2B3-101, GLUTATHIONE PEGYLATED LIPOSOMAL DOXORUBICIN, IN PATIENTS WITH RECURRENT HIGH GRADE GLIOMAS AND BREAST CANCER BRAIN METASTASES
Brandsma, D., Dieras, V., Altintas, S., Anders, C., Arnedos, M., Gelderblom, H., Soetekouw, P., Jager, A., van Linde, M., Aftimos, P.
Published in Neuro-oncology (Charlottesville, Va.) (01.09.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.09.2014)
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