Development of Dolutegravir Single-entity and Fixed-dose Combination Formulations for Children
Singh, Rajendra P, Adkison, Kimberly K, Baker, Mark, Parasrampuria, Ridhi, Wolstenholme, Allen, Davies, Mark, Sewell, Nicola, Brothers, Cindy, Buchanan, Ann M
Published in The Pediatric infectious disease journal (01.03.2022)
Published in The Pediatric infectious disease journal (01.03.2022)
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Pharmacokinetic and pharmacokinetic/pharmacodynamic characterization of the dolutegravir/rilpivirine two‐drug regimen in SWORD‐1/‐2 phase 3 studies
Mehta, Rashmi, Lagishetty, Chakradhar V., Angelis, Konstantinos, Aylott, Alicia, Kahl, Lesley, Blair, Libby, Matthews, Jessica, Wynne, Brian, Crauwels, Herta, Underwood, Mark, Adkison, Kimberly K.
Published in British journal of clinical pharmacology (01.07.2023)
Published in British journal of clinical pharmacology (01.07.2023)
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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance
Ring, Barbara J., Chien, Jenny Y., Adkison, Kimberly K., Jones, Hannah M., Rowland, Malcolm, Jones, Rhys Do, Yates, James W.T., Ku, M. Sherry, Gibson, Christopher R., He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick
Published in Journal of pharmaceutical sciences (01.10.2011)
Published in Journal of pharmaceutical sciences (01.10.2011)
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PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach
Poulin, Patrick, Jones, Rhys D.O., Jones, Hannah M., Gibson, Christopher R., Rowland, Malcolm, Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Yates, James W.T.
Published in Journal of pharmaceutical sciences (01.10.2011)
Published in Journal of pharmaceutical sciences (01.10.2011)
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Journal Article
Effect of Sorbitol on the Pharmacokinetic Profile of Lamivudine Oral Solution in Adults: An Open‐Label, Randomized Study
Adkison, Kimberly, Wolstenholme, Allen, Lou, Yu, Zhang, Zhiping, Eld, Amy, Perger, Teodora, Vangerow, Harald, Hayward, Katy, Shaefer, Mark, McCoig, Cynthia
Published in Clinical pharmacology and therapeutics (01.03.2018)
Published in Clinical pharmacology and therapeutics (01.03.2018)
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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 2: Comparative assessment of prediction methods of human volume of distribution
Jones, Rhys Do, Jones, Hannah M., Rowland, Malcolm, Gibson, Christopher R., Yates, James W.T., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick
Published in Journal of pharmaceutical sciences (01.10.2011)
Published in Journal of pharmaceutical sciences (01.10.2011)
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Passive Permeability and P-Glycoprotein-Mediated Efflux Differentiate Central Nervous System (CNS) and Non-CNS Marketed Drugs
Mahar Doan, Kelly M, Humphreys, Joan E, Webster, Lindsey O, Wring, Stephen A, Shampine, Larry J, Serabjit-Singh, Cosette J, Adkison, Kimberly K, Polli, Joseph W
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2002)
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PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 4: Prediction of plasma concentration–time profiles in human from in vivo preclinical data by using the Wajima approach
Vuppugalla, Ragini, Marathe, Punit, He, Handan, Jones, Rhys D.O., Yates, James W.T., Jones, Hannah M., Gibson, Christopher R., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., Ku, M. Sherry, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Poulin, Patrick
Published in Journal of pharmaceutical sciences (01.10.2011)
Published in Journal of pharmaceutical sciences (01.10.2011)
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Journal Article
PhRMA CPCDC Initiative on Predictive Models of Human Pharmacokinetics, Part 1: Goals, Properties of the Phrma Dataset, and Comparison with Literature Datasets
Poulin, Patrick, Jones, Hannah M., Jones, Rhys Do, Yates, James W.T., Gibson, Christopher R., Chien, Jenny Y., Ring, Barbara J., Adkison, Kimberly K., He, Handan, Vuppugalla, Ragini, Marathe, Punit, Fischer, Volker, Dutta, Sandeep, Sinha, Vikash K., Björnsson, Thorir, Lavé, Thierry, Sherry Ku, M.
Published in Journal of pharmaceutical sciences (01.10.2011)
Published in Journal of pharmaceutical sciences (01.10.2011)
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Oral Sulfasalazine as a Clinical BCRP Probe Substrate: Pharmacokinetic Effects of Genetic Variation (C421A) and Pantoprazole Coadministration
Adkison, Kimberly K., Vaidya, Soniya S., Lee, Daniel Y., Koo, Seok Hwee, Li, Linghui, Mehta, Amar A., Gross, Annette S., Polli, Joseph W., Humphreys, Joan E., Lou, Yu, Lee, Edmund J.D.
