Protumorigenic effects of Snail‐expression fibroblasts on colon cancer cells
Herrera, Alberto, Herrera, Mercedes, Alba‐Castellón, Lorena, Silva, Javier, García, Vanesa, Loubat‐Casanovas, Jordina, Álvarez‐Cienfuegos, Ana, Miguel García, José, Rodriguez, Rufo, Gil, Beatriz, Ma Jesús Citores, Ma Jesús Larriba, Ignacio Casal, J., Herreros, Antonio García, Bonilla, Félix, Peña, Cristina
Published in International journal of cancer (15.06.2014)
Published in International journal of cancer (15.06.2014)
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Journal Article
Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes
Guijarro-Muñoz, Irene, Compte, Marta, Álvarez-Cienfuegos, Ana, Álvarez-Vallina, Luis, Sanz, Laura
Published in The Journal of biological chemistry (24.01.2014)
Published in The Journal of biological chemistry (24.01.2014)
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Journal Article
Basement membrane-rich organoids with functional human blood vessels are permissive niches for human breast cancer metastasis
Fernández-Periáñez, Rodrigo, Molina-Privado, Irene, Rojo, Federico, Guijarro-Muñoz, Irene, Alonso-Camino, Vanesa, Zazo, Sandra, Compte, Marta, Alvarez-Cienfuegos, Ana, Cuesta, Angel M, Sánchez-Martín, David, Alvarez-Méndez, Ana M, Sanz, Laura, Alvarez-Vallina, Luis
Published in PloS one (08.08.2013)
Published in PloS one (08.08.2013)
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Journal Article
Efficient production of single-chain fragment variable-based N-terminal trimerbodies in Pichia pastoris
Blanco-Toribio, Ana, Lacadena, Javier, Nuñez-Prado, Natalia, Álvarez-Cienfuegos, Ana, Villate, Maider, Compte, Marta, Sanz, Laura, Blanco, Francisco J, Álvarez-Vallina, Luis
Published in Microbial cell factories (12.08.2014)
Published in Microbial cell factories (12.08.2014)
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Journal Article
The heterotrimeric laminin coiled-coil domain exerts anti-adhesive effects and induces a pro-invasive phenotype
Santos-Valle, Patricia, Guijarro-Muñoz, Irene, Cuesta, Angel M, Alonso-Camino, Vanesa, Villate, Maider, Alvarez-Cienfuegos, Ana, Blanco, Francisco J, Sanz, Laura, Alvarez-Vallina, Luis
Published in PloS one (19.06.2012)
Published in PloS one (19.06.2012)
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Journal Article
Improved stability of multivalent antibodies containing the human collagen XV trimerization domain
Cuesta, Ángel M., Sánchez-Martín, David, Blanco-Toribio, Ana, Villate, Maider, Enciso-Álvarez, Kelly, Álvarez-Cienfuegos, Ana, Sainz-Pastor, Noelia, Sanz, Laura, Blanco, Francisco J., Álvarez-Vallina, Luis
Published in mAbs (01.03.2012)
Published in mAbs (01.03.2012)
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Journal Article
Functional comparison of single-chain and two-chain anti-CD3-based bispecific antibodies in gene immunotherapy applications
Compte, Marta, Álvarez-Cienfuegos, Ana, Nuñez-Prado, Natalia, Sainz-Pastor, Noelia, Blanco-Toribio, Ana, Pescador, Nuria, Sanz, Laura, Álvarez-Vallina, Luis
Published in Oncoimmunology (01.05.2014)
Published in Oncoimmunology (01.05.2014)
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Journal Article
Generation and characterization of monospecific and bispecific hexavalent trimerbodies
Blanco-Toribio, Ana, Sainz-Pastor, Noelia, Álvarez-Cienfuegos, Ana, Merino, Nekane, Cuesta, Ángel M., Sánchez-Martín, David, Bonet, Jaume, Santos-Valle, Patricia, Sanz, Laura, Oliva, Baldo, Blanco, Francisco J., Álvarez-Vallina, Luis
Published in mAbs (01.01.2013)
Published in mAbs (01.01.2013)
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Journal Article
Bacterial secretion of soluble and functional trivalent scFv-based N-terminal trimerbodies
Blanco-Toribio, Ana, Álvarez-Cienfuegos, Ana, Sainz-Pastor, Noelia, Merino, Nekane, Compte, Marta, Sanz, Laura, Blanco, Francisco J, Álvarez-Vallina, Luis
Published in AMB Express (04.08.2015)
Published in AMB Express (04.08.2015)
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Journal Article
ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy
