Activity and rational combinations of a novel, engineered chimeric, TRAIL-based ligand in diffuse large B-cell lymphoma
Piechna, Karolina, Żołyniak, Aleksandra, Jabłońska, Ewa, Noyszewska-Kania, Monika, Szydłowski, Maciej, Żerek, Bartłomiej, Kulecka, Maria, Rumieńczyk, Izabela, Mikula, Michał, Juszczyński, Przemysław
Published in Frontiers in oncology (31.10.2022)
Published in Frontiers in oncology (31.10.2022)
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Journal Article
AD-O53.2—a novel recombinant fusion protein combining the activities of TRAIL/Apo2L and Smac/Diablo, overcomes resistance of human cancer cells to TRAIL/Apo2L
Pieczykolan, Jerzy S., Kubiński, Konrad, Masłyk, Maciej, Pawlak, Sebastian D., Pieczykolan, Anna, Rózga, Piotr K., Szymanik, Michał, Gałązka, Marlena, Teska-Kamińska, Małgorzata, Żerek, Bartłomiej, Bukato, Katarzyna, Poleszak, Katarzyna, Jaworski, Albert, Strożek, Wojciech, Świder, Robert, Zieliński, Rafał
Published in Investigational new drugs (01.12.2014)
Published in Investigational new drugs (01.12.2014)
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Journal Article
Improved cytotoxicity of novel TRAIL variants produced as recombinant fusion proteins
Figiel, Małgorzata, Bonarek, Piotr, Górecki, Andrzej, Pawlak, Sebastian D, Żerek, Bartłomiej, Chęcińska, Beata, Pieczykolan, Jerzy, Dziedzicka-Wasylewska, Marta
Published in Protein engineering, design and selection (01.02.2018)
Published in Protein engineering, design and selection (01.02.2018)
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Journal Article
The evolution of biologics in the context of oncological therapy
Żerek, Bartłomiej, Straś, Wojciech, Rózga, Piotr, Pękala, Elżbieta
Published in Oncology in Clinical Practice (01.01.2020)
Published in Oncology in Clinical Practice (01.01.2020)
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Journal Article
An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study
Sidoryk, Katarzyna, Świtalska, Marta, Rózga, Piotr, Wietrzyk, Joanna, Bujak, Iwona, Żerek, Bartłomiej, Kaczmarek, Łukasz, Cybulski, Marcin
Published in Medicinal chemistry research (2017)
Published in Medicinal chemistry research (2017)
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Journal Article
Abstract 2276: Induction of apoptosis and inhibition of angiogenesis by novel fusion protein - AD-O54.9 as a new preclinical strategy in cancer treatment
Rózga, Piotr, Pieczykolan, Jerzy, Zerek, Bartłomiej, Pieczykolan, Anna, Gałązka, Marlena, Bukato, Katarzyna, Szymanik, Michał, Jaworski, Albert, Pawlak, Sebastian, Teska-Kamińska, Małgorzata, Grochot-Przęczek, Anna
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
ANTICANCER FUSION PROTEIN
RÓZGA PIOTR KAMIL, PIECZYKOLAN JERZY SZCZEPAN, ŻEREK BARTŁOMIEJ MACIEJ, PAWLAK SEBASTIAN DOMINIK
Year of Publication 30.03.2018
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Year of Publication 30.03.2018
Patent
AD-053.2—a novel recombinant fusion protein combining the activities of TRAIL/Apo2L and Smac/Diablo, overcomes resistance of human cancer cells to TRAIL/Apo2L
PIECZYKOLAN, Jerzy S, KUBINSKI, Konrad, BUKATO, Katarzyna, POLESZAK, Katarzyna, JAWORSKI, Albert, STROZEK, Wojciech, SWIDER, Robert, ZIELINSKI, Rafał, MASLYK, Maciej, PAWLAK, Sebastian D, PIECZYKOLAN, Anna, ROZGA, Piotr K, SZYMANIK, Michał, GALAZKA, Marlena, TESKA-KAMINSKA, Małgorzata, ZEREK, Bartłomiej
Published in Investigational new drugs (2014)
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Published in Investigational new drugs (2014)
Journal Article
ANTICANCER FUSION PROTEIN
RÓZGA PIOTR KAMIL, PIECZYKOLAN JERZY SZCZEPAN, ŻEREK BARTŁOMIEJ MACIEJ, PAWLAK SEBASTIAN DOMINIK
Year of Publication 31.08.2017
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Year of Publication 31.08.2017
Patent
Anti-tumor fusion protein
RÓZGA PIOTR KAMIL, PIECZYKOLAN JERZY SZCZEPAN, PAWLAK SEBASTIAN DOMINIK, ŻEREK BARTŁOMIEJ
Year of Publication 31.10.2016
