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Small molecule metabolites: discovery of biomarkers and therapeutic targets
Qiu, Shi, Cai, Ying, Yao, Hong, Lin, Chunsheng, Xie, Yiqiang, Tang, Songqi, Zhang, Aihua
Published in Signal transduction and targeted therapy (20.03.2023)
Published in Signal transduction and targeted therapy (20.03.2023)
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Are sirtuins viable targets for improving healthspan and lifespan?
Baur, Joseph A., Ungvari, Zoltan, Minor, Robin K., Le Couteur, David G., de Cabo, Rafael
Published in Nature reviews. Drug discovery (01.06.2012)
Published in Nature reviews. Drug discovery (01.06.2012)
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In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα
Li, Benjamin Xiaoyi, Dai, Xiangrong, Xu, Xiaohong Ruby, Adili, Reheman, Neves, Miguel Antonio Dias, Lei, Xi, Shen, Chuanbin, Zhu, Guangheng, Wang, Yiming, Zhou, Hui, Hou, Yan, Ni, Tiffany, Pasman, Yfke, Yang, Zhongqiang, Qian, Fang, Zhao, Yanan, Gao, Yongxiang, Liu, Jing, Teng, Maikun, Marshall, Alexandra H., Cerenzia, Eric G., Li, Mandy Lokyee, Ni, Heyu
Published in Scientific reports (03.06.2021)
Published in Scientific reports (03.06.2021)
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Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas
Whitson, Ramon J, Lee, Alex, Urman, Nicole M, Mirza, Amar, Yao, Catherine Y, Brown, Alexander S, Li, Jiang R, Shankar, Gautam, Fry, Micah A, Atwood, Scott X, Lee, Eunice Y, Hollmig, S Tyler, Aasi, Sumaira Z, Sarin, Kavita Y, Scott, Matthew P, Epstein, Jr, Ervin H, Tang, Jean Y, Oro, Anthony E
Published in Nature medicine (01.03.2018)
Published in Nature medicine (01.03.2018)
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Targeting the NTSR2/TrkB oncogenic pathway in chronic lymphocytic leukemia
Ikhlef, Léa, Yassine, May, Chandouri, Boutaîna, Rivière, Léa, Naves, Thomas, Dmytruk, Natalya, Gachard, Nathalie, Jauberteau, Marie-Odile, Gallet, Paul-François
Published in Scientific reports (13.03.2024)
Published in Scientific reports (13.03.2024)
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Comprehensive multi-omics analysis reveals the core role of glycerophospholipid metabolism in the influence of short-chain fatty acids on the development of sepsis
Tian, Yunfen, Sun, Meisha, Luo, Lan, Lou, Fen, Zhou, Peng, Chen, Jiejuan, Lv, Hongdan, Zhang, Fangxiang, Zhang, Mazhong, Wang, Bin
Published in Scientific reports (09.08.2025)
Published in Scientific reports (09.08.2025)
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Prediction of severe adverse events, modes of action and drug treatments for COVID-19’s complications
Astore, Courtney, Zhou, Hongyi, Jacob, Joshy, Skolnick, Jeffrey
Published in Scientific reports (21.10.2021)
Published in Scientific reports (21.10.2021)
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Insulin induces insulin receptor degradation in the liver through EphB4
Liu, Xingfeng, Wang, Kai, Hou, Shaocong, Jiang, Qian, Ma, Chunxiao, Zhao, Qijin, Kong, Lijuan, Chen, Jingwen, Wang, Zhenhe, Zhang, Huabing, Yuan, Tao, Li, Yuxiu, Huan, Yi, Shen, Zhufang, Hu, Zhuowei, Huang, Zhifeng, Cui, Bing, Li, Pingping
Published in Nature metabolism (01.09.2022)
Published in Nature metabolism (01.09.2022)
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Dual PI3K and Wnt pathway inhibition is a synergistic combination against triple negative breast cancer
Solzak, Jeffrey P., Atale, Rutuja V., Hancock, Bradley A., Sinn, Anthony L., Pollok, Karen E., Jones, David R., Radovich, Milan
Published in NPJ breast cancer (26.04.2017)
Published in NPJ breast cancer (26.04.2017)
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Proteomic signatures of myeloid derived suppressor cells from liver and lung metastases reveal functional divergence and potential therapeutic targets
DaSilva, Nicholas A., Barlock, Benjamin J., Guha, Prajna, Ghosh, Chandra C., Trebino, Catherine E., Camberg, Jodi L., Katz, Steven C., Rowley, David C.
Published in Cell death discovery (04.09.2021)
Published in Cell death discovery (04.09.2021)
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