The IGF1R/INSR Inhibitor BI 885578 Selectively Inhibits Growth of IGF2-Overexpressing Colorectal Cancer Tumors and Potentiates the Efficacy of Anti-VEGF Therapy
Sanderson, Michael P, Hofmann, Marco H, Garin-Chesa, Pilar, Schweifer, Norbert, Wernitznig, Andreas, Fischer, Stefan, Jeschko, Astrid, Meyer, Reiner, Moll, Jürgen, Pecina, Thomas, Arnhof, Heribert, Weyer-Czernilofsky, Ulrike, Zahn, Stephan K, Adolf, Günther R, Kraut, Norbert
Published in Molecular cancer therapeutics (01.10.2017)
Published in Molecular cancer therapeutics (01.10.2017)
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BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis
Sanderson, Michael P, Apgar, Joshua, Garin-Chesa, Pilar, Hofmann, Marco H, Kessler, Dirk, Quant, Jens, Savchenko, Alexander, Schaaf, Otmar, Treu, Matthias, Tye, Heather, Zahn, Stephan K, Zoephel, Andreas, Haaksma, Eric, Adolf, Günther R, Kraut, Norbert
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
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BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity
RUDOLPH, Dorothea, STEEGMAIER, Martin, HOFFMANN, Matthias, GRAUERT, Matthias, BAUM, Anke, QUANT, Jens, HASLINGER, Christian, GARIN-CHESA, Pilar, ADOLF, Gunther R
Published in Clinical cancer research (01.05.2009)
Published in Clinical cancer research (01.05.2009)
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Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression
WIELENGA, V. J. M, HEIDER, K.-H, OFFERHAUS, G. J. A, ADOLF, G. R, VAN DEN BERG, F. M, PONTA, H, HERRLICH, P, PALS, S. T
Published in Cancer research (Chicago, Ill.) (15.10.1993)
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Published in Cancer research (Chicago, Ill.) (15.10.1993)
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BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo
Steegmaier, Martin, Hoffmann, Matthias, Baum, Anke, Lénárt, Péter, Petronczki, Mark, Krššák, Martin, Gürtler, Ulrich, Garin-Chesa, Pilar, Lieb, Simone, Quant, Jens, Grauert, Matthias, Adolf, Günther R., Kraut, Norbert, Peters, Jan-Michael, Rettig, Wolfgang J.
Published in Current biology (20.02.2007)
Published in Current biology (20.02.2007)
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A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation
Waizenegger, Irene C, Baum, Anke, Steurer, Steffen, Stadtmüller, Heinz, Bader, Gerd, Schaaf, Otmar, Garin-Chesa, Pilar, Schlattl, Andreas, Schweifer, Norbert, Haslinger, Christian, Colbatzky, Florian, Mousa, Sien, Kalkuhl, Arno, Kraut, Norbert, Adolf, Günther R
Published in Molecular cancer therapeutics (01.03.2016)
Published in Molecular cancer therapeutics (01.03.2016)
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Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia
Rudolph, Dorothea, Impagnatiello, Maria Antonietta, Blaukopf, Claudia, Sommer, Christoph, Gerlich, Daniel W, Roth, Mareike, Tontsch-Grunt, Ulrike, Wernitznig, Andreas, Savarese, Fabio, Hofmann, Marco H, Albrecht, Christoph, Geiselmann, Lena, Reschke, Markus, Garin-Chesa, Pilar, Zuber, Johannes, Moll, Jürgen, Adolf, Günther R, Kraut, Norbert
Published in The Journal of pharmacology and experimental therapeutics (01.03.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2015)
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Lebenshaltung des Mittelstandes: Statistische und theoretische Untersuchungen zur Konsumtionslehre. Mit e. Beitrag von Heinrich Neumann. Untersuchungen über Preisbildung. Abt. C: Kosten der Lebenshaltung. II. Teil. Hrsg. von F. Eulenburg. (Schriften des Vereins für Sozialpolitik 146-II)
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A novel Fc-engineered monoclonal antibody to CD37 with enhanced ADCC and high proapoptotic activity for treatment of B-cell malignancies
