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A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis
Zhang, Mingming, Zhou, Lixing, Xu, Yuejie, Yang, Min, Xu, Yilai, Komaniecki, Garrison Paul, Kosciuk, Tatsiana, Chen, Xiao, Lu, Xuan, Zou, Xiaoping, Linder, Maurine E., Lin, Hening
Published in Nature (London) (15.10.2020)
Published in Nature (London) (15.10.2020)
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Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
Bonner, Caroline, Kerr-Conte, Julie, Gmyr, Valéry, Queniat, Gurvan, Moerman, Ericka, Thévenet, Julien, Beaucamps, Cédric, Delalleau, Nathalie, Popescu, Iuliana, Malaisse, Willy J, Sener, Abdullah, Deprez, Benoit, Abderrahmani, Amar, Staels, Bart, Pattou, François
Published in Nature medicine (01.05.2015)
Published in Nature medicine (01.05.2015)
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Histidine catabolism is a major determinant of methotrexate sensitivity
Kanarek, Naama, Keys, Heather R., Cantor, Jason R., Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Freinkman, Elizaveta, Schweitzer, Lawrence D., Sabatini, David M.
Published in Nature (London) (01.07.2018)
Published in Nature (London) (01.07.2018)
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SKP2- and OTUD1-regulated non-proteolytic ubiquitination of YAP promotes YAP nuclear localization and activity
Yao, Fan, Zhou, Zhicheng, Kim, Jongchan, Hang, Qinglei, Xiao, Zhenna, Ton, Baochau N., Chang, Liang, Liu, Na, Zeng, Liyong, Wang, Wenqi, Wang, Yumeng, Zhang, Peijing, Hu, Xiaoyu, Su, Xiaohua, Liang, Han, Sun, Yutong, Ma, Li
Published in Nature communications (11.06.2018)
Published in Nature communications (11.06.2018)
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An obligatory role for neurotensin in high-fat-diet-induced obesity
Li, Jing, Song, Jun, Zaytseva, Yekaterina Y., Liu, Yajuan, Rychahou, Piotr, Jiang, Kai, Starr, Marlene E., Kim, Ji Tae, Harris, Jennifer W., Yiannikouris, Frederique B., Katz, Wendy S., Nilsson, Peter M., Orho-Melander, Marju, Chen, Jing, Zhu, Haining, Fahrenholz, Timothy, Higashi, Richard M., Gao, Tianyan, Morris, Andrew J., Cassis, Lisa A., Fan, Teresa W. -M., Weiss, Heidi L., Dobner, Paul R., Melander, Olle, Jia, Jianhang, Evers, B. Mark
Published in Nature (London) (19.05.2016)
Published in Nature (London) (19.05.2016)
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Encoding gene RAB3B exists in linear chromosomal and circular extrachromosomal DNA and contributes to cisplatin resistance of hypopharyngeal squamous cell carcinoma via inducing autophagy
Lin, Changwei, Chen, Yifei, Zhang, Fan, Liu, Baiying, Xie, Canbin, Song, Yexun
Published in Cell death & disease (22.02.2022)
Published in Cell death & disease (22.02.2022)
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Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
Michailidou, Kyriaki, Thompson, Deborah, French, Juliet D, Pooley, Karen A, Dicks, Ed, Barrowdale, Daniel, Sinnott-Armstrong, Nicholas A, Kaufmann, Susanne, Sivakumaran, Haran, Lee, Jason S, Hills, Margaret, Jarosz, Monika, Wang, Qin, Hopper, John L, Southey, Melissa C, Broeks, Annegien, Lophatananon, Artitaya, Beckmann, Matthias W, Fasching, Peter A, dos-Santos-Silva, Isabel, Peto, Julian, Guénel, Pascal, Bojesen, Stig E, Flyger, Henrik, González-Neira, Anna, Anton-Culver, Hoda, Eunjung, Lee, Arndt, Volker, Brenner, Hermann, Meindl, Alfons, Brauch, Hiltrud, Aittomäki, Kristiina, Matsuo, Keitaro, Dörk, Thilo, Margolin, Sara, Mannermaa, Arto, Lambrechts, Diether, Radice, Paolo, Haiman, Christopher