Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Chamberlain, Philip P, Lopez-Girona, Antonia, Miller, Karen, Carmel, Gilles, Pagarigan, Barbra, Chie-Leon, Barbara, Rychak, Emily, Corral, Laura G, Ren, Yan J, Wang, Maria, Riley, Mariko, Delker, Silvia L, Ito, Takumi, Ando, Hideki, Mori, Tomoyuki, Hirano, Yoshinori, Handa, Hiroshi, Hakoshima, Toshio, Daniel, Thomas O, Cathers, Brian E
Published in Nature structural & molecular biology (01.09.2014)
Published in Nature structural & molecular biology (01.09.2014)
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Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy
Chen, Qing, Xie, Weilin, Kuhn, Deborah J., Voorhees, Peter M., Lopez-Girona, Antonia, Mendy, Derek, Corral, Laura G., Krenitsky, Veronique Plantevin, Xu, Weiming, Moutouh-de Parseval, Laure, Webb, David R., Mercurio, Frank, Nakayama, Keiichi I., Nakayama, Keiko, Orlowski, Robert Z.
Published in Blood (01.05.2008)
Published in Blood (01.05.2008)
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Journal Article
Lenalidomide inhibits the proliferation of CLL cells via a cereblon/p21(WAF1/Cip1)-dependent mechanism independent of functional p53
Fecteau, Jessie-F, Corral, Laura G, Ghia, Emanuela M, Gaidarova, Svetlana, Futalan, Diahnn, Bharati, Ila Sri, Cathers, Brian, Schwaederlé, Maria, Cui, Bing, Lopez-Girona, Antonia, Messmer, Davorka, Kipps, Thomas J
Published in Blood (04.09.2014)
Published in Blood (04.09.2014)
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Journal Article
Lenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cells
VERHELLE, Dominique, CORRAL, Laura G, LOPEZ-GIRONA, Antonia, MUTTER, George W, BRADY, Helen A, CHAN, Kyle W. H, WONG, Kevin, MUELLER, Jessica H, MOUTOUH-DE PARSEVAL, Laure, JENSEN-PERGAKES, Kristen, SCHAFER, Peter H, CHEN, Roger, GLEZER, Emilia, FERGUSON, Gregory D
Published in Cancer research (Chicago, Ill.) (15.01.2007)
Published in Cancer research (Chicago, Ill.) (15.01.2007)
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Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-α Inhibitor
Man, Hon-Wah, Schafer, Peter, Wong, Lu Min, Patterson, Rebecca T, Corral, Laura G, Raymon, Heather, Blease, Kate, Leisten, Jim, Shirley, Michael A, Tang, Yang, Babusis, Darius M, Chen, Roger, Stirling, Dave, Muller, George W
Published in Journal of medicinal chemistry (26.03.2009)
Published in Journal of medicinal chemistry (26.03.2009)
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Journal Article
Discovery of (S)-N-{2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl}acetamide (Apremilast), a Potent and Orally Active Phosphodiesterase 4 and Tumor Necrosis Factor-a Inhibitor
MAN, Hon-Wah, SCHAFER, Peter, BABUSIS, Darius M, CHEN, Roger, STIRLING, Dave, MULLER, George W, LU MIN WONG, PATTERSON, Rebecca T, CORRAL, Laura G, RAYMON, Heather, BLEASE, Kate, LEISTEN, Jim, SHIRLEY, Michael A, YANG TANG
Published in Journal of medicinal chemistry (26.03.2009)
Published in Journal of medicinal chemistry (26.03.2009)
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Journal Article
Immunomodulatory drugs reorganize cytoskeleton by modulating Rho GTPases
Xu, Yibing, Li, Jianwu, Ferguson, Gregory D., Mercurio, Frank, Khambatta, Gody, Morrison, Lisa, Lopez-Girona, Antonia, Corral, Laura G., Webb, David R., Bennett, Brydon L., Xie, Weilin
Published in Blood (09.07.2009)
Published in Blood (09.07.2009)
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Journal Article
Pomalidomide and lenalidomide regulate erythropoiesis and fetal hemoglobin production in human CD34+ cells
Moutouh-de Parseval, Laure A, Verhelle, Dominique, Glezer, Emilia, Jensen-Pergakes, Kristen, Ferguson, Gregory D, Corral, Laura G, Morris, Christopher L, Muller, George, Brady, Helen, Chan, Kyle
Published in The Journal of clinical investigation (01.01.2008)
Published in The Journal of clinical investigation (01.01.2008)
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Journal Article
A novel fibroblast activation inhibitor attenuates left ventricular remodeling and preserves cardiac function in heart failure
