Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation
Afroz, Tariq, Hock, Eva-Maria, Ernst, Patrick, Foglieni, Chiara, Jambeau, Melanie, Gilhespy, Larissa A. B., Laferriere, Florent, Maniecka, Zuzanna, Plückthun, Andreas, Mittl, Peer, Paganetti, Paolo, Allain, Frédéric H. T., Polymenidou, Magdalini
Published in Nature communications (29.06.2017)
Published in Nature communications (29.06.2017)
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Journal Article
TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates
Laferrière, Florent, Maniecka, Zuzanna, Pérez-Berlanga, Manuela, Hruska-Plochan, Marian, Gilhespy, Larissa, Hock, Eva-Maria, Wagner, Ulrich, Afroz, Tariq, Boersema, Paul J., Barmettler, Gery, Foti, Sandrine C., Asi, Yasmine T., Isaacs, Adrian M., Al-Amoudi, Ashraf, Lewis, Amanda, Stahlberg, Henning, Ravits, John, De Giorgi, Francesca, Ichas, François, Bezard, Erwan, Picotti, Paola, Lashley, Tammaryn, Polymenidou, Magdalini
Published in Nature neuroscience (01.01.2019)
Published in Nature neuroscience (01.01.2019)
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Journal Article
One, Two, Three, Four! How Multiple RRMs Read the Genome Sequence
Afroz, Tariq, Cienikova, Zuzana, Cléry, Antoine, Allain, Frédéric H T
Published in Methods in enzymology (2015)
Published in Methods in enzymology (2015)
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Journal Article
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD
Afroz, Tariq, Chevalier, Elodie, Audrain, Mickael, Dumayne, Christopher, Ziehm, Tamar, Moser, Roger, Egesipe, Anne-Laure, Mottier, Lorène, Ratnam, Monisha, Neumann, Manuela, Havas, Daniel, Ollier, Romain, Piorkowska, Kasia, Chauhan, Mayank, Silva, Alberto B., Thapa, Samjhana, Stöhr, Jan, Bavdek, Andrej, Eligert, Valerie, Adolfsson, Oskar, Nelson, Peter T., Porta, Sílvia, Lee, Virginia M.-Y., Pfeifer, Andrea, Kosco-Vilbois, Marie, Seredenina, Tamara
Published in Neurobiology of disease (01.04.2023)
Published in Neurobiology of disease (01.04.2023)
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Journal Article
Split GFP technologies to structurally characterize and quantify functional biomolecular interactions of FTD-related proteins
Foglieni, Chiara, Papin, Stéphanie, Salvadè, Agnese, Afroz, Tariq, Pinton, Sandra, Pedrioli, Giona, Ulrich, Giorgio, Polymenidou, Magdalini, Paganetti, Paolo
Published in Scientific reports (25.10.2017)
Published in Scientific reports (25.10.2017)
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Journal Article
A fly trap mechanism provides sequence-specific RNA recognition by CPEB proteins
Afroz, Tariq, Skrisovska, Lenka, Belloc, Eulàlia, Guillén-Boixet, Jordina, Méndez, Raúl, Allain, Frédéric H-T
Published in Genes & development (01.07.2014)
Published in Genes & development (01.07.2014)
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Journal Article
Author Correction: Location and function of TDP-43 in platelets, alterations in neurodegenerative diseases and arising considerations for current plasma biobank protocols
Luthi-Carter, Ruth, Cappelli, Sara, Le Roux-Bourdieu, Morgan, Tentillier, Noemie, Quinn, James P., Petrozziello, Tiziana, Gopalakrishnan, Lathika, Sethi, Purva, Choudhary, Himanshi, Bartolini, Giorgia, Gebara, Elias, Stuani, Cristiana, Font, Laure, An, Jiyan, Ortega, Vanessa, Sage, Jessica, Kosa, Edina, Trombetta, Bianca A., Simeone, Roberto, Seredenina, Tamara, Afroz, Tariq, Berry, James D., Arnold, Steven E., Carlyle, Becky C., Adolfsson, Oskar, Sadri-Vakili, Ghazaleh, Buratti, Emanuele, Bowser, Robert, Agbas, Abdulbaki
Published in Scientific reports (07.11.2024)
Published in Scientific reports (07.11.2024)
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Journal Article
Location and function of TDP-43 in platelets, alterations in neurodegenerative diseases and arising considerations for current plasma biobank protocols