A, Nord, Silje, Pylkäs, Katri, Winqvist, Robert, Knight, Julia A, Figueroa, Jonine, van den Ouweland, Ans M W, Gao, Yu-Tang, Shu, Xiao-Ou, Cross, Simon S, Cai, Qiuyin, Ghoussaini, Maya, Kang, Daehee, Lee, Soo Chin, Shen, Chen-Yang, Wu, Pei-Ei, Healey, Sue, Terry, Mary Beth, Goldgar, David E, Buys, Saundra S, Janavicius, Ramunas, Hansen, Thomas V O, Benitez, Javier, Weitzel, Jeffrey N, Bonanni, Bernardo, Peissel, Bernard, Manoukian, Siranoush, Papi, Laura, Ottini, Laura, Frost, Debra, Niederacher, Dieter, Sinilnikova, Olga M, De Leeneer, Kim, de la Hoya, Miguel, Nevanlinna, Heli, Khan, Sofia, Kwong, Ava, Diez, Orland, Brunet, Joan, Gronwald, Jacek, Huzarski, Tomasz, Barkardottir, Rosa B, Laframboise, Rachel, Park, Sue Kyung, Foretova, Lenka, Vijai, Joseph, Singer, Christian F, Mai, Phuong L, Hulick, Peter J, Glendon, Gord, Laitman, Yael, von Wachenfeldt, Anna, Nussbaum, Robert L, Gayther, Simon A, Domchek, Susan M, Arun, Banu K, Karlan, Beth Y, Woolcott, Christy, Stone, Jennifer, Luben, Robert, Dowsett, Mitch, Antoniou, Antonis C
Published in Nature genetics (01.04.2016)
Published in Nature genetics (01.04.2016)
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Huntington's disease is a four-repeat tauopathy with tau nuclear rods
Fernández-Nogales, Marta, Cabrera, Jorge R, Santos-Galindo, María, Hoozemans, Jeroen J M, Ferrer, Isidro, Rozemuller, Annemieke J M, Hernández, Félix, Avila, Jesús, Lucas, José J
Published in Nature medicine (01.08.2014)
Published in Nature medicine (01.08.2014)
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Plasticity and redundancy among AMA–RON pairs ensure host cell entry of Toxoplasma parasites
Lamarque, Mauld H., Roques, Magali, Kong-Hap, Marie, Tonkin, Michelle L., Rugarabamu, George, Marq, Jean-Baptiste, Penarete-Vargas, Diana M., Boulanger, Martin J., Soldati-Favre, Dominique, Lebrun, Maryse
Published in Nature communications (17.06.2014)
Published in Nature communications (17.06.2014)
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17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells
Schmiedel, Benjamin Joachim, Seumois, Grégory, Samaniego-Castruita, Daniela, Cayford, Justin, Schulten, Veronique, Chavez, Lukas, Ay, Ferhat, Sette, Alessandro, Peters, Bjoern, Vijayanand, Pandurangan
Published in Nature communications (16.11.2016)
Published in Nature communications (16.11.2016)
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De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands
Masalmeh, Roza H. Ali, Taglini, Francesca, Rubio-Ramon, Cristina, Musialik, Kamila I., Higham, Jonathan, Davidson-Smith, Hazel, Kafetzopoulos, Ioannis, Pawlicka, Kamila P., Finan, Hannah M., Clark, Richard, Wills, Jimi, Finch, Andrew J., Murphy, Lee, Sproul, Duncan
Published in Nature communications (29.01.2021)
Published in Nature communications (29.01.2021)
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Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities
Li, Hong, Zhu, Ying, Morozov, Yury M., Chen, Xiaoli, Page, Stephanie Cerceo, Rannals, Matthew D., Maher, Brady J., Rakic, Pasko
Published in Molecular psychiatry (01.08.2019)
Published in Molecular psychiatry (01.08.2019)
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Nuclear retention of unspliced HIV-1 RNA as a reversible post-transcriptional block in latency
Dorman, Agnieszka, Bendoumou, Maryam, Valaitienė, Aurelija, Wadas, Jakub, Ali, Haider, Dutilleul, Antoine, Maiuri, Paolo, Nestola, Lorena, Bociaga-Jasik, Monika, Mchantaf, Gilbert, Necsoi, Coca, De Wit, Stéphane, Avettand-Fenoël, Véronique, Marcello, Alessandro, Pyrc, Krzysztof, Pasternak, Alexander O., Van Lint, Carine, Kula-Pacurar, Anna