Heider, Karl-Heinz, Kiefer, Kerstin, Zenz, Thorsten, Volden, Matthias, Stilgenbauer, Stephan, Ostermann, Elinborg, Baum, Anke, Lamche, Herbert, Küpcü, Zaruhi, Jacobi, Alexander, Müller, Steffen, Hirt, Ulrich, Adolf, Günther R., Borges, Eric
Published in Blood (13.10.2011)
Published in Blood (13.10.2011)
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Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases
Sini, Patrizia, Gürtler, Ulrich, Zahn, Stephan K, Baumann, Christoph, Rudolph, Dorothea, Baumgartinger, Rosa, Strauss, Eva, Haslinger, Christian, Tontsch-Grunt, Ulrike, Waizenegger, Irene C, Solca, Flavio, Bader, Gerd, Zoephel, Andreas, Treu, Matthias, Reiser, Ulrich, Garin-Chesa, Pilar, Boehmelt, Guido, Kraut, Norbert, Quant, Jens, Adolf, Günther R
Published in Molecular cancer therapeutics (01.10.2016)
Published in Molecular cancer therapeutics (01.10.2016)
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Efficacy of the highly selective focal adhesion kinase inhibitor BI 853520 in adenocarcinoma xenograft models is linked to a mesenchymal tumor phenotype
Hirt, Ulrich A., Waizenegger, Irene C., Schweifer, Norbert, Haslinger, Christian, Gerlach, Daniel, Braunger, Jürgen, Weyer-Czernilofsky, Ulrike, Stadtmüller, Heinz, Sapountzis, Ioannis, Bader, Gerd, Zoephel, Andreas, Bister, Bojan, Baum, Anke, Quant, Jens, Kraut, Norbert, Garin-Chesa, Pilar, Adolf, Günther R.
Published in Oncogenesis (New York, NY) (23.02.2018)
Published in Oncogenesis (New York, NY) (23.02.2018)
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HLA class II induction in human islet cells by interferon-gamma plus tumour necrosis factor or lymphotoxin
Pujol-Borrell, R, Todd, I, Doshi, M, Bottazzo, G F, Sutton, R, Gray, D, Adolf, G R, Feldmann, M
Published in Nature (London) (19.03.1987)
Published in Nature (London) (19.03.1987)
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Prognostic value of CD44 splice variant expression in ovarian cancer
Uhl-Steidl, M, Müller-Holzner, E, Zeimet, A G, Adolf, G R, Daxenbichler, G, Marth, C, Dapunt, O
Published in Oncology (01.09.1995)
Published in Oncology (01.09.1995)
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Tumor targeting properties of monoclonal antibodies with different affinity for target antigen CD44V6 in nude mice bearing head‐and‐neck cancer xenografts
Verel, Iris, Heider, Karl‐Heinz, Siegmund, Miranda, Ostermann, Elínborg, Patzelt, Erik, Sproll, Marlies, Snow, Gordon B., Adolf, Günther R., van Dongen, Guus A.M.S.
Published in International journal of cancer (20.05.2002)
Published in International journal of cancer (20.05.2002)
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Comparison of immunohistochemistry and RT-PCR for detection of CD44v-expression, a new prognostic factor in human breast cancer
Dall, P, Heider, K H, Sinn, H P, Skroch-Angel, P, Adolf, G, Kaufmann, M, Herrlich, P, Ponta, H
Published in International journal of cancer (08.02.1995)
Published in International journal of cancer (08.02.1995)
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Pharmacodynamic and antineoplastic activity of BI 836845, a fully human IGF ligand-neutralizing antibody, and mechanistic rationale for combination with rapamycin
Friedbichler, Katrin, Hofmann, Marco H, Kroez, Monika, Ostermann, Elinborg, Lamche, Herbert R, Koessl, Christian, Borges, Eric, Pollak, Michael N, Adolf, Günther, Adam, Paul J
Published in Molecular cancer therapeutics (01.02.2014)
Published in Molecular cancer therapeutics (01.02.2014)
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Identification and characterization of 9D7, a novel human protein overexpressed in renal cell carcinoma
Klade, Christoph S., Dohnal, Alexander, Fürst, Walter, Sommergruber, Wolfgang, Heider, Karl‐Heinz, Gharwan, Helen, Ratschek, Manfred, Adolf, Günther R.
Published in International journal of cancer (10.01.2002)
Published in International journal of cancer (10.01.2002)
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