Functional rescue of an ABCB11 mutant by ivacaftor: A new targeted pharmacotherapy approach in bile salt export pump deficiency
Mareux, Elodie, Lapalus, Martine, Amzal, Rachida, Almes, Marion, Aït‐Slimane, Tounsia, Delaunay, Jean‐Louis, Adnot, Pauline, Collado‐Hilly, Mauricette, Davit‐Spraul, Anne, Falguières, Thomas, Callebaut, Isabelle, Gonzales, Emmanuel, Jacquemin, Emmanuel
Published in Liver international (01.08.2020)
Published in Liver international (01.08.2020)
Get full text
Journal Article
Inhibition of receptor-interacting protein kinase 1 improves experimental non-alcoholic fatty liver disease
Majdi, Amine, Aoudjehane, Lynda, Ratziu, Vlad, Islam, Tawhidul, Afonso, Marta B., Conti, Filomena, Mestiri, Taïeb, Lagouge, Marie, Foufelle, Fabienne, Ballenghien, Florine, Ledent, Tatiana, Moldes, Marthe, Cadoret, Axelle, Fouassier, Laura, Delaunay, Jean-Louis, Aït-Slimane, Tounsia, Courtois, Gilles, Fève, Bruno, Scatton, Olivier, Prip-Buus, Carina, Rodrigues, Cecília M.P., Housset, Chantal, Gautheron, Jérémie
Published in Journal of hepatology (01.04.2020)
Published in Journal of hepatology (01.04.2020)
Get full text
Journal Article
A functional classification of ABCB4 variations causing progressive familial intrahepatic cholestasis type 3
Delaunay, Jean‐Louis, Durand‐Schneider, Anne‐Marie, Dossier, Claire, Falguières, Thomas, Gautherot, Julien, Davit‐Spraul, Anne, Aït‐Slimane, Tounsia, Housset, Chantal, Jacquemin, Emmanuel, Maurice, Michèle
Published in Hepatology (Baltimore, Md.) (01.05.2016)
Published in Hepatology (Baltimore, Md.) (01.05.2016)
Get full text
Journal Article
Functional defect of variants in the adenosine triphosphate–binding sites of ABCB4 and their rescue by the cystic fibrosis transmembrane conductance regulator potentiator, ivacaftor (VX‐770)
Delaunay, Jean‐Louis, Bruneau, Alix, Hoffmann, Brice, Durand‐Schneider, Anne‐Marie, Barbu, Véronique, Jacquemin, Emmanuel, Maurice, Michèle, Housset, Chantal, Callebaut, Isabelle, Aït‐Slimane, Tounsia
Published in Hepatology (Baltimore, Md.) (01.02.2017)
Published in Hepatology (Baltimore, Md.) (01.02.2017)
Get full text
Journal Article
Effect of CFTR correctors on the traffic and the function of intracellularly retained ABCB4 variants
Ben Saad, Amel, Vauthier, Virginie, Tóth, Ágota, Janaszkiewicz, Angelika, Durand‐Schneider, Anne‐Marie, Bruneau, Alix, Delaunay, Jean‐Louis, Lapalus, Martine, Mareux, Elodie, Garcin, Isabelle, Gonzales, Emmanuel, Housset, Chantal, Aït‐Slimane, Tounsia, Jacquemin, Emmanuel, Di Meo, Florent, Falguières, Thomas
Published in Liver international (01.06.2021)
Published in Liver international (01.06.2021)
Get full text
Journal Article
Molecular Regulation of Canalicular ABC Transporters
Ben Saad, Amel, Bruneau, Alix, Mareux, Elodie, Lapalus, Martine, Delaunay, Jean-Louis, Gonzales, Emmanuel, Jacquemin, Emmanuel, Aït-Slimane, Tounsia, Falguières, Thomas
Published in International journal of molecular sciences (20.02.2021)
Published in International journal of molecular sciences (20.02.2021)
Get full text
Journal Article
Ivacaftor-Mediated Potentiation of ABCB4 Missense Mutations Affecting Critical Motifs of the NBDs: Repositioning Perspectives for Hepatobiliary Diseases
Delaunay, Jean-Louis, Elbahnsi, Ahmad, Bruneau, Alix, Madry, Claire, Durand-Schneider, Anne-Marie, Stary, Anne, Housset, Chantal, Gautheron, Jérémie, Callebaut, Isabelle, Aït-Slimane, Tounsia
Published in International journal of molecular sciences (08.01.2023)
Published in International journal of molecular sciences (08.01.2023)
Get full text
Journal Article
RAB10 Interacts with ABCB4 and Regulates Its Intracellular Traffic
Ben Saad, Amel, Vauthier, Virginie, Lapalus, Martine, Mareux, Elodie, Bennana, Evangéline, Durand-Schneider, Anne-Marie, Bruneau, Alix, Delaunay, Jean-Louis, Gonzales, Emmanuel, Housset, Chantal, Aït-Slimane, Tounsia, Guillonneau, François, Jacquemin, Emmanuel, Falguières, Thomas
Published in International journal of molecular sciences (30.06.2021)
Published in International journal of molecular sciences (30.06.2021)
Get full text
Journal Article
Basolateral internalization of GPI-anchored proteins occurs via a clathrin-independent flotillin-dependent pathway in polarized hepatic cells
Aït-Slimane, Tounsia, Galmes, Romain, Trugnan, Germain, Maurice, Michèle
Published in Molecular biology of the cell (01.09.2009)
Published in Molecular biology of the cell (01.09.2009)
Get full text