Luthi-Carter, Ruth, Cappelli, Sara, Le Roux-Bourdieu, Morgan, Tentillier, Noemie, Quinn, James P., Petrozziello, Tiziana, Gopalakrishnan, Lathika, Sethi, Purva, Choudhary, Himanshi, Bartolini, Giorgia, Gebara, Elias, Stuani, Cristiana, Font, Laure, An, Jiyan, Ortega, Vanessa, Sage, Jessica, Kosa, Edina, Trombetta, Bianca A., Simeone, Roberto, Seredenina, Tamara, Afroz, Tariq, Berry, James D., Arnold, Steven E., Carlyle, Becky C., Adolfsson, Oskar, Sadri-Vakili, Ghazaleh, Buratti, Emanuele, Bowser, Robert, Agbas, Abdulbaki
Published in Scientific reports (18.09.2024)
Published in Scientific reports (18.09.2024)
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Journal Article
Targeting the TDP-43 low complexity domain blocks spreading of pathology in a mouse model of ALS/FTD
Chevalier, Elodie, Audrain, Mickael, Ratnam, Monisha, Ollier, Romain, Fuchs, Aline, Piorkowska, Kasia, Pfeifer, Andrea, Kosco-Vilbois, Marie, Seredenina, Tamara, Afroz, Tariq
Published in Acta neuropathologica communications (03.10.2024)
Published in Acta neuropathologica communications (03.10.2024)
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Journal Article
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework
Ollier, Romain, Fuchs, Aline, Gauye, Florence, Piorkowska, Katarzyna, Menant, Sébastien, Ratnam, Monisha, Montanari, Paolo, Guilhot, Florence, Phillipe, Didier, Audrain, Mickael, Egesipe, Anne-Laure, Névoltris, Damien, Seredenina, Tamara, Pfeifer, Andrea, Kosco-Vilbois, Marie, Afroz, Tariq
Published in mAbs (2023)
Published in mAbs (2023)
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Journal Article
Discovery and optimization of the first‐in‐class TDP‐43 PET tracer
Seredenina, Tamara, Vokali, Efthymia, Dreyfus, Nicolas, Chevallier, Elodie, Afroz, Tariq, Jaquier, Thomas, Serra, Andreia Monica, Clavel, Mathieu, Rathnam, Monisha, Melly, Tania, Kroth, Heiko, Pfeifer, Andrea, Kosco‐Vilbois, Marie
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis
Jawaid, Ali, Woldemichael, Bisrat T., Kremer, Eloïse A., Laferriere, Florent, Gaur, Niharika, Afroz, Tariq, Polymenidou, Magdalini, Mansuy, Isabelle M.
Published in Molecular neurobiology (01.05.2019)
Published in Molecular neurobiology (01.05.2019)
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Journal Article
Memory Decline and Its Reversal in Aging and Neurodegeneration Involve miR-183/96/182 Biogenesis
Jawaid, Ali, Woldemichael, Bisrat T, Kremer, Eloïse A, Laferriere, Florent, Gaur, Niharika, Afroz, Tariq, Polymenidou, Magdalini, Mansuy, Isabelle M
Published in Molecular neurobiology (01.05.2019)
Published in Molecular neurobiology (01.05.2019)
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Journal Article
TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates
Laferrière, Florent, Maniecka, Zuzanna, Pérez-Berlanga, Manuela, Hruska-Plochan, Marian, Gilhespy, Larissa, Hock, Eva-Maria, Wagner, Ulrich, Afroz, Tariq, Boersema, Paul J, Barmettler, Gery, Foti, Sandrine C, Asi, Yasmine T, Isaacs, Adrian M, Al-Amoudi, Ashraf, Lewis, Amanda, Stahlberg, Henning, Ravits, John, de Giorgi, Francesca, Ichas, François, Bezard, Erwan, Picotti, Paola, Lashley, Tammaryn, Polymenidou, Magdalini
Published in Nature neuroscience (2019)
Published in Nature neuroscience (2019)
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Journal Article
Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF
Audrain, Mickael, Egesipe, Anne-Laure, Tentillier, Noémie, Font, Laure, Ratnam, Monisha, Mottier, Lorene, Clavel, Mathieu, Le Roux-Bourdieu, Morgan, Fenyi, Alexis, Ollier, Romain, Chevalier, Elodie, Guilhot, Florence, Fuchs, Aline, Piorkowska, Kasia, Carlyle, Becky, Arnold, Steven E, Berry, James D, Luthi-Carter, Ruth, Adolfsson, Oskar, Pfeifer, Andrea, Kosco-Vilbois, Marie, Seredenina, Tamara, Afroz, Tariq
Published in Brain communications (01.11.2023)
Published in Brain communications (01.11.2023)
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Journal Article