Bradley, Jessica M, Spaletra, Pablo, Li, Zhen, Sharp, 3rd, Thomas E, Goodchild, Traci T, Corral, Laura G, Fung, Leah, Chan, Kyle W H, Sullivan, Robert W, Swindlehurst, Cathy A, Lefer, David J
Published in American journal of physiology. Heart and circulatory physiology (01.09.2018)
Published in American journal of physiology. Heart and circulatory physiology (01.09.2018)
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Journal Article
Ceftaroline fosamil: clinical experience after 23-month prescription in a tertiary hospital
Alonso Álvarez, A, Ramos Merino, L, Castelo Corral, L M, Padín Trigo, A, Sousa Regueiro, D, Míguez Rey, E, Sánchez Vidal, E
Published in Revista española de quimioterapia (01.04.2021)
Published in Revista española de quimioterapia (01.04.2021)
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Pomalidomide augments fetal hemoglobin production without the myelosuppressive effects of hydroxyurea in transgenic sickle cell mice
Meiler, Steffen E., Wade, Marlene, Kutlar, Ferdane, Yerigenahally, Shobha D., Xue, Yongjun, Moutouh-de Parseval, Laure A., Corral, Laura G., Swerdlow, Paul S., Kutlar, Abdullah
Published in Blood (28.07.2011)
Published in Blood (28.07.2011)
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Journal Article
B7-H4 is a novel membrane-bound protein and a candidate serum and tissue biomarker for ovarian cancer
SIMON, Iris, SHAOQIU ZHUO, CORRAL, Laura, DIAMANDIS, Eleftherios P, SARNO, Mark J, WOLFERT, Robert L, KIM, Nam W
Published in Cancer research (Chicago, Ill.) (01.02.2006)
Published in Cancer research (Chicago, Ill.) (01.02.2006)
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Journal Article
Compounded Melatonin Cream for the Prevention and Treatment of Radiation Dermatitis: A Case Report
Garcia-Segura, Laura Corral, Garcia-Segura, Javier Corral, Delgado, Dorado Carlos, Romero, Maldonaldo Nuria, Salgado, Elena Cardero, Llorens, Lucía Pérez
Published in International journal of pharmaceutical compounding (01.01.2022)
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Published in International journal of pharmaceutical compounding (01.01.2022)
Journal Article
Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity
Ruchelman, Alexander L., Man, Hon-Wah, Zhang, Weihong, Chen, Roger, Capone, Lori, Kang, Jian, Parton, Anastasia, Corral, Laura, Schafer, Peter H., Babusis, Darius, Moghaddam, Mehran F., Tang, Yang, Shirley, Michael A., Muller, George W.
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
Published in Bioorganic & medicinal chemistry letters (01.01.2013)
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Nosocomial meningitis caused by ESBL- and OXA-48-producing Klebsiella pneumoniae and treated with ceftazidime-avibactam. Report of one case and review of the literature
Valiente De Santis, L B, Márquez Gómez, I, Sobrino Díaz, B, Pérez Camacho, I, Mediavilla Gradolph, C, Caballero Martínez, L F, Vicente Hernández, F J, Castelo Corral, L, Delgado Fernández, M, Plata Ciézar, A, Ruiz Mesa, J D, Reguera Iglesias, J M
Published in Revista española de quimioterapia (01.12.2022)
Published in Revista española de quimioterapia (01.12.2022)
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Journal Article
Enhancement of Cytokine Production and AP-1 Transcriptional Activity in T Cells by Thalidomide-Related Immunomodulatory Drugs
Schafer, Peter H, Gandhi, Anita K, Loveland, Michelle A, Chen, Roger S, Man, Hon-Wah, Schnetkamp, Paul P M, Wolbring, Gregor, Govinda, Sowmya, Corral, Laura G, Payvandi, Faribourz, Muller, George W, Stirling, David I
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
Published in The Journal of pharmacology and experimental therapeutics (01.06.2003)
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Journal Article
Dalbavancin as suppressive antibiotic therapy in patients with prosthetic infections: efficacy and safety
Ruiz-Sancho, Andrés, Núñez-Núñez, María, Castelo-Corral, Laura, Martínez-Marcos, Francisco Javier, Lois-Martínez, Nagore, Abdul-Aziz, Mohd Hafiz, Vinuesa-García, David
Published in Frontiers in pharmacology (28.06.2023)
Published in Frontiers in pharmacology (28.06.2023)
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