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Year of Publication 31.10.2016
Patent
Anticancer fusion protein
Rózga Piotr Kamil, Żerek Bartłomiej Maciej, Pawlak Sebastian Dominik, Pieczykolan Jerzy Szczepan
Year of Publication 27.06.2014
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Year of Publication 27.06.2014
Patent
Novel engineered TRAIL‐based chimeric protein strongly inhibits tumor growth and bypasses TRAIL resistance
Rozga, Piotr, Kloska, Damian, Pawlak, Sebastian, Teska‐Kaminska, Malgorzata, Galazka, Marlena, Bukato, Katarzyna, Pieczykolan, Anna, Jaworski, Albert, Molga‐Kaczmarska, Anna, Kopacz, Aleksandra, Badyra, Bogna, Kachamakova‐Trojanowska, Neli, Zolnierkiewicz, Olga, Targosz‐Korecka, Marta, Poleszak, Katarzyna, Szymanik, Michal, Zerek, Bartlomiej, Pieczykolan, Jerzy, Jozkowicz, Alicja, Grochot‐Przeczek, Anna
Published in International journal of cancer (15.08.2020)
Published in International journal of cancer (15.08.2020)
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Journal Article
Abstract 4471: AD-O64.4 - a novel bioconjugate for tumor-targeted drug delivery
Strozek, Wojciech, Pieczykolan, Anna, Zerek, Bartlomiej, Szymanik, Michal, Jaworski, Albert, Galazka, Marlena, Bukato, Katarzyna, Rozga, Piotr, Pawlak, Sebastian, Poleszak, Katarzyna, Teska-Kaminska, Malgorzata, Pieczykolan, Jerzy
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract 3796: Biochemical and biophysical characterization of AD-O51.4 a novel anticancer biological therapeutic agent with dual mechanism of action
Pawlak, Sebastian D., Pieczykolan, Jerzy S., Zerek, Bartlomiej, Poleszak, Katarzyna, Teska-Kaminska, Malgorzata, Galaska, Marlena, Szymanik, Michal, Jaworski, Albert, Pieczykolan, Anna, Bukato, Katarzyna, Strozek, Wojciech, Rozga, Piotr K.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract 2600: Preclinical evaluation of the novel fusion molecule with high dual antiangiogenic and anticancer potential
Pieczykolan, Jerzy S., Pieczykolan, Anna, Rozga, Piotr, Pawlak, Sebastian, Zerek, Bartlomiej, Teska - Kaminska, Malgorzata, Michal, Szymanik, Jaworski, Albert, Erlemann, Karl R., Capala, Jacek
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract 2773: AD-O56.9: A fusion of TRAIL/Apo2L with a membrane disrupting peptide as a novel anticancer therapeutic
Zerek, Bartlomiej Maciej, Szymanik, Michal, Rozga, Piotr Kamil, Pieczykolan, Anna, Galazka, Marlena, Bukato, Katarzyna, Jaworski, Albert, Poleszak, Katarzyna, Pawlak, Sebastian Dominik, Teska-Kaminska, Malgorzata, Strozek, Wojciech, Pieczykolan, Jerzy Szczepan
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract 5488: Fusion protein capable to initiate two apoptotic pathways in cancer cells resistant to classical PARA's
Pieczykolan, Jerzy S., Pawlak, Sebastian D., Zerek, Bartlomiej M., Rozga, Piotr K., Pieczykolan, Anna, Szymanik, Michal, Jaworski, Albert, Galazka, Marlena, Strozek, Wojciech, Wiciejowska, Katarzyna, Teska-Kaminska, Malgorzata, Kutner, Lukasz
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Abstract 5073: Novel fusion molecule with high dual antiangiogenic and anticancer potential
Pieczykolan, Jerzy S., Rozga, Piotr, Pieczykolan, Anna, Zerek, Bartlomiej, Pawlak, Sebastian D., Szymanik, Michal, Jaworski, Albert, Galazka, Marlena, Wiciejowska, Katarzyna, Strozek, Wojciech, Teska - Kaminska, Malgorzata, Kutner, Lukasz, Grochot - Przeczek, Anna, Kahmakowa - Trojanowska, Neli
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
ANTICANCER FUSION PROTEIN
PIECZYKOLAN, JERZY SZCZEPAN, ŹEREK, BARTŁOMIEJ, PAWLAK, SEBASTIAN, LEMKE, KRZYSZTOF KAZIMIERZ
Year of Publication 30.10.2015
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Year of Publication 30.10.2015
Patent
Anticancer fusion protein
Lemke Krzysztof Kazimierz, Pawlak Sebastian, Pieczykolan Jerzy Szczepan, Źerek Bartłomiej
Year of Publication 30.05.2014
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Year of Publication 30.05.2014
Patent