Specific Substitutions in the Echinocandin Target Fks1p Account for Reduced Susceptibility of Rare Laboratory and Clinical Candida sp. Isolates
PARK, S, KELLY, R, FLATTERY, A, GILL, C, CHREBET, G, PARENT, S. A, KURTZ, M, TEPPLER, H, DOUGLAS, C. M, PERLIN, D. S, KAHN, J. Nielsen, ROBLES, J, HSU, M.-J, REGISTER, E, LI, W, VYAS, V, FAN, H, ABRUZZO, G
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Published in Antimicrobial Agents and Chemotherapy (01.08.2005)
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Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: Demonstration of efficacy of caspofungin acetate
BOWMAN, J. C, ABRUZZO, G. K, ANDERSON, J. W, FLATTERY, A. M, GILL, C. J, PIKOUNIS, V. B, SCHMATZ, D. M, LIBERATOR, P. A, DOUGLAS, C. M
Published in Antimicrobial agents and chemotherapy (01.12.2001)
Published in Antimicrobial agents and chemotherapy (01.12.2001)
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Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors
DOUGLAS, C. M, D'IPPOLITO, J. A, MITCHELL, A, KURTZ, M. B, SHEI, G. J, MEINZ, M, ONISHI, J, MARRINAN, J. A, LI, W, ABRUZZO, G. K, FLATTERY, A, BARTIZAL, K
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
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Discovery of Novel Antifungal (1,3)-β-d-Glucan Synthase Inhibitors
ONISHI, J, MEINZ, M, CABELLO, A, VICENTE, F, PELAEZ, F, DIEZ, M. T, MARTIN, I, BILLS, G, GIACOBBE, R, DOMBROWSKI, A, SCHWARTZ, R, MORRIS, S, THOMPSON, J, HARRIS, G, TSIPOURAS, A, WILSON, K, KURTZ, M. B, CUROTTO, J, DREIKORN, S, ROSENBACH, M, DOUGLAS, C, ABRUZZO, G, FLATTERY, A, KONG, L
Published in Antimicrobial Agents and Chemotherapy (01.02.2000)
Published in Antimicrobial Agents and Chemotherapy (01.02.2000)
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Efficacy of the Echinocandin Caspofungin against Disseminated Aspergillosis and Candidiasis in Cyclophosphamide-Induced Immunosuppressed Mice
ABRUZZO, G. K, GILL, C. J, FLATTERY, A. M, KONG, L, LEIGHTON, C, SMITH, J. G, PIKOUNIS, V. B, BARTIZAL, K, ROSEN, H
Published in Antimicrobial Agents and Chemotherapy (01.09.2000)
Published in Antimicrobial Agents and Chemotherapy (01.09.2000)
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In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872)
BARTIZAL, K, GILL, C. J, BALKOVEC, J, ABRUZZO, G. K, FLATTERY, A. M, KONG, L, SCOTT, P. M, SMITH, J. G, LEIGHTON, C. E, BOUFFARD, A, DROPINSKI, J. F
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
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Efficacy of Caspofungin against Aspergillus flavus, Aspergillus terreus, and Aspergillus nidulans
BOWMAN, J. C, ABRUZZO, G. K, WANG, T. C, DOUGLAS, C. M, FLATTERY, A. M, GILL, C. J, HICKEY, E. J, HSU, M. J, NIELSEN KAHN, J, LIBERATOR, P. A, MISURA, A. S, PELAK, B. A
Published in Antimicrobial Agents and Chemotherapy (01.12.2006)
Published in Antimicrobial Agents and Chemotherapy (01.12.2006)
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Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis
ABRUZZO, G. K, FLATTERY, A. M, KROPP, H, BARTIZAL, K, GILL, C. J, KONG, L, SMITH, J. G, PIKOUNIS, V. B, BALKOVEC, J. M, BOUFFARD, A. F, DROPINSKI, J. F, ROSEN, H
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
Published in Antimicrobial Agents and Chemotherapy (01.11.1997)
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Characterization of echinocandin-resistant mutants of Candida albicans: genetic, biochemical, and virulence studies
KURTZ, M. B, ABRUZZO, G, FLATTERY, A, BARTIZAL, K, MARRINAN, J. A, LI, W, MILLIGAN, J, NOLLSTADT, K, DOUGLAS, C. M
Published in Infection and Immunity (01.08.1996)
Published in Infection and Immunity (01.08.1996)
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Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis
Abruzzo, G K, Flattery, A M, Gill, C J, Kong, L, Smith, J G, Krupa, D, Pikounis, V B, Kropp, H, Bartizal, K
Published in Antimicrobial Agents and Chemotherapy (01.05.1995)
Published in Antimicrobial Agents and Chemotherapy (01.05.1995)
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Inactivation of Kex2p Diminishes the Virulence of Candida albicans
Newport, George, Kuo, Alan, Flattery, Amy, Gill, Charles, Blake, Julie J., Kurtz, Myra B., Abruzzo, George K., Agabian, Nina
Published in The Journal of biological chemistry (17.01.2003)
Published in The Journal of biological chemistry (17.01.2003)
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Antimicrobial activity of ergokonin A from Trichoderma longibrachiatum
Vicente, M.F., Cabello, A., Platas, G., Basilio, A., Díez, M.T., Dreikorn, S., Giacobbe, R.A., Onishi, J.C., Meinz, M., Kurtz, M.B., Rosenbach, M., Thompson, J., Abruzzo, G., Flattery, A., Kong, L., Tsipouras, A., Wilson, K.E., Peláez, F.
