Metabolism, Excretion, and Pharmacokinetics of [14C]INCB018424, a Selective Janus Tyrosine Kinase 1/2 Inhibitor, in Humans
SHILLING, Adam D, NEDZA, Frank M, SHEPARD, Stacey, RODGERS, James, YUE, Tai-Yuen, YELESWARAM, Swamy, EMM, Thomas, DIAMOND, Sharon, MCKEEVER, Edward, PUNWANI, Naresh, WILLIAMS, William, ARVANITIS, Argyrios, GALYA, Laurine G, MEI LI
Published in Drug metabolism and disposition (01.11.2010)
Published in Drug metabolism and disposition (01.11.2010)
Get full text
Journal Article
Structure-Based Optimization of Protein Tyrosine Phosphatase 1B Inhibitors: From the Active Site to the Second Phosphotyrosine Binding Site
Wilson, Douglas P, Wan, Zhao-Kui, Xu, Wei-Xin, Kirincich, Steven J, Follows, Bruce C, Joseph-McCarthy, Diane, Foreman, Kenneth, Moretto, Alessandro, Wu, Junjun, Zhu, Min, Binnun, Eva, Zhang, Yan-Ling, Tam, May, Erbe, David V, Tobin, James, Xu, Xin, Leung, Louis, Shilling, Adam, Tam, Steve Y, Mansour, Tarek S, Lee, Jinbo
Published in Journal of medicinal chemistry (20.09.2007)
Published in Journal of medicinal chemistry (20.09.2007)
Get full text
Journal Article
Synthesis and Biological Evaluation of Quinoline Salicylic Acids As P-Selectin Antagonists
Kaila, Neelu, Janz, Kristin, DeBernardo, Silvano, Bedard, Patricia W, Camphausen, Raymond T, Tam, Steve, Tsao, Desirée H. H, Keith, James C, Nickerson-Nutter, Cheryl, Shilling, Adam, Young-Sciame, Ruth, Wang, Qin
Published in Journal of medicinal chemistry (11.01.2007)
Published in Journal of medicinal chemistry (11.01.2007)
Get full text
Journal Article
Using a homology model of cytochrome P450 2D6 to predict substrate site of metabolism
Unwalla, Rayomand J., Cross, Jason B., Salaniwal, Sumeet, Shilling, Adam D., Leung, Louis, Kao, John, Humblet, Christine
Published in Journal of computer-aided molecular design (01.03.2010)
Published in Journal of computer-aided molecular design (01.03.2010)
Get full text
Journal Article
Synthesis, Potency, and in Vivo Evaluation of 2-Piperazin-1-ylquinoline Analogues as Dual Serotonin Reuptake Inhibitors and Serotonin 5-HT1A Receptor Antagonists
Zhou, Dahui, Stack, Gary P, Lo, Jennifer, Failli, Amedeo A, Evrard, Deborah A, Harrison, Boyd L, Hatzenbuhler, Nicole T, Tran, Megan, Croce, Susan, Yi, Soo, Golembieski, Jeannette, Hornby, Geoffrey A, Lai, Margaret, Lin, Qian, Schechter, Lee E, Smith, Deborah L, Shilling, Adam D, Huselton, Christine, Mitchell, Paul, Beyer, Chad E, Andree, Terrance H
Published in Journal of medicinal chemistry (13.08.2009)
Published in Journal of medicinal chemistry (13.08.2009)
Get full text
Journal Article
Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective α2A-adrenoceptor antagonism
Dwyer, Jason M., Platt, Brian J., Sukoff Rizzo, Stacey J., Pulicicchio, Claudine M., Wantuch, Caitlin, Zhang, Mei-Yi, Cummons, Terri, Leventhal, Liza, Bender, Corey N., Zhang, Jean, Kowal, Dianne, Lu, Shendi, Rajarao, S. Johannes R., Smith, Deborah L., Shilling, Adam D., Wang, Jianyao, Butera, John, Resnick, Lynn, Rosenzweig-Lipson, Sharon, Schechter, Lee E., Beyer, Chad E.
