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Somatic mutations precede acute myeloid leukemia years before diagnosis
Desai, Pinkal, Mencia-Trinchant, Nuria, Savenkov, Oleksandr, Simon, Michael S, Cheang, Gloria, Lee, Sangmin, Samuel, Michael, Ritchie, Ellen K, Guzman, Monica L, Ballman, Karla V, Roboz, Gail J, Hassane, Duane C
Published in Nature medicine (01.07.2018)
Published in Nature medicine (01.07.2018)
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The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
Bolouri, Hamid, Farrar, Jason E, Triche, Jr, Timothy, Ries, Rhonda E, Lim, Emilia L, Alonzo, Todd A, Ma, Yussanne, Moore, Richard, Mungall, Andrew J, Marra, Marco A, Zhang, Jinghui, Ma, Xiaotu, Liu, Yu, Liu, Yanling, Guidry Auvil, Jaime M, Davidsen, Tanja M, Gesuwan, Patee, Hermida, Leandro C, Salhia, Bodour, Capone, Stephen, Ramsingh, Giridharan, Zwaan, Christian Michel, Noort, Sanne, Piccolo, Stephen R, Kolb, E Anders, Gamis, Alan S, Smith, Malcolm A, Gerhard, Daniela S, Meshinchi, Soheil
Published in Nature medicine (01.01.2018)
Published in Nature medicine (01.01.2018)
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Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells
Tremblay, Cedric S., Chiu, Sung Kai, Saw, Jesslyn, McCalmont, Hannah, Litalien, Veronique, Boyle, Jacqueline, Sonderegger, Stefan E., Chau, Ngoc, Evans, Kathryn, Cerruti, Loretta, Salmon, Jessica M., McCluskey, Adam, Lock, Richard B., Robinson, Phillip J., Jane, Stephen M., Curtis, David J.
Published in Nature communications (04.12.2020)
Published in Nature communications (04.12.2020)
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Histidine catabolism is a major determinant of methotrexate sensitivity
Kanarek, Naama, Keys, Heather R., Cantor, Jason R., Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Freinkman, Elizaveta, Schweitzer, Lawrence D., Sabatini, David M.
Published in Nature (London) (01.07.2018)
Published in Nature (London) (01.07.2018)
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Cytokine-mediated CAR T therapy resistance in AML
Bhagwat, Anand S., Torres, Leonel, Shestova, Olga, Shestov, Maksim, Mellors, Patrick W., Fisher, Han R., Farooki, Saamia N., Frost, Benjamin F., Loken, Michael R., Gaymon, Avery L., Frazee, Diane, Rogal, Walter, Frey, Noelle, Hexner, Elizabeth O., Luger, Selina M., Loren, Alison W., Martin, Mary Ellen, McCurdy, Shannon R., Perl, Alexander E., Stadtmauer, Edward A., Brogdon, Jennifer L., Fraietta, Joseph A., Hwang, Wei-Ting, Siegel, Don L., Plesa, Gabriela, Aplenc, Richard, Porter, David L., June, Carl H., Gill, Saar I.
Published in Nature medicine (01.12.2024)
Published in Nature medicine (01.12.2024)
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miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia
Jiang, Xi, Hu, Chao, Arnovitz, Stephen, Bugno, Jason, Yu, Miao, Zuo, Zhixiang, Chen, Ping, Huang, Hao, Ulrich, Bryan, Gurbuxani, Sandeep, Weng, Hengyou, Strong, Jennifer, Wang, Yungui, Li, Yuanyuan, Salat, Justin, Li, Shenglai, Elkahloun, Abdel G., Yang, Yang, Neilly, Mary Beth, Larson, Richard A., Le Beau, Michelle M., Herold, Tobias, Bohlander, Stefan K., Liu, Paul P., Zhang, Jiwang, Li, Zejuan, He, Chuan, Jin, Jie, Hong, Seungpyo, Chen, Jianjun
Published in Nature communications (26.04.2016)
Published in Nature communications (26.04.2016)
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Is the Sokal or EUTOS long-term survival (ELTS) score a better predictor of responses and outcomes in persons with chronic myeloid leukemia receiving tyrosine-kinase inhibitors?