Published in Journal of applied microbiology (01.11.2001)
Published in Journal of applied microbiology (01.11.2001)
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In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin
BARTIZAL, K, ABRUZZO, G, TRAINOR, C, KRUPA, D, NOLLSTADT, K, SCHMATZ, D, SCHWARTZ, R, HAMMOND, M, BALKOVEC, J, VANMIDDLESWORTH, F
Published in Antimicrobial Agents and Chemotherapy (01.08.1992)
Published in Antimicrobial Agents and Chemotherapy (01.08.1992)
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The Discovery of Enfumafungin, a Novel Antifungal Compound Produced by an Endophytic Hormonema Species Biological Activity and Taxonomy of the Producing Organisms
Peláez, Fernando, Cabello, Angeles, Platas, Gonzalo, Díez, María T., del Val, Antonio González, Basilio, Angela, Martán, Isabel, Vicente, Francisca, Bills, Gerald F., Giacobbe, Robert A, Schwartz, Robert E., Onishi, Janet C., Meinz, Maria S., Abruzzo, George K., Flattery, Amy M., Kong, Li, Kurtz, Myra B.
Published in Systematic and applied microbiology (01.10.2000)
Published in Systematic and applied microbiology (01.10.2000)
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Rustmicin, a Potent Antifungal Agent, Inhibits Sphingolipid Synthesis at Inositol Phosphoceramide Synthase
Mandala, Suzanne M., Thornton, Rosemary A., Milligan, James, Rosenbach, Mark, Garcia-Calvo, Margarita, Bull, Herbert G., Harris, Guy, Abruzzo, George K., Flattery, Amy M., Gill, Charles J., Bartizal, Kenneth, Dreikorn, Sarah, Kurtz, Myra B.
Published in The Journal of biological chemistry (12.06.1998)
Published in The Journal of biological chemistry (12.06.1998)
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Antibacterial Activity of Lonchocarpol A
Salvatore, Michael J, King, Aurora B, Graham, Amy C, Onishi, H. Russell, Bartizal, Kenneth F, Abruzzo, George K, Gill, Charles J, Ramjit, Harri G, Pitzenberger, Steven M, Witherup, Keith M
Published in Journal of natural products (Washington, D.C.) (01.05.1998)
Published in Journal of natural products (Washington, D.C.) (01.05.1998)
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Increased antifungal activity of L-733,560, a water-soluble, semisynthetic pneumocandin, is due to enhanced inhibition of cell wall synthesis
KURTZ, M. B, DOUGLAS, C, BOUFFARD, F. A, DROPINSKI, J. F, HAMMOND, M. L, ZAMBIAS, R. A, ABRUZZO, G, BARTIZAL, K, MCMANUS, O. B, GARCIA, M. L, MARRINAN, J, NOLLSTADT, K, ONISHI, J, DREIKORN, S, MILLIGAN, J, MANDALA, S, THOMPSON, J, BALKOVEC, J. M
Published in Antimicrobial Agents and Chemotherapy (01.12.1994)
Published in Antimicrobial Agents and Chemotherapy (01.12.1994)
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New model of oropharyngeal and gastrointestinal colonization by Candida albicans in CD4+ T-cell-deficient mice for evaluation of antifungal agents
FLATTERY, A. M, ABRUZZO, G. K, GILL, C. J, SMITH, J. G, BARTIZAL, K
Published in Antimicrobial Agents and Chemotherapy (01.07.1996)
Published in Antimicrobial Agents and Chemotherapy (01.07.1996)
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Dissociation of Mitogenesis and Late-Stage Promotion of Tumor Cell Phenotype by Phorbol Esters: Mitogen-Resistant Variants are Sensitive to Promotion
Colburn, Nancy H., Wendel, Edmund J., Abruzzo, Gina
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1981)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1981)
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