Harwood, Seandean Lykke, Alvarez-Cienfuegos, Ana, Nuñez-Prado, Natalia, Compte, Marta, Hernández-Pérez, Sara, Merino, Nekane, Bonet, Jaume, Navarro, Rocio, Van Bergen en Henegouwen, Paul M. P., Lykkemark, Simon, Mikkelsen, Kasper, Mølgaard, Kasper, Jabs, Frederic, Sanz, Laura, Blanco, Francisco J., Roda-Navarro, Pedro, Alvarez-Vallina, Luis
Published in Oncoimmunology (02.01.2018)
Published in Oncoimmunology (02.01.2018)
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Journal Article
Development of a human immuno-oncology therapeutic agent targeting HER2: targeted delivery of granzyme B
Cheung, Lawrence H, Zhao, Yunli, Alvarez-Cienfuegos, Ana, Mohamedali, Khalid A, Cao, Yu J, Hittelman, Walter N, Rosenblum, Michael G
Published in Journal of experimental & clinical cancer research (30.07.2019)
Published in Journal of experimental & clinical cancer research (30.07.2019)
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Journal Article
Lipopolysaccharide Activates Toll-like Receptor 4 (TLR4)-mediated NF-κB Signaling Pathway and Proinflammatory Response in Human PericytesThis work was supported by Fondo de Investigaciones Sanitarias/Instituto de Salud Carlos III Grants PI08/90856 and PS09/00227 and Fundación Investigación Biomédica Hospital Puerta de Hierro (to L. S.) and by Ministerio de Economía y Competitividad Grant BIO2011-22738 and Comunidad de Madrid Grant S2010/BMD-2312 (to L. A.-V.)
Guijarro-Muñoz, Irene, Compte, Marta, Álvarez-Cienfuegos, Ana, Álvarez-Vallina, Luis, Sanz, Laura
Published in The Journal of biological chemistry (24.01.2014)
Published in The Journal of biological chemistry (24.01.2014)
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Journal Article
Abstract 5194: Development of a cytotoxic fusion protein targeting VEGF receptors with improved cytotoxicity, stability and pharmacokinetics
Mohamedali, Khalid A., Cheung, Lawrence H., Alvarez-Cienfuegos, Ana A., Rosenblum, Michael G.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 5176: A novel, completely human fusion construct containing active Granzyme B efficiently kills Folate Receptor alpha positive tumor cells
de Cienfuegos, Ana Alvarez, Cheung, Laurence H., Mohamedali, Khalid A., Hittelman, Walter N., Rosenblum, Michael G.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Generation and characterization of monospecific and bispecific hexavalent trimerbodies
Ana Blanco-Toribio, David Sánchez-Martín, Baldo Oliva, Jaume Bonet, Nekane Merino, Ángel M. Cuesta, Patricia Santos-Valle, Francisco J. Blanco, Laura Sanz, Noelia Sainz-Pastor, Ana Álvarez-Cienfuegos, Luis Álvarez-Vallina
Published in mAbs (01.01.2013)
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Published in mAbs (01.01.2013)
Journal Article
Abstract 2396: Development of a new generation of dimeric, highly cytotoxic fusion proteins containing active GrB and VEGF targeting tumor neovasculature: Incorporating IgG heavy chain Fc fragments improves cytotoxicity, stability and pharmacokinetics
Mohamedali, Khalid A., Cheung, Lawrence H., Alvarez-Cienfuegos, Ana, Rosenblum, Michael G.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 2603: Targeting chemo-resistant ovarian cancer with a first-in-class, first-in-human immune-oncology agents containing granzyme B
Alvarez-Cienfuegos, Ana, Cheung, Lawrence H., Mohamedali, Khalid A., Rosenblum, Michael G.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 5974: Targeting VEGFR on tumor cells and activated vasculature through delivery of granzyme B
Mohamedali, Khalid A., Cheung, Lawrence H., Alvarez-Cienfuegos, Ana, Hittelman, Walter N., Rosenblum, Michael G.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Journal Article
Abstract 5615: Genomic differential expression analysis of fusion proteins incorporating the pro-apoptotic molecule Granzyme B reveals new potential targets for treatment of breast cancer
Mohamedali, Khalid A., Cheung, Lawrence H., Alvarez-Cienfuegos, Ana, Rosenblum, Michael G.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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