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Pharmacokinetic and pharmacodynamic actions of clozapine-N-oxide, clozapine, and compound 21 in DREADD-based chemogenetics in mice
Jendryka, Martin, Palchaudhuri, Monika, Ursu, Daniel, van der Veen, Bastiaan, Liss, Birgit, Kätzel, Dennis, Nissen, Wiebke, Pekcec, Anton
Published in Scientific reports (14.03.2019)
Published in Scientific reports (14.03.2019)
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Accumulation of succinate controls activation of adipose tissue thermogenesis
Mills, Evanna L., Pierce, Kerry A., Jedrychowski, Mark P., Garrity, Ryan, Winther, Sally, Vidoni, Sara, Yoneshiro, Takeshi, Spinelli, Jessica B., Lu, Gina Z., Kazak, Lawrence, Banks, Alexander S., Haigis, Marcia C., Kajimura, Shingo, Murphy, Michael P., Gygi, Steven P., Clish, Clary B., Chouchani, Edward T.
Published in Nature (London) (01.08.2018)
Published in Nature (London) (01.08.2018)
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Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice
Andres-Hernando, Ana, Li, Nanxing, Cicerchi, Christina, Inaba, Shinichiro, Chen, Wei, Roncal-Jimenez, Carlos, Le, Myphuong T., Wempe, Michael F., Milagres, Tamara, Ishimoto, Takuji, Fini, Mehdi, Nakagawa, Takahiko, Johnson, Richard J., Lanaspa, Miguel A.
Published in Nature communications (13.02.2017)
Published in Nature communications (13.02.2017)
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A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after traumatic brain injury
Du, Mengran, Wu, Chenrui, Yu, Renqiang, Cheng, Yuqi, Tang, Zhaohua, Wu, Biying, Fu, Jiayuanyuan, Tan, Weilin, Zhou, Qiang, Zhu, Ziyu, Balawi, Ehab, Huang, Xuekang, Ma, Jun, Liao, Z. B.
Published in Molecular psychiatry (01.11.2022)
Published in Molecular psychiatry (01.11.2022)
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Genomic profiling of Sézary syndrome identifies alterations of key T cell signaling and differentiation genes
Wang, Linghua, Ni, Xiao, Covington, Kyle R, Yang, Betty Y, Shiu, Jessica, Zhang, Xiang, Xi, Liu, Meng, Qingchang, Langridge, Timothy, Drummond, Jennifer, Donehower, Lawrence A, Doddapaneni, Harshavardhan, Muzny, Donna M, Gibbs, Richard A, Wheeler, David A, Duvic, Madeleine
Published in Nature genetics (01.12.2015)
Published in Nature genetics (01.12.2015)
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Effect of protocatechuic acid on insulin responsiveness and inflammation in visceral adipose tissue from obese individuals: possible role for PTP1B
Ormazabal, Paulina, Scazzocchio, Beatrice, Varì, Rosaria, Santangelo, Carmela, D’Archivio, Massimo, Silecchia, Gianfranco, Iacovelli, Annunziata, Giovannini, Claudio, Masella, Roberta
Published in International Journal of Obesity (01.12.2018)
Published in International Journal of Obesity (01.12.2018)
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Regulation of sarcomagenesis by the empty spiracles homeobox genes EMX1 and EMX2
Amancio Carnero, Manuel P. Jiménez-García, Daniel Otero-Albiol, Antonio Lucena-Cacace
Published in Cell Death & Disease (20.05.2021)
Published in Cell Death & Disease (20.05.2021)
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A human neurodevelopmental model for Williams syndrome
Chailangkarn, Thanathom, Trujillo, Cleber A., Freitas, Beatriz C., Hrvoj-Mihic, Branka, Herai, Roberto H., Yu, Diana X., Brown, Timothy T., Marchetto, Maria C., Bardy, Cedric, McHenry, Lauren, Stefanacci, Lisa, Järvinen, Anna, Searcy, Yvonne M., DeWitt, Michelle, Wong, Wenny, Lai, Philip, Ard, M. Colin, Hanson, Kari L., Romero, Sarah, Jacobs, Bob, Dale, Anders M., Dai, Li, Korenberg, Julie R., Gage, Fred H., Bellugi, Ursula, Halgren, Eric, Semendeferi, Katerina, Muotri, Alysson R.
