Discovery of nonsteroidal glucocorticoid receptor ligands based on 6-indole-1,2,3,4-tetrahydroquinolines
Roach, Steven L., Higuchi, Robert I., Adams, Mark E., Liu, Yan, Karanewsky, Donald S., Marschke, Keith B., Mais, Dale E., Miner, Jeffrey N., Zhi, Lin
Published in Bioorganic & medicinal chemistry (15.06.2008)
Published in Bioorganic & medicinal chemistry (15.06.2008)
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Journal Article
Synthesis and Characterization of Nonsteroidal Glucocorticoid Receptor Modulators for Multiple Myeloma
Hudson, Andrew R, Roach, Steven L, Higuchi, Robert I, Phillips, Dean P, Bissonnette, Reid P, Lamph, William W, Yen, Jean, Li, Yongkai, Adams, Mark E, Valdez, Lino J, Vassar, Angie, Cuervo, Catalina, Kallel, E. Adam, Gharbaoui, Catherine J, Mais, Dale E, Miner, Jeffrey N, Marschke, Keith B, Rungta, Deepa, Negro-Vilar, Andrés, Zhi, Lin
Published in Journal of medicinal chemistry (20.09.2007)
Published in Journal of medicinal chemistry (20.09.2007)
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Journal Article
Structure-based design and synthesis of pyrrole derivatives as MEK inhibitors
Wallace, Michael B., Adams, Mark E., Kanouni, Toufike, Mol, Clifford D., Dougan, Douglas R., Feher, Victoria A., O’Connell, Shawn M., Shi, Lihong, Halkowycz, Petro, Dong, Qing
Published in Bioorganic & medicinal chemistry letters (15.07.2010)
Published in Bioorganic & medicinal chemistry letters (15.07.2010)
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Journal Article
The Folded Modules of Aggrecan G3 Domain Exert Two Separable Functions in Glycosaminoglycan Modification and Product Secretion
Chen, Liwen, Wu, Yaojiong, Lee, Vivian, Kiani, Chris, Adams, Mark E., Yao, Yeqi, Yang, Burton B.
Published in The Journal of biological chemistry (25.01.2002)
Published in The Journal of biological chemistry (25.01.2002)
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Journal Article
Design and synthesis of orally available MEK inhibitors with potent in vivo antitumor efficacy
Adams, Mark E., Wallace, Michael B., Kanouni, Toufike, Scorah, Nicholas, O’Connell, Shawn M., Miyake, Hiroshi, Shi, Lihong, Halkowycz, Petro, Zhang, Lilly, Dong, Qing
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Journal Article
Cleavage of the Carboxyl Tail from the G3 Domain of Aggrecan but Not Versican and Identification of the Amino Acids Involved in the Degradation
Lee, Vivian, Chen, Liwen, Paiwand, Frouz, Cao, Liu, Wu, Yaojiong, Inman, Robert, Adams, Mark E., Yang, Burton B.
Published in The Journal of biological chemistry (21.06.2002)
Published in The Journal of biological chemistry (21.06.2002)
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Journal Article
Tetrahydroquinoline glucocorticoid receptor agonists: Discovery of a 3-hydroxyl for improving receptor selectivity
Roach, Steven L., Higuchi, Robert I., Hudson, Andrew R., Adams, Mark E., Syka, Peter M., Mais, Dale E., Miner, Jeffrey N., Marschke, Keith B., Zhi, Lin
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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Journal Article
Discovery of orally available tetrahydroquinoline-based glucocorticoid receptor agonists
Hudson, Andrew R., Higuchi, Robert I., Roach, Steven L., Adams, Mark E., Vassar, Angela, Syka, Peter M., Mais, Dale E., Miner, Jeffrey N., Marschke, Keith B., Zhi, Lin
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Journal Article
Nonsteroidal 2,3-dihydroquinoline glucocorticoid receptor agonists with reduced PEPCK activation
Hudson, Andrew R., Higuchi, Robert I., Roach, Steven L., Valdez, Lino J., Adams, Mark E., Vassar, Angie, Rungta, Deepa, Syka, Peter M., Mais, Dale E., Marschke, Keith B., Zhi, Lin
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Journal Article
