Hexanucleotide Repeats in ALS/FTD Form Length-Dependent RNA Foci, Sequester RNA Binding Proteins, and Are Neurotoxic
Lee, Youn-Bok, Chen, Han-Jou, Peres, João N., Gomez-Deza, Jorge, Attig, Jan, Štalekar, Maja, Troakes, Claire, Nishimura, Agnes L., Scotter, Emma L., Vance, Caroline, Adachi, Yoshitsugu, Sardone, Valentina, Miller, Jack W., Smith, Bradley N., Gallo, Jean-Marc, Ule, Jernej, Hirth, Frank, Rogelj, Boris, Houart, Corinne, Shaw, Christopher E.
Published in Cell reports (Cambridge) (01.12.2013)
Published in Cell reports (Cambridge) (01.12.2013)
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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
Lee, Youn-Bok, Baskaran, Pranetha, Gomez-Deza, Jorge, Chen, Han-Jou, Nishimura, Agnes L, Smith, Bradley N, Troakes, Claire, Adachi, Yoshitsugu, Stepto, Alan, Petrucelli, Leonard, Gallo, Jean-Marc, Hirth, Frank, Rogelj, Boris, Guthrie, Sarah, Shaw, Christopher E
Published in Human molecular genetics (15.12.2017)
Published in Human molecular genetics (15.12.2017)
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Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes
Diaper, Danielle C, Adachi, Yoshitsugu, Sutcliffe, Ben, Humphrey, Dickon M, Elliott, Christopher J H, Stepto, Alan, Ludlow, Zoe N, Vanden Broeck, Lies, Callaerts, Patrick, Dermaut, Bart, Al-Chalabi, Ammar, Shaw, Christopher E, Robinson, Iain M, Hirth, Frank
Published in Human molecular genetics (15.04.2013)
Published in Human molecular genetics (15.04.2013)
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A conserved nuclear receptor, Tailless, is required for efficient proliferation and prolonged maintenance of mushroom body progenitors in the Drosophila brain
Kurusu, Mitsuhiko, Maruyama, Yasushi, Adachi, Yoshitsugu, Okabe, Masataka, Suzuki, Emiko, Furukubo-Tokunaga, Katsuo
Published in Developmental biology (01.02.2009)
Published in Developmental biology (01.02.2009)
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TDP-43 Loss-of-Function Causes Neuronal Loss Due to Defective Steroid Receptor-Mediated Gene Program Switching in Drosophila
Vanden Broeck, Lies, Naval-Sánchez, Marina, Adachi, Yoshitsugu, Diaper, Danielle, Dourlen, Pierre, Chapuis, Julien, Kleinberger, Gernot, Gistelinck, Marc, Van Broeckhoven, Christine, Lambert, Jean-Charles, Hirth, Frank, Aerts, Stein, Callaerts, Patrick, Dermaut, Bart
Published in Cell reports (Cambridge) (31.01.2013)
Published in Cell reports (Cambridge) (31.01.2013)
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Journal Article
Cross-regulatory protein-protein interactions between Hox and Pax transcription factors
Plaza, Serge, Prince, Frederic, Adachi, Yoshitsugu, Punzo, Claudio, Cribbs, David L, Gehring, Walter J
Published in Proceedings of the National Academy of Sciences - PNAS (09.09.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (09.09.2008)
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Journal Article
A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration
Solomon, Daniel A, Stepto, Alan, Au, Wing Hei, Adachi, Yoshitsugu, Diaper, Danielle C, Hall, Rachel, Rekhi, Anjeet, Boudi, Adel, Tziortzouda, Paraskevi, Lee, Youn-Bok, Smith, Bradley, Bridi, Jessika C, Spinelli, Greta, Dearlove, Jonah, Humphrey, Dickon M, Gallo, Jean-Marc, Troakes, Claire, Fanto, Manolis, Soller, Matthias, Rogelj, Boris, Parsons, Richard B, Shaw, Christopher E, Hortobágyi, Tibor, Hirth, Frank
Published in Brain (London, England : 1878) (01.10.2018)
Published in Brain (London, England : 1878) (01.10.2018)
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Journal Article
C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity
Lee, Youn-Bok, Baskaran, Pranetha, Gomez-Deza, Jorge, Chen, Han-Jou, Nishimura, Agnes L, Smith, Bradley N, Troakes, Claire, Adachi, Yoshitsugu, Stepto, Alan, Petrucelli, Leonard, Gallo, Jean-Marc, Hirth, Frank, Rogelj, Boris, Guthrie, Sarah, Shaw, Christopher E
Published in Human molecular genetics (26.04.2021)
Published in Human molecular genetics (26.04.2021)
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Drosophila TDP-43 dysfunction in glia and muscle cells cause cytological and behavioural phenotypes that characterize ALS and FTLD
Diaper, Danielle C, Adachi, Yoshitsugu, Lazarou, Luke, Greenstein, Max, Simoes, Fabio A, Di Domenico, Angelique, Solomon, Daniel A, Lowe, Simon, Alsubaie, Rawan, Cheng, Daryl, Buckley, Stephen, Humphrey, Dickon M, Shaw, Christopher E, Hirth, Frank
Published in Human molecular genetics (01.10.2013)
Published in Human molecular genetics (01.10.2013)
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Journal Article
Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila
Papadopoulos, Dimitrios K., Skouloudaki, Kassiani, Adachi, Yoshitsugu, Samakovlis, Christos, Gehring, Walter J.