Published in Nature communications (28.02.2025)
Published in Nature communications (28.02.2025)
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The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel
Stephan, Gabriele, Huang, Lumei, Tang, Yong, Vilotti, Sandra, Fabbretti, Elsa, Yu, Ye, Nörenberg, Wolfgang, Franke, Heike, Gölöncsér, Flóra, Sperlágh, Beáta, Dopychai, Anke, Hausmann, Ralf, Schmalzing, Günther, Rubini, Patrizia, Illes, Peter
Published in Nature communications (10.04.2018)
Published in Nature communications (10.04.2018)
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Ghrelin-induced neuronal NPY promotes brain metastasis in lung cancer patients with low BMI
Tyagi, Abhishek, Wu, Shih-Ying, Kim, Jee-Won, Deshpande, Ravindra Pramod, Wu, Kerui, Smith, Eleanor C., Banna, Giuseppe L., Watabe, Kounosuke
Published in Nature communications (01.07.2025)
Published in Nature communications (01.07.2025)
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Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation
Ghoussaini, Maya, Edwards, Stacey L., Hillman, Kristine M., Kaufmann, Susanne, Beesley, Jonathan, Dennis, Joe, Bolla, Manjeet K., Dicks, Ed, Guo, Qi, Schmidt, Marjanka K., Shah, Mitul, Luben, Robert, Darabi, Hatef, Eriksson, Mikael, Bojesen, Stig E., Nordestgaard, Børge G., Lambrechts, Diether, Neven, Patrick, Wildiers, Hans, Th Rutgers, Emiel J., Couch, Fergus J., Hallberg, Emily, Vachon, Celine, Seibold, Petra, Flesch-Janys, Dieter, dos-Santos-Silva, Isabel, Gibson, Lorna, Nevanlinna, Heli, Aittomäki, Kristiina, Blomqvist, Carl, Hall, Per, Kang, Daehee, Park, Sue K., Iwata, Hiroji, Truong, Thérèse, Menegaux, Florence, Burwinkel, Barbara, Marme, Frederik, Sohn, Christof, Tseng, Chiu-chen, Van Den Berg, David, Stram, Daniel O., Perez, Jose Ignacio Arias, Shu, Xiao-Ou, Cai, Qiuyin, Reed, Malcolm W. R., Tchatchou, Sandrine, Sawyer, Elinor J., Kerin, Michael J., Henderson, Brian E., YIP, Cheng Har, Wong, Tien Y., Martens, John W. M., Hopper, John L., Tsimiklis, Helen, Kapuscinski, Miroslav K., Shen, Chen-Yang, Giles, Graham G., Hartman, Mikael, Haeberle, Lothar, Ekici, Arif B., Ashworth, Alan, García-Closas, Montserrat, Lissowska, Jolanta, Simard, Jacques, Goldberg, Mark S., Labrèche, France, Dumont, Martine, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Brauch, Hiltrud, Brüning, Thomas, Radice, Paolo, Volorio, Sara, Helbig, Sonja, Mannermaa, Arto, Kataja, Vesa, Tollenaar, Robert A. E. M., Seynaeve, Caroline, Jaworska-Bieniek, Katarzyna, Toland, Amanda E., Ambrosone, Christine B., Yannoukakos, Drakoulis, Sangrajrang, Suleeporn, McKay, James, Long, Jirong, Anton-Culver, Hoda, Neuhausen, Susan L., Baynes, Caroline, Ahmed, Shahana, Maranian, Mel, González-Neira, Anna, Herrero, Daniel, Vincent, Daniel, Carroll, Jason, Caldas, Carlos, Brown, Melissa A., Lupien, Mathieu, Kristensen, Vessela N., Easton, Douglas F.
Published in Nature communications (23.09.2014)
Published in Nature communications (23.09.2014)
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The dual mechanism of m6A demethylase ALKBH5 in regulating energy metabolism during exposure to MC-LR
Sun, Xiaoya, Tan, Qinmei, Yang, Yue, Wei, Jia, Zhou, Xiaodie, Gao, Shanshan, Yang, Fei
Published in Cell death & disease (03.07.2025)
Published in Cell death & disease (03.07.2025)
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