β1-Integrin–collagen interaction reduces chondrocyte apoptosis
Cao, Liu, Lee, Vivian, Adams, Mark E, Kiani, Chris, Zhang, Yaou, Hu, Wendy, Yang, Burton B
Published in Matrix biology (01.08.1999)
Published in Matrix biology (01.08.1999)
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Journal Article
Potent, nonsteroidal selective androgen receptor modulators (SARMs) based on 8H-[1,4 ]oxazino [2,3 -f] quinolin-8-ones
HIGUCHI, Robert I, THOMPSON, Anthony W, ADAM KALLEL, E, KARANEWSKY, Donald S, SCHRADER, William T, MARSCHKE, Keith B, LIN ZHI, CHEN, Jyun-Hung, CAFERRO, Thomas R, CUMMINGS, Marquis L, DECKHUT, Charlotte P, ADAMS, Mark E, TEGLEY, Christopher M, EDWARDS, James P, LOPEZ, Francisco J
Published in Bioorganic & medicinal chemistry letters (01.10.2007)
Published in Bioorganic & medicinal chemistry letters (01.10.2007)
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Journal Article
Tandem Repeats Are Involved in G1 Domain Inhibition of Versican Expression and Secretion and the G3 Domain Enhances Glycosaminoglycan Modification and Product Secretion via the Complement-binding Protein-like Motif
Yang, Bing L., Cao, Liu, Kiani, Chris, Lee, Vivian, Zhang, Yaou, Adams, Mark E., Yang, Burton B.
Published in The Journal of biological chemistry (14.07.2000)
Published in The Journal of biological chemistry (14.07.2000)
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Journal Article
Identification of the Motif in Versican G3 Domain That Plays a Dominant-negative Effect on Astrocytoma Cell Proliferation through Inhibiting Versican Secretion and Binding
Wu, Y, Zhang, Y, Cao, L, Chen, L, Lee, V, Zheng, P S, Kiani, C, Adams, M E, Ang, L C, Paiwand, F, Yang, B B
Published in The Journal of biological chemistry (27.04.2001)
Published in The Journal of biological chemistry (27.04.2001)
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Journal Article
Versican Modulates Embryonic Chondrocyte Morphology via the Epidermal Growth Factor-like Motifs in G3
Zhang, Yaou, Wu, Yaojiong, Cao, Liu, Lee, Vivian, Chen, Liwen, Lin, Zhaosheng, Kiani, Chris, Adams, Mark E., Yang, Burton B.
Published in Experimental cell research (01.02.2001)
Published in Experimental cell research (01.02.2001)
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Journal Article
Identification of the Motifs and Amino Acids in Aggrecan G1 and G2 Domains Involved in Product Secretion
Kiani, Chris, Chen, Liwen, Lee, Vivian, Zheng, Peng-Sheng, Wu, Yaojiong, Wen, Jianping, Cao, Liu, Adams, Mark E., Sheng, Wang, Yang, Burton B.
Published in Biochemistry (Easton) (17.06.2003)
Published in Biochemistry (Easton) (17.06.2003)
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Journal Article
GPR6 PYRAZINES MODULATORS OF GPR6
ADAMS MARK E, KIKUCHI SHOTA, LAM BETTY, SUN HUIKAI, REICHARD HOLLY, HOPKINS MARIA, MONENSCHEIN HOLGER, HITCHCOCK STEPHEN, BROWN JASON W
Year of Publication 21.10.2016
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Year of Publication 21.10.2016
Patent
Subtotal Parathyroidectomy in Renal Failure: Still Needed after All These Years
Decker, P. Anthony, Cohen, Eric P., Doffek, Kara M., Ashley, Blake A., Bienemann, Mary E., Zhu, Yong Ran, Adams, Mark E., Wilson, Stuart D., Demeure, Michael J.
Published in World journal of surgery (01.06.2001)
Published in World journal of surgery (01.06.2001)
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Journal Article
Probing the catalytic properties of copper(II) complexes of appended cyclams: correlations between catalysis and stability constants or electrochemical properties
Malachowski, Mitchell R, Dorsey, Brian T, Parker, Michael J, Adams, Mark E, Kelly, Richard S
Published in Polyhedron (01.01.1998)
Published in Polyhedron (01.01.1998)
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