Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection
Jacobson, Ira M, McHutchison, John G, Dusheiko, Geoffrey, Di Bisceglie, Adrian M, Reddy, K. Rajender, Bzowej, Natalie H, Marcellin, Patrick, Muir, Andrew J, Ferenci, Peter, Flisiak, Robert, George, Jacob, George, Shelley, Rizzetto, Mario, Shouval, Daniel, Sola, Ricard, Terg, Ruben A, Yoshida, Eric M, Adda, Nathalie, Bengtsson, Leif, Sankoh, Abdul J, Kieffer, Tara L, Kauffman, Robert S, M.D, Stefan Zeuzem
Published in The New England journal of medicine (23.06.2011)
Published in The New England journal of medicine (23.06.2011)
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Response-Guided Telaprevir Combination Treatment for Hepatitis C Virus Infection
Sherman, Kenneth E, Flamm, Steven L, Afdhal, Nezam H, Nelson, David R, Sulkowski, Mark S, Everson, Gregory T, Fried, Michael W, Adler, Michael, Reesink, Hendrik W, Martin, Marie, Sankoh, Abdul J, Adda, Nathalie, Kauffman, Robert S, George, Shelley, Wright, Christopher I, Poordad, Fred
Published in The New England journal of medicine (15.09.2011)
Published in The New England journal of medicine (15.09.2011)
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Evolution of Treatment-Emergent Resistant Variants in Telaprevir Phase 3 Clinical Trials
Sullivan, James C., De Meyer, Sandra, Bartels, Doug J., Dierynck, Inge, Zhang, Eileen Z., Spanks, Joan, Tigges, Ann M., Ghys, Anne, Dorrian, Jennifer, Adda, Nathalie, Martin, Emily C., Beumont, Maria, Jacobson, Ira M., Sherman, Kenneth E., Zeuzem, Stefan, Picchio, Gaston, Kieffer, Tara L.
Published in Clinical infectious diseases (15.07.2013)
Published in Clinical infectious diseases (15.07.2013)
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Safety and immunogenicity of the therapeutic vaccine TG1050 in chronic hepatitis B patients: a phase 1b placebo-controlled trial
Zoulim, Fabien, Fournier, Claire, Habersetzer, François, Sprinzl, Martin, Pol, Stanislas, Coffin, Carla S, Leroy, Vincent, Ma, Mang, Wedemeyer, Heiner, Lohse, Ansgar W, Thimme, Robert, Lugardon, Karine, Martin, Perrine, Bastien, Bérangère, Sansas, Benoit, Adda, Nathalie, Halluard, Celine, Bendjama, Kaïdre, Brandely, Maud, Inchauspé, Geneviève
Published in Human vaccines & immunotherapeutics (01.02.2020)
Published in Human vaccines & immunotherapeutics (01.02.2020)
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Hepatitis C viral evolution in genotype 1 treatment-naïve and treatment-experienced patients receiving telaprevir-based therapy in clinical trials
Kieffer, Tara L, De Meyer, Sandra, Bartels, Doug J, Sullivan, James C, Zhang, Eileen Z, Tigges, Ann, Dierynck, Inge, Spanks, Joan, Dorrian, Jennifer, Jiang, Min, Adiwijaya, Bambang, Ghys, Anne, Beumont, Maria, Kauffman, Robert S, Adda, Nathalie, Jacobson, Ira M, Sherman, Kenneth E, Zeuzem, Stefan, Kwong, Ann D, Picchio, Gaston
Published in PloS one (12.04.2012)
Published in PloS one (12.04.2012)
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Pharmacokinetics of Tenofovir Disoproxil Fumarate and Ritonavir-Boosted Saquinavir Mesylate Administered Alone or in Combination at Steady State
CHITTICK, Gregory E, JIAN ZONG, BLUM, M. Robert, SORBEL, Jeffrey J, BEGLEY, John A, ADDA, Nathalie, KEARNEY, Brian P
Published in Antimicrobial Agents and Chemotherapy (01.04.2006)
Published in Antimicrobial Agents and Chemotherapy (01.04.2006)
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EDP-938, a Respiratory Syncytial Virus Inhibitor, in a Human Virus Challenge
Ahmad, Alaa, Eze, Kingsley, Noulin, Nicolas, Horvathova, Veronika, Murray, Bryan, Baillet, Mark, Grey, Laura, Mori, Julie, Adda, Nathalie
Published in The New England journal of medicine (17.02.2022)
Published in The New England journal of medicine (17.02.2022)
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EDP-305 in patients with NASH: A phase II double-blind placebo-controlled dose-ranging study
Ratziu, Vlad, Rinella, Mary E., Neuschwander-Tetri, Brent A., Lawitz, Eric, Denham, Douglas, Kayali, Zeid, Sheikh, Aasim, Kowdley, Kris V., Desta, Taddese, Elkhashab, Magdy, DeGrauw, Jeffery, Goodwin, Bryan, Ahmad, Alaa, Adda, Nathalie
Published in Journal of hepatology (01.03.2022)
Published in Journal of hepatology (01.03.2022)