Published in Nature (London) (18.08.2016)
Published in Nature (London) (18.08.2016)
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Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c
Edelstein, Leonard C, Simon, Lukas M, Montoya, Raúl Teruel, Holinstat, Michael, Chen, Edward S, Bergeron, Angela, Kong, Xianguo, Nagalla, Srikanth, Mohandas, Narla, Cohen, David E, Dong, Jing-fei, Shaw, Chad, Bray, Paul F
Published in Nature medicine (01.12.2013)
Published in Nature medicine (01.12.2013)
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Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor
Guo, Xuanming, Asthana, Pallavi, Gurung, Susma, Zhang, Shuo, Wong, Sheung Kin Ken, Fallah, Samane, Chow, Chi Fung Willis, Che, Sijia, Zhai, Lixiang, Wang, Zening, Ge, Xin, Jiang, Zhixin, Wu, Jiayan, Zhang, Yijing, Wu, Xiaoyu, Xu, Keyang, Lin, Cheng Yuan, Kwan, Hiu Yee, Lyu, Aiping, Zhou, Zhongjun, Bian, Zhao-Xiang, Wong, Hoi Leong Xavier
Published in Nature communications (29.06.2022)
Published in Nature communications (29.06.2022)
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A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability
Liu, Jiang, Wang, Ying, Song, Lizhi, Zeng, Linghua, Yi, Weiwei, Liu, Ting, Chen, Huanzhen, Wang, Miao, Ju, Zhenyu, Cong, Yu-Sheng
Published in Nature communications (27.01.2017)
Published in Nature communications (27.01.2017)
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Skin α-synuclein deposits differ in clinical variants of synucleinopathy: an in vivo study
Donadio, V., Incensi, A., El-Agnaf, O., Rizzo, G., Vaikath, N., Del Sorbo, F., Scaglione, C., Capellari, S., Elia, A., Stanzani Maserati, M., Pantieri, R., Liguori, R.
Published in Scientific reports (24.09.2018)
Published in Scientific reports (24.09.2018)
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HITM-SIR: phase Ib trial of intraarterial chimeric antigen receptor T-cell therapy and selective internal radiation therapy for CEA+ liver metastases
Katz, Steven C., Hardaway, John, Prince, Ethan, Guha, Prajna, Cunetta, Marissa, Moody, Ashley, Wang, Li Juan, Armenio, Vincent, Espat, N. Joseph, Junghans, Richard P.
Published in Cancer gene therapy (01.05.2020)
Published in Cancer gene therapy (01.05.2020)
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CDX2 downregulation regulates intrinsic WNT pathway activation, dictating metastasis in APC and CTNNB1 wildtype colorectal cancer
Wouters, Valérie M., Helderman, Roxan F. C. P. A., Cameron, Kate, van der Hooff, Sander R., Torang, Arezo, van den Bergh, Saskia, Jackstadt, Rene, Sansom, Owen J., van Neerven, Sanne M., Medema, Jan Paul
Published in Oncogene (07.07.2025)
Published in Oncogene (07.07.2025)
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Spliceosome component Usp39 contributes to hepatic lipid homeostasis through the regulation of autophagy
Cui, Donghai, Wang, Zixiang, Dang, Qianli, Wang, Jing, Qin, Junchao, Song, Jianping, Zhai, Xiangyu, Zhou, Yachao, Zhao, Ling, Lu, Gang, Liu, Hongbin, Liu, Gang, Liu, Runping, Shao, Changshun, Zhang, Xiyu, Liu, Zhaojian
Published in Nature communications (03.11.2023)
Published in Nature communications (03.11.2023)
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3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer’s disease
Lomoio, Selene, Pandey, Ravi S., Rouleau, Nicolas, Menicacci, Beatrice, Kim, WonHee, Cantley, William L., Haydon, Philip G., Bennett, David A., Young-Pearse, Tracy L., Carter, Gregory W., Kaplan, David L., Tesco, Giuseppina
Published in Molecular psychiatry (01.12.2023)
Published in Molecular psychiatry (01.12.2023)
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Upregulation of angiostatic chemokines IP-10/CXCL10 and I-TAC/CXCL11 in human obesity and their implication for adipose tissue angiogenesis
Hueso, Luisa, Ortega, Rebeca, Selles, Francisca, Wu-Xiong, Ning Yun, Ortega, Joaquin, Civera, Miguel, Ascaso, Juan F, Sanz, Maria-Jesus, Real, José T, Piqueras, Laura
Published in International Journal of Obesity (01.08.2018)
Published in International Journal of Obesity (01.08.2018)
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