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Mish, Michael R., Cho, Aesop, Kirschberg, Thorsten, Xu, Jie, Sebastian Zonte, C., Fenaux, Martijn, Park, Yeojin, Babusis, Darius, Feng, Joy Y., Ray, Adrian S., Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.07.2014)
Published in Bioorganic & medicinal chemistry letters (15.07.2014)
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Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties
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Published in Bioorganic & medicinal chemistry letters (15.04.2017)
Published in Bioorganic & medicinal chemistry letters (15.04.2017)
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Mechanism of Anti-Human Immunodeficiency Virus Activity of β-d-6-Cyclopropylamino-2′,3′-Didehydro-2′,3′-Dideoxyguanosine
RAY, Adrian S, HERNANDEZ-SANTIAGO, Brenda I, CHENG, Yung-Chi, CHU, Chung K, MCCLURE, Harold, SCHINAZI, Raymond F, ANDERSON, Karen S, MATHEW, Judy S, MURAKAMI, Eisuke, BOZEMAN, Carey, XIE, Meng-Yu, DUTSCHMAN, Ginger E, GULLEN, Elizabeth, ZHENJUN YANG, HURWITZ, Selwyn
Published in Antimicrobial Agents and Chemotherapy (01.05.2005)
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Molecular assessment of the potential for renal drug interactions between tenofovir and HIV protease inhibitors
CIHLAR, Tomas, RAY, Adrian S, LAFLAMME, Genevieve, VELA, Jennifer E, TONG, Leah, FULLER, Michael D, ROY, Anupma, RHODES, Gerald R
Published in Antiviral therapy (01.01.2007)
Published in Antiviral therapy (01.01.2007)
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Synthesis and characterization of 1′-C-cyano-2′-fluoro-2′-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors
Kirschberg, Thorsten A., Mish, Michael R., Zhang, Lijun, Squires, Neil H., Wang, Ke-Yu, Cho, Aesop, Feng, Joy Y., Fenaux, Martijn, Babusis, Darius, Park, Yeojin, Ray, Adrian S., Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.03.2015)
Published in Bioorganic & medicinal chemistry letters (01.03.2015)
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Nucleotide Analogue Prodrug Tenofovir Disoproxil Enhances Lymphoid Cell Loading following Oral Administration in Monkeys
Durand-Gasselin, Lucie, Van Rompay, Koen K. A, Vela, Jennifer E, Henne, Ilana N, Lee, William A, Rhodes, Gerry R, Ray, Adrian S
Published in Molecular pharmaceutics (03.08.2009)
Published in Molecular pharmaceutics (03.08.2009)
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GS-9219/VDC-1101--a prodrug of the acyclic nucleotide PMEG has antitumor activity in spontaneous canine multiple myeloma
Thamm, Douglas H, Vail, David M, Kurzman, Ilene D, Babusis, Darius, Ray, Adrian S, Sousa-Powers, Noel, Tumas, Daniel B
Published in BMC veterinary research (25.01.2014)
Published in BMC veterinary research (25.01.2014)
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Synthesis of 1′-C-Cyano Pyrimidine Nucleosides and Characterization as HCV Polymerase Inhibitors
Kirschberg, Thorsten A., Mish, Michael, Squires, Neil H., Zonte, Sebastian, Aktoudianakis, Evangelos, Metobo, Sammy, Butler, Thomas, Ju, Xie, Cho, Aesop, Ray, Adrian S., Kim, Choung U.
Published in Nucleosides, nucleotides & nucleic acids (02.11.2015)
Published in Nucleosides, nucleotides & nucleic acids (02.11.2015)
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Evaluation of 2′-α-fluorine modified nucleoside phosphonates as potential inhibitors of HCV polymerase
Parrish, Jay P., Lee, Sharon K., Boojamra, Constantine G., Hui, Hon, Babusis, Darius, Brown, Brandon, Shih, I-hung, Feng, Joy Y., Ray, Adrian S., Mackman, Richard L.
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
Published in Bioorganic & medicinal chemistry letters (01.06.2013)
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Bifunctional inhibition of HIV-1 reverse transcriptase: A first step in designing a bifunctional triphosphate
Piao, Dongyuan, Basavapathruni, Aravind, Iyidogan, Pinar, Dai, Guangxiu, Hinz, Wolfgang, Ray, Adrian S., Murakami, Eisuke, Feng, Joy Y., You, Fei, Dutschman, Ginger E., Austin, David J., Parker, Kathlyn A., Anderson, Karen S.
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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GS-9219/VDC-1101 - a prodrug of the acyclic nucleotide PMEG has antitumor activity inspontaneous canine multiple myeloma
Thamm, Douglas H, Vail, David M, Kurzman, Ilene D, Babusis, Darius, Ray, Adrian S, Sousa-Powers, Noel, Tumas, Daniel B
Published in BMC veterinary research (25.01.2014)
Published in BMC veterinary research (25.01.2014)
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Effect of nucleoside and nucleotide reverse transcriptase inhibitors of HIV on endogenous nucleotide pools
VELA, Jennifer E, MILLER, Michael D, RHODES, Gerald R, RAY, Adrian S
Published in Antiviral therapy (01.01.2008)
Published in Antiviral therapy (01.01.2008)
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Lack of a metabolic and antiviral drug interaction between tenofovir, abacavir and lamivudine
RAY, Adrian S, MYRICK, Florence, VELA, Jennifer E, OLSON, Loren Y, EISENBERG, Eugene J, BORROTO-ESODA, Katyna, MILLER, Michael D, FRIDLAND, Arnold
Published in Antiviral therapy (01.01.2005)
Published in Antiviral therapy (01.01.2005)
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Exploring Integrin α5β1 as a Potential Therapeutic Target for Pulmonary Arterial Hypertension: Insights from Comprehensive Multicenter Preclinical Studies
Lemay, Sarah-Eve, Montesinos, Monica S, Grobs, Yann, Yokokawa, Tetsuro, Shimauchi, Tsukasa, Romanet, Charlotte, Sauvaget, Mélanie, Breuils-Bonnet, Sandra, Bourgeois, Alice, Théberge, Charlie, Pelletier, Andréanne, El Kabbout, Reem, Martineau, Sandra, Yamamoto, Keiko, Ray, Adrian S, Lippa, Blaise, Goodwin, Bryan, Lin, Fu-Yang, Wang, Hua, Dowling, James E, Lu, Min, Qiao, Qi, McTeague, T Andrew, Moy, Terence I, Potus, François, Provencher, Steeve, Boucherat, Olivier, Bonnet, Sébastien
Published in bioRxiv : the preprint server for biology (01.06.2024)
Published in bioRxiv : the preprint server for biology (01.06.2024)
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Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo(2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses
Siegel, Dustin, Hui, Hon C., Doerffler, Edward, Clarke, Michael O., Chun, Kwon, Zhang, Lijun, Neville, Sean, Carra, Ernest, Lew, Willard, Ross, Bruce, Wang, Queenie, Wolfe, Lydia, Jordan, Robert, Soloveva, Veronica, Knox, John, Perry, Jason, Perron, Michel, Stray, Kirsten M., Barauskas, Ona, Feng, Joy Y., Xu, Yili, Lee, Gary, Rheingold, Arnold L., Ray, Adrian S., Bannister, Roy, Strickley, Robert, Swaminathan, Swami, Lee, William A., Bavari, Sina, Cihlar, Tomas, Lo, Michael K., Warren, Travis K., Mackman, Richard L.
Published in Journal of medicinal chemistry (09.03.2017)
Published in Journal of medicinal chemistry (09.03.2017)
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