Zhang, Xiao-Shuai, Gale, Robert Peter, Huang, Xiao-Jun, Jiang, Qian
Published in Leukemia (01.02.2022)
Published in Leukemia (01.02.2022)
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Ibrutinib inhibits collagen-mediated but not ADP-mediated platelet aggregation
Kamel, S, Horton, L, Ysebaert, L, Levade, M, Burbury, K, Tan, S, Cole-Sinclair, M, Reynolds, J, Filshie, R, Schischka, S, Khot, A, Sandhu, S, Keating, M J, Nandurkar, H, Tam, C S
Published in Leukemia (01.04.2015)
Published in Leukemia (01.04.2015)
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Donor and recipient age, gender and ABO incompatibility regardless of donor source: validated criteria for donor selection for haematopoietic transplants
Wang, Y, Wu, D-P, Liu, Q-F, Xu, L-P, Liu, K-Y, Zhang, X-H, Xu, Y, Huang, F, Huang, X-J
Published in Leukemia (01.02.2018)
Published in Leukemia (01.02.2018)
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Predictive scoring systems for molecular responses in persons with chronic phase chronic myeloid leukemia receiving initial imatinib therapy
Zhang, Xiao-shuai, Gale, Robert Peter, Li, Zi-yu, Zhang, Meng-yu, Huang, Xiao-jun, Jiang, Qian
Published in Leukemia (01.08.2022)
Published in Leukemia (01.08.2022)
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Co-variates associated with outcomes of tyrosine kinase-inhibitor therapy in persons with chronic myeloid leukaemia initially presenting in accelerated phase
Yang, Sen, Zhang, Xiao-shuai, Gale, Robert Peter, Huang, Xiao-jun, Jiang, Qian
Published in Leukemia (01.07.2022)
Published in Leukemia (01.07.2022)
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Targeting the NTSR2/TrkB oncogenic pathway in chronic lymphocytic leukemia
Ikhlef, Léa, Yassine, May, Chandouri, Boutaîna, Rivière, Léa, Naves, Thomas, Dmytruk, Natalya, Gachard, Nathalie, Jauberteau, Marie-Odile, Gallet, Paul-François
Published in Scientific reports (13.03.2024)
Published in Scientific reports (13.03.2024)
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Clinical outcomes of a new local CD19 CAR-T cell therapy for patients with relapsed or refractory acute lymphoblastic leukemia and non-Hodgkin lymphoma in Malaysia
Abdul Wahid, S. Fadilah, Ismail, Nor Azimah, Md Fauzi, Muhammad Firdaus, Mohd Idris, Mohd Razif, Yusop, Mohd Syahrir, Lim, Timothy, Muhamad, Nor Asiah
Published in Bone marrow transplantation (Basingstoke) (01.08.2025)
Published in Bone marrow transplantation (Basingstoke) (01.08.2025)
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DNA methylation at birth in monozygotic twins discordant for pediatric acute lymphoblastic leukemia
Nickels, Eric M., Li, Shaobo, Myint, Swe Swe, Arroyo, Katti, Feng, Qianxi, Siegmund, Kimberly D., de Smith, Adam J., Wiemels, Joseph L.
Published in Nature communications (14.10.2022)
Published in Nature communications (14.10.2022)
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MLL oncoprotein levels influence leukemia lineage identities
Janssens, Derek H., Duran, Melodie, Otto, Dominik J., Wu, Weifang, Xu, Yiling, Kirkey, Danielle, Mullighan, Charles G., Yi, Joanna S., Meshinchi, Soheil, Sarthy, Jay F., Ahmad, Kami, Henikoff, Steven
Published in Nature communications (29.10.2024)
Published in Nature communications (29.10.2024)
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European experience and risk factor analysis of donor cell-derived leukaemias/MDS following haematopoietic cell transplantation
Engel, Nicole, Rovo, Alicia, Badoglio, Manuela, Labopin, Myriam, Basak, Grzegorz W., Beguin, Yves, Guyotat, Denis, Ljungman, Per, Nagler, Arnon, Schattenberg, Anton, Schroeder, Thomas, Schroyens, Wilfried, Tischer, Johanna, Socie, Gerard, Kolb, Hans-Jochem, Tichelli, Andre, Salooja, Nina, Duarte, Rafael F.
Published in Leukemia (01.02.2019)
Published in Leukemia (01.02.2019)
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Effect of pediatric- versus adult-type chemotherapy regimens on outcomes of allogeneic hematopoietic stem cell transplants for adult T-cell acute lymphoblastic leukemia in first complete remission
Qi, Han-zhou, Xu, Jun, Yang, Qian-qian, Lin, Ren, Wang, Zhi-xiang, Zhao, Ke, Wang, Qiang, Zhou, Xuan, Fan, Zhi-ping, Huang, Fen, Xu, Na, Xuan, Li, Jin, Hua, Sun, Jing, Gale, Robert Peter, Zhou, Hong-sheng, Liu, Qi-fa
Published in Bone marrow transplantation (Basingstoke) (01.11.2022)
Published in Bone marrow transplantation (Basingstoke) (01.11.2022)
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