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SAT440 - EDP-514, a novel pangenotypic class II hepatitis B virus core inhibitor: preliminary results of a phase 1 study in healthy adult subjects
Larson, Kajal, Ahmad, Alaa, Coakley, Eoin, Chai, Jingwen, Dickerson, Daniel, Adda, Nathalie
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
EDP-514, a novel pangenotypic class II hepatitis B virus core inhibitor: preliminary results of a phase 1 study in healthy adult subjects
Larson, Kajal, Ahmad, Alaa, Coakley, Eoin, Chai, Jingwen, Dickerson, Daniel, Adda, Nathalie
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Combination therapy with telaprevir for chronic hepatitis C virus genotype 1 infection in patients with HIV: a randomized trial
Sulkowski, Mark S, Sherman, Kenneth E, Dieterich, Douglas T, Bsharat, Mohammad, Mahnke, Lisa, Rockstroh, Jürgen K, Gharakhanian, Shahin, McCallister, Scott, Henshaw, Joshua, Girard, Pierre-Marie, Adiwijaya, Bambang, Garg, Varun, Rubin, Raymond A, Adda, Nathalie, Soriano, Vincent
Published in Annals of internal medicine (16.07.2013)
Published in Annals of internal medicine (16.07.2013)
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Journal Article
Telaprevir for Previously Treated Chronic HCV Infection
McHutchison, John G, Manns, Michael P, Muir, Andrew J, Terrault, Norah A, Jacobson, Ira M, Afdhal, Nezam H, Heathcote, E. Jenny, Zeuzem, Stefan, Reesink, Hendrik W, Garg, Jyotsna, Bsharat, Mohammad, George, Shelley, Kauffman, Robert S, Adda, Nathalie, M.D, Adrian M. Di Bisceglie
Published in The New England journal of medicine (08.04.2010)
Published in The New England journal of medicine (08.04.2010)
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Journal Article
EDP-514, a potent pangenotypic class II hepatitis B virus core inhibitor, demonstrates significant HBV DNA and HBV RNA reductions in a phase 1b study in viremic, chronic hepatitis B patients
Yuen, Man-Fung, Chuang, Wan-Long, Peng, Cheng-Yuan, Jeng, Rachel Wen-Juei, Su, Wei-Wen, Chang, Ting-Tsung, Chen, Chi-Yi, Hsu, Yao-Chun, De Rosa La, Guy, Ahmad, Alaa, Luo, Ed, Conery, Annie, Adda, Nathalie
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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EDP-514, a novel pangenotypic class II hepatitis B virus core inhibitor: final results of a 28-day phase 1b study in nuc-suppressed chronic hepatitis B patients
Feld, Jordan, Lawitz, Eric, Nguyen, Tuan T, Lalezari, Jacob P, Hassanein, Tarek, Martin, Paul, Han, Steven-Huy B, Dieterich, Douglas T, Giard, Jeanne-Marie, De La Rosa, Guy, Ahmad, Alaa, Luo, Ed, Conery, Annie, Adda, Nathalie
Published in Journal of hepatology (01.07.2022)
Published in Journal of hepatology (01.07.2022)
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Journal Article
EDP-514 in healthy subjects and nucleos(t)ide reverse transcriptase inhibitor-suppressed patients with chronic hepatitis B
Feld, Jordan J, Lawitz, Eric, Nguyen, Tuan, Lalezari, Jacob, Hassanein, Tarek, Martin, Paul, Han, Steven-Huy, Dieterich, Douglas, Giard, Jeanne-Marie, De La Rosa, Guy, Ahmad, Alaa, Luo, Ed, Conery, Annie L, Adda, Nathalie
Published in Antiviral therapy (01.12.2022)
Published in Antiviral therapy (01.12.2022)
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EDP-305, a non-bile acid farnesoid X receptor (FXR) agonist, showed statistically significant improvements in liver biochemistry and hepatic steatosis in the phase 2a argon-1 study
Ratziu, Vlad, Rinella, Mary, Tetri, Brent, Lawitz, Eric, Denham, Douglas, Kayali, Zeid, Sheikh, Aasim, Kowdley, Kris V., Desta, Taddese, Elkhashab, Magdy, DeGrauw, Jeffery, Ahmad, Alaa, Larson, Kajal, McClure, Ty, Adda, Nathalie
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
AS078 - EDP-305, a non-bile acid farnesoid X receptor (FXR) agonist, showed statistically significant improvements in liver biochemistry and hepatic steatosis in the phase 2a argon-1 study
Ratziu, Vlad, Rinella, Mary, Tetri, Brent, Lawitz, Eric, Denham, Douglas, Kayali, Zeid, Sheikh, Aasim, Kowdley, Kris V., Desta, Taddese, Elkhashab, Magdy, DeGrauw, Jeffery, Ahmad, Alaa, Larson, Kajal, McClure, Ty, Adda, Nathalie
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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