Journal Article
Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models
Vauthier, Virginie, Ben Saad, Amel, Elie, Jonathan, Oumata, Nassima, Durand-Schneider, Anne-Marie, Bruneau, Alix, Delaunay, Jean-Louis, Housset, Chantal, Aït-Slimane, Tounsia, Meijer, Laurent, Falguières, Thomas
Published in Scientific reports (30.04.2019)
Published in Scientific reports (30.04.2019)
Get full text
Journal Article
Phosphorylation of ABCB4 impacts its function: Insights from disease‐causing mutations
Gautherot, Julien, Delautier, Danièle, Maubert, Marie‐Anne, Aït‐Slimane, Tounsia, Bolbach, Gérard, Delaunay, Jean‐Louis, Durand‐Schneider, Anne‐Marie, Firrincieli, Delphine, Barbu, Véronique, Chignard, Nicolas, Housset, Chantal, Maurice, Michèle, Falguières, Thomas
Published in Hepatology (Baltimore, Md.) (01.08.2014)
Published in Hepatology (Baltimore, Md.) (01.08.2014)
Get full text
Journal Article
A PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression
Venot, Quitterie, Delaunay, Jean-Louis, Fouassier, Laura, Delautier, Danièle, Falguières, Thomas, Housset, Chantal, Maurice, Michèle, Aït-Slimane, Tounsia
Published in PloS one (20.01.2016)
Published in PloS one (20.01.2016)
Get full text
Journal Article
The necroptosis-inducing pseudokinase mixed lineage kinase domain-like regulates the adipogenic differentiation of pre-adipocytes
Magusto, Julie, Beaupère, Carine, Afonso, Marta B., Auclair, Martine, Delaunay, Jean-Louis, Soret, Pierre-Antoine, Courtois, Gilles, Aït-Slimane, Tounsia, Housset, Chantal, Jéru, Isabelle, Fève, Bruno, Ratziu, Vlad, Rodrigues, Cecilia M.P., Gautheron, Jérémie
Published in iScience (21.10.2022)
Published in iScience (21.10.2022)
Get full text
Journal Article
MRCK-Alpha and Its Effector Myosin II Regulatory Light Chain Bind ABCB4 and Regulate Its Membrane Expression
Bruneau, Alix, Delaunay, Jean-Louis, Durand-Schneider, Anne-Marie, Vauthier, Virginie, Ben Saad, Amel, Aoudjehane, Lynda, El Mourabit, Haquima, Morichon, Romain, Falguières, Thomas, Gautheron, Jérémie, Housset, Chantal, Aït-Slimane, Tounsia
Published in Cells (Basel, Switzerland) (10.02.2022)
Published in Cells (Basel, Switzerland) (10.02.2022)
Get full text
Journal Article
A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature
Delaunay, Jean‐Louis, Durand‐Schneider, Anne‐Marie, Delautier, Danièle, Rada, Alegna, Gautherot, Julien, Jacquemin, Emmanuel, Aït‐Slimane, Tounsia, Maurice, Michèle
Published in Hepatology (Baltimore, Md.) (01.04.2009)
Published in Hepatology (Baltimore, Md.) (01.04.2009)
Get full text
Journal Article
ADH1B, the adipocyte-enriched alcohol dehydrogenase, plays an essential, cell-autonomous role in human adipogenesis
Gautheron, Jérémie, Elsayed, Solaf, Pistorio, Valeria, Lockhart, Sam, Zammouri, Jamila, Auclair, Martine, Koulman, Albert, Meadows, Sarah R, Lhomme, Marie, Ponnaiah, Maharajah, Si-Bouazza, Redouane, Fabrega, Sylvie, Belkadi, Abdelaziz, Delaunay, Jean-Louis, Aït-Slimane, Tounsia, Fève, Bruno, Vigouroux, Corinne, Abdel Ghaffar, Tawhida Y, O'Rahilly, Stephen, Jéru, Isabelle
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2024)
Get full text
Journal Article
Comparison of in silico prediction and experimental assessment of ABCB4 variants identified in patients with biliary diseases
Khabou, Boudour, Durand-Schneider, Anne-Marie, Delaunay, Jean-Louis, Aït-Slimane, Tounsia, Barbu, Véronique, Fakhfakh, Faiza, Housset, Chantal, Maurice, Michèle
Published in The international journal of biochemistry & cell biology (01.08.2017)
Published in The international journal of biochemistry & cell biology (01.08.2017)
Get full text
Journal Article
Effects of Cellular, Chemical, and Pharmacological Chaperones on the Rescue of a Trafficking-defective Mutant of the ATP-binding Cassette Transporter Proteins ABCB1/ABCB4
Gautherot, Julien, Durand-Schneider, Anne-Marie, Delautier, Danièle, Delaunay, Jean-Louis, Rada, Alegna, Gabillet, Julie, Housset, Chantal, Maurice, Michèle, Aït-Slimane, Tounsia
Published in The Journal of biological chemistry (10.02.2012)
Published in The Journal of biological chemistry (10.02.2012)
Get full text
Journal Article
ABCB4: Insights from pathobiology into therapy
Falguières, Thomas, Aït-Slimane, Tounsia, Housset, Chantal, Maurice, Michèle
Published in Clinics and research in hepatology and gastroenterology (01.10.2014)
Published in Clinics and research in hepatology and gastroenterology (01.10.2014)
Get full text
Journal Article