Buparlisib is a brain penetrable pan-PI3K inhibitor
de Gooijer, Mark C, Zhang, Ping, Buil, Levi C M, Çitirikkaya, Ceren H, Thota, Nishita, Beijnen, Jos H, van Tellingen, Olaf
Published in Scientific reports (17.07.2018)
Published in Scientific reports (17.07.2018)
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Journal Article
ABCB1 Attenuates the Brain Penetration of the PARP Inhibitor AZD2461
de Gooijer, Mark C, Buil, Levi C.M, Çitirikkaya, Ceren H, Hermans, Jill, Beijnen, Jos H, van Tellingen, Olaf
Published in Molecular pharmaceutics (05.11.2018)
Published in Molecular pharmaceutics (05.11.2018)
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Journal Article
ATP-binding cassette transporter inhibitor potency and substrate drug affinity are critical determinants of successful drug delivery enhancement to the brain
Lentzas, Aristeidis, de Gooijer, Mark C, Zuidema, Stefanie, Meurs, Amber, Çitirikkaya, Ceren H, Venekamp, Nikkie, Beijnen, Jos H, van Tellingen, Olaf
Published in Fluids and barriers of the CNS (05.08.2024)
Published in Fluids and barriers of the CNS (05.08.2024)
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Journal Article
ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost
de Gooijer, Mark C., Kemper, E. Marleen, Buil, Levi C.M., Çitirikkaya, Ceren H., Buckle, Tessa, Beijnen, Jos H., van Tellingen, Olaf
Published in Cell reports. Medicine (19.01.2021)
Published in Cell reports. Medicine (19.01.2021)
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Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
Uceda-Castro, Rebeca, Margarido, Andreia S., Cornet, Lesley, Vegna, Serena, Hahn, Kerstin, Song, Ji-Ying, Putavet, Diana A., van Geldorp, Mariska, Çitirikkaya, Ceren H., de Keizer, Peter L.J., ter Beek, Leon C., Borst, Gerben R., Akkari, Leila, van Tellingen, Olaf, Broekman, Marike L.D., Vennin, Claire, van Rheenen, Jacco
Published in Cell reports. Medicine (15.11.2022)
Published in Cell reports. Medicine (15.11.2022)
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Journal Article
BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis
Uceda-Castro, Rebeca, Margarido, Andreia S., Song, Ji-Ying, de Gooijer, Mark C., Messal, Hendrik A., Chambers, Cecilia R., Nobis, Max, Çitirikkaya, Ceren H., Hahn, Kerstin, Seinstra, Danielle, Herrmann, David, Timpson, Paul, Wesseling, Pieter, van Tellingen, Olaf, Vennin, Claire, van Rheenen, Jacco
Published in Science advances (20.10.2023)
Published in Science advances (20.10.2023)
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Journal Article
Abstract PO-003: Mitotic enrichment as an efficient radiosensitization strategy
de Gooijer, Mark C., Slangen, Paul L.G., Çolakoğlu, Hilal, Çitirikkaya, Ceren H., El Ouazani, Amal, Shah, Ronak, Borst, Gerben R., van Tellingen, Olaf
Published in Clinical cancer research (15.04.2021)
Published in Clinical cancer research (15.04.2021)
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EXTH-72. CONTINUOUS INFUSION STUDIES REVEAL THE POTENCY OF ELACRIDAR TO ACT AS A PHARMACO-ENHANCER FOR TREATMENT OF INTRACRANIAL DISEASES BY INHIBITING ABCB1 AND ABCG2 AT THE BLOOD-BRAIN BARRIER
van Tellingen, Olaf, de Gooijer, Mark C, Zuidema, Stefanie, Meurs, Amber, Çitirikkaya, Ceren H, Venekamp, Nikkie, Beijnen, Jos H
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
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Journal Article
RBIO-05. MITOTIC ENRICHMENT AS AN EFFICIENT STRATEGY TO RADIOSENSITIZE GLIOBLASTOMA
de Gooijer, Mark C, Slangen, Paul L G, Çitirikkaya, Ceren H, Çolakoğlu, Hilal, El Ouazani, Amal, Shah, Ronak, Borst, Gerben R, van Tellingen, Olaf
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
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Journal Article
DDRE-32. ABC TRANSPORTERS RESTRICT THE BRAIN PENETRATION AND INTRACRANIAL EFFICACY OF ANTICANCER AGENTS EVEN WHEN BLOOD-BRAIN BARRIER INTEGRITY IS LOST
de Gooijer, Mark C, Kemper, E Marleen, Buil, Levi C M, Çitirikkaya, Ceren H, Buckle, Tessa, Beijnen, Jos H, van Tellingen, Olaf
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
Published in Neuro-oncology (Charlottesville, Va.) (09.11.2020)
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