Published in Developmental biology (01.07.2012)
Published in Developmental biology (01.07.2012)
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Conserved cis-regulatory modules mediate complex neural expression patterns of the eyeless gene in the Drosophila brain
Adachi, Yoshitsugu, Hauck, Bernd, Clements, Jason, Kawauchi, Hiroshi, Kurusu, Mitsuhiko, Totani, Yoko, Kang, Yuan Yuan, Eggert, Tanja, Walldorf, Uwe, Furukubo-Tokunaga, Katsuo, Callaerts, Patrick
Published in Mechanisms of development (01.10.2003)
Published in Mechanisms of development (01.10.2003)
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Journal Article
P2‐134: TDP‐43 neurotoxicity is caused by a failure of steroid receptor–dependent transcriptional program switching in Drosophila
Dermaut, Bart, Broeck, Lies Vanden, Sanchez, Marina Naval, Adachi, Yoshitsugu, Diaper, Danielle, Kleinberger, Gernot, Gistelinck, Marc, Van Broeckhoven, Christine, Hirth, Frank, Aerts, Stein, Callaerts, Patrick
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
TDP-43 neurotoxicity is caused by a failure of steroid receptor–dependent transcriptional program switching in Drosophila
Dermaut, Bart, Broeck, Lies Vanden, Sanchez, Marina Naval, Adachi, Yoshitsugu, Diaper, Danielle, Kleinberger, Gernot, Gistelinck, Marc, Van Broeckhoven, Christine, Hirth, Frank, Aerts, Stein, Callaerts, Patrick
Published in Alzheimer's & dementia (01.07.2012)
Published in Alzheimer's & dementia (01.07.2012)
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Journal Article
Expanded G4C2 repeats linked to C9ORF72ALS and FTD form length-dependent RNA foci, sequester RNA binding proteins and are neurotoxic
Lee, Youn-Bok, Chen, Han-Jou, Peres, João N, Gomez, Jorge, Sardone, Valentina, Nishimura, Agnes L, Scotter, Emma, Vance, Caroline, Štalekar, Maja, Adachi, Yoshitsugu, Troakes, Claire, Miller, Jack, Smith, Bradley, Hirth, Frank, Rogelj, Boris, Houart, Corinne, Shaw, Christopher E
Published in Molecular neurodegeneration (13.09.2013)
Published in Molecular neurodegeneration (13.09.2013)
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Journal Article
Expanded G4C2 repeats linked to C9ORF72 ALS and FTD form length-dependent RNA foci, sequester RNA binding proteins and are neurotoxic
Lee, Youn-Bok, Chen, Han-Jou, Peres, João N, Gomez, Jorge, Sardone, Valentina, Nishimura, Agnes L, Scotter, Emma, Vance, Caroline, Stalekar, Maja, Adachi, Yoshitsugu, Troakes, Claire, Miller, Jack, Smith, Bradley, Hirth, Frank, Rogelj, Boris, Houart, Corinne, Shaw, Christopher E
Published in Molecular neurodegeneration (13.09.2013)
Published in Molecular neurodegeneration (13.09.2013)
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Journal Article
Radiation Shielding of a Cyclotron for PET
KUROSAWA, Tadahiro, NAKAMURA, Takashi, KIM, Eunju, TAKADA, Masashi, HAYASHI, Yoshihiro, MORITA, Takuzo, ADACHI, Yoshitsugu
Published in RADIOISOTOPES (15.11.1996)
Published in RADIOISOTOPES (15.11.1996)
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