Published in The international journal of neuropsychopharmacology (01.10.2010)
Published in The international journal of neuropsychopharmacology (01.10.2010)
Get full text
Journal Article
Desvenlafaxine and venlafaxine exert minimal in vitro inhibition of human cytochrome P450 and P-glycoprotein activities
Oganesian, Aram, Shilling, Adam D, Young-Sciame, Ruth, Tran, Judy, Watanyar, Adiba, Azam, Farooq, Kao, John, Leung, Louis
Published in Psychopharmacology bulletin (2009)
Get more information
Published in Psychopharmacology bulletin (2009)
Journal Article
Synthesis, Potency, and in Vivo Evaluation of 2-Piperazin-1-ylquinoline Analogues as Dual Serotonin Reuptake Inhibitors and Serotonin 5-HT 1A Receptor Antagonists
Zhou, Dahui, Stack, Gary P., Lo, Jennifer, Failli, Amedeo A., Evrard, Deborah A., Harrison, Boyd L., Hatzenbuhler, Nicole T., Tran, Megan, Croce, Susan, Yi, Soo, Golembieski, Jeannette, Hornby, Geoffrey A., Lai, Margaret, Lin, Qian, Schechter, Lee E., Smith, Deborah L., Shilling, Adam D., Huselton, Christine, Mitchell, Paul, Beyer, Chad E., Andree, Terrance H.
Published in Journal of medicinal chemistry (13.08.2009)
Published in Journal of medicinal chemistry (13.08.2009)
Get full text
Journal Article
Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective [alpha]2A-adrenoceptor antagonism
Dwyer, Jason M, Platt, Brian J, Sukoff Rizzo, Stacey J, Pulicicchio, Claudine M, Wantuch, Caitlin, Zhang, Mei-Yi, Cummons, Terri, Leventhal, Liza, Bender, Corey N, Zhang, Jean, Kowal, Dianne, Lu, Shendi, Rajarao, S Johannes R, Smith, Deborah L, Shilling, Adam D, Wang, Jianyao, Butera, John, Resnick, Lynn, Rosenzweig-Lipson, Sharon, Schechter, Lee E, Beyer, Chad E
Published in The international journal of neuropsychopharmacology (01.10.2010)
Published in The international journal of neuropsychopharmacology (01.10.2010)
Get full text
Journal Article
Structure-based optimization of protein tyrosine phosphatase 1Β inhibitors : From the active site to the second phosphotyrosine binding site
WILSON, Douglas P, WAN, Zhao-Kui, BINNUN, Eva, ZHANG, Yan-Ling, TAM, May, ERBE, David V, TOBIN, James, XIN XU, LEUNG, Louis, SHILLING, Adam, TAM, Steve Y, MANSOUR, Tarek S, XU, Wei-Xin, LEE, Jinbo, KIRINCICH, Steven J, FOLLOWS, Bruce C, JOSEPH-MCCARTHY, Diane, FOREMAN, Kenneth, MORETTO, Alessandro, JUNJUN WU, MIN ZHU
Published in Journal of medicinal chemistry (2007)
Get full text
Published in Journal of medicinal chemistry (2007)
Journal Article
Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism
Dwyer, Jason M, Platt, Brian J, Rizzo, Stacey J Sukoff, Pulicicchio, Claudine M, Wantuch, Caitlin, Zhang, Mei-Yi, Cummons, Terri, Leventhal, Liza, Bender, Corey N, Zhang, Jean, Kowal, Dianne, Lu, Shendi, Rajarao, S Johannes R, Smith, Deborah L, Shilling, Adam D, Wang, Jianyao, Butera, John, Resnick, Lynn, Rosenzweig-Lipson, Sharon, Schechter, Lee E, Beyer, Chad E
Published in The international journal of neuropsychopharmacology (01.10.2010)
Published in The international journal of neuropsychopharmacology (01.10.2010)
Get full text
Journal Article