Published in Journal of pharmaceutical sciences (01.02.2010)
Published in Journal of pharmaceutical sciences (01.02.2010)
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Pharmacokinetics of hepatitis C virus NS5A inhibitor JNJ-56914845 (GSK2336805) in subjects with hepatic impairment
Adkison, Kimberly K, Gan, Jianjun, Elko-Simms, Lucinda, Gardner, Stephen, Dumont, Etienne, Jones, Lori S, Saunders, Joanne, Marbury, Thomas, Smith, William, Berg, Jolene, Galloway, Christopher, Stump, Patrick J
Published in Journal of clinical pharmacology (01.09.2015)
Published in Journal of clinical pharmacology (01.09.2015)
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Antiviral activity and safety of 873140, a novel CCR5 antagonist, during short-term monotherapy in HIV-infected adults
LALEZARI, Jacob, THOMPSON, Melanie, BERREY, Michelle, PISCITELLI, Stephen, KUMAR, Priny, PILIERO, Peter, DAVEY, Richard, PATTERSON, Kristine, SHACHOY-CLARK, Anne, ADKISON, Kimberly, DEMAREST, James, YU LOU
Published in AIDS (London) (23.09.2005)
Published in AIDS (London) (23.09.2005)
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The ABCG2 C421A polymorphism does not affect oral nitrofurantoin pharmacokinetics in healthy Chinese male subjects
Adkison, Kimberly K., Vaidya, Soniya S., Lee, Daniel Y., Koo, Seok Hwee, Li, Linghui, Mehta, Amar A., Gross, Annette S., Polli, Joseph W., Lou, Yu, Lee, Edmund J. D.
Published in British journal of clinical pharmacology (01.08.2008)
Published in British journal of clinical pharmacology (01.08.2008)
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Journal Article
Effects of omeprazole and ritonavir on absorption and elimination of the hepatitis C virus NS5A inhibitor GSK2336805 in healthy adults
Adkison, Kimberly K., Jones, Lori S., Lou, Yu, Gan, Jianjun, Wilfret, David A.
Published in Clinical pharmacology in drug development (01.09.2014)
Published in Clinical pharmacology in drug development (01.09.2014)
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Journal Article
Pharmacokinetics and Short-Term Safety of 873140, a Novel CCR5 Antagonist, in Healthy Adult Subjects
Adkison, Kimberly K, Shachoy-Clark, Anne, Fang, Lei, Lou, Yu, O'Mara, Kathy, Berrey, M. Michelle, Piscitelli, Stephen C
Published in Antimicrobial Agents and Chemotherapy (01.07.2005)
Published in Antimicrobial Agents and Chemotherapy (01.07.2005)
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Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing heterobiaryl carboxylic acids
Shearer, Barry G., Chao, Esther Y., Uehling, David E., Deaton, David N., Cowan, Conrad, Sherman, Bryan W., Milliken, Tula, Faison, Walter, Brown, Kathleen, Adkison, Kimberly K., Lee, Frank
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
Published in Bioorganic & medicinal chemistry letters (15.08.2007)
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In vitro and clinical investigation of the relationship between CCR5 receptor occupancy and anti-HIV activity of Aplaviroc
Demarest, James F, Sparks, Sara S, Schell, Kathleen, Shibayama, Shiro, McDanal, Charlene B, Fang, Lei, Adkison, Kimberly K, Shachoy-Clark, Anne, Piscitelli, Stephen C
Published in Journal of clinical pharmacology (01.10.2008)
Published in Journal of clinical pharmacology (01.10.2008)
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The effects of ritonavir and lopinavir/ritonavir on the pharmacokinetics of a novel CCR5 antagonist, aplaviroc, in healthy subjects
Adkison, Kimberly K., Shachoy‐Clark, Anne, Fang, Lei, Lou, Yu, Otto, Vicky R., Berrey, M. Michelle, Piscitelli, Stephen C.
Published in British journal of clinical pharmacology (01.09.2006)
Published in British journal of clinical pharmacology (01.09.2006)
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Journal Article
Evaluation of the drug interaction potential of aplaviroc, a novel human immunodeficiency virus entry inhibitor, using a modified cooperstown 5 + 1 cocktail
Johnson, Brendan M, Song, Ivy H, Adkison, Kimberly K, Borland, Julie, Fang, Lei, Lou, Yu, Berrey, M Michelle, Nafziger, Anne N, Piscitelli, Stephen C, Bertino, Jr, Joseph S
Published in Journal of clinical pharmacology (01.05.2006)
Published in Journal of clinical pharmacology (01.05.2006)
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