Activation of STING requires palmitoylation at the Golgi
Mukai, Kojiro, Konno, Hiroyasu, Akiba, Tatsuya, Uemura, Takefumi, Waguri, Satoshi, Kobayashi, Toshihide, Barber, Glen N., Arai, Hiroyuki, Taguchi, Tomohiko
Published in Nature communications (21.06.2016)
Published in Nature communications (21.06.2016)
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Journal Article
Homeostatic regulation of STING by retrograde membrane traffic to the ER
Mukai, Kojiro, Ogawa, Emari, Uematsu, Rei, Kuchitsu, Yoshihiko, Kiku, Fumika, Uemura, Takefumi, Waguri, Satoshi, Suzuki, Takehiro, Dohmae, Naoshi, Arai, Hiroyuki, Shum, Anthony K., Taguchi, Tomohiko
Published in Nature communications (04.01.2021)
Published in Nature communications (04.01.2021)
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Journal Article
STING Operation at the ER/Golgi Interface
Taguchi, Tomohiko, Mukai, Kojiro, Takaya, Eiko, Shindo, Ruri
Published in Frontiers in immunology (03.05.2021)
Published in Frontiers in immunology (03.05.2021)
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Journal Article
Specific association of TBK1 with the trans-Golgi network following STING stimulation
Kemmoku, Haruka, Kuchitsu, Yoshihiko, Mukai, Kojiro, Taguchi, Tomohiko
Published in Cell Structure and Function (01.01.2022)
Published in Cell Structure and Function (01.01.2022)
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Journal Article
A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome
Deng, Zimu, Chong, Zhenlu, Law, Christopher S, Mukai, Kojiro, Ho, Frances O, Martinu, Tereza, Backes, Bradley J, Eckalbar, Walter L, Taguchi, Tomohiko, Shum, Anthony K
Published in The Journal of experimental medicine (02.11.2020)
Published in The Journal of experimental medicine (02.11.2020)
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Journal Article
PI4P/PS countertransport by ORP10 at ER-endosome membrane contact sites regulates endosome fission
Kawasaki, Asami, Sakai, Akiko, Nakanishi, Hiroki, Hasegawa, Junya, Taguchi, Tomohiko, Sasaki, Junko, Arai, Hiroyuki, Sasaki, Takehiko, Igarashi, Michihiro, Nakatsu, Fubito
Published in The Journal of cell biology (03.01.2022)
Published in The Journal of cell biology (03.01.2022)
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Journal Article
Development of a Series of Practical Fluorescent Chemical Tools To Measure pH Values in Living Samples
Takahashi, Shodai, Kagami, Yu, Hanaoka, Kenjiro, Terai, Takuya, Komatsu, Toru, Ueno, Tasuku, Uchiyama, Masanobu, Koyama-Honda, Ikuko, Mizushima, Noboru, Taguchi, Tomohiko, Arai, Hiroyuki, Nagano, Tetsuo, Urano, Yasuteru
Published in Journal of the American Chemical Society (09.05.2018)
Published in Journal of the American Chemical Society (09.05.2018)
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Journal Article
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling
Hansen, Anne Louise, Buchan, Gregory J., Rühl, Michael, Mukai, Kojiro, Salvatore, Sonia R., Ogawa, Emari, Andersen, Sidsel D., Iversen, Marie B., Thielke, Anne L., Gunderstofte, Camilla, Motwani, Mona, Møller, Charlotte T., Jakobsen, Andreas S., Fitzgerald, Katherine A., Roos, Jessica, Lin, Rongtuan, Maier, Thorsten J., Goldbach-Mansky, Raphaela, Miner, Cathrine A., Qian, Wei, Miner, Jonathan J., Rigby, Rachel E., Rehwinkel, Jan, Jakobsen, Martin R., Arai, Hiroyuki, Taguchi, Tomohiko, Schopfer, Francisco J., Olagnier, David, Holm, Christian K.
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (14.08.2018)
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Journal Article
Cullin‐3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2‐positive breast cancer cells
Murakami, Akari, Maekawa, Masashi, Kawai, Katsuhisa, Nakayama, Jun, Araki, Nobukazu, Semba, Kentaro, Taguchi, Tomohiko, Kamei, Yoshiaki, Takada, Yasutsugu, Higashiyama, Shigeki
Published in Cancer science (01.02.2019)
Published in Cancer science (01.02.2019)
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Journal Article
A cell-free assay implicates a role of sphingomyelin and cholesterol in STING phosphorylation
Takahashi, Kanoko, Niki, Takahiro, Ogawa, Emari, Fumika, Kiku, Nishioka, Yu, Sawa, Masaaki, Arai, Hiroyuki, Mukai, Kojiro, Taguchi, Tomohiko
Published in Scientific reports (07.06.2021)
Published in Scientific reports (07.06.2021)
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Journal Article
Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution
Tsuji, Takuma, Cheng, Jinglei, Tatematsu, Tsuyako, Ebata, Aoi, Kamikawa, Hiroki, Fujita, Akikazu, Gyobu, Sayuri, Segawa, Katsumori, Arai, Hiroyuki, Taguchi, Tomohiko, Nagata, Shigekazu, Fujimoto, Toyoshi
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2019)
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Journal Article
STING palmitoylation as a therapeutic target
Hansen, Anne Louise, Mukai, Kojiro, Schopfer, Francisco J., Taguchi, Tomohiko, Holm, Christian K.
Published in Cellular & molecular immunology (01.03.2019)
Published in Cellular & molecular immunology (01.03.2019)
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Journal Article
Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase
Lee, Shoken, Uchida, Yasunori, Wang, Jiao, Matsudaira, Tatsuyuki, Nakagawa, Takatoshi, Kishimoto, Takuma, Mukai, Kojiro, Inaba, Takehiko, Kobayashi, Toshihide, Molday, Robert S, Taguchi, Tomohiko, Arai, Hiroyuki
Published in The EMBO journal (04.03.2015)
Published in The EMBO journal (04.03.2015)
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Journal Article
The binding of TBK1 to STING requires exocytic membrane traffic from the ER
Ogawa, Emari, Mukai, Kojiro, Saito, Kota, Arai, Hiroyuki, Taguchi, Tomohiko
Published in Biochemical and biophysical research communications (03.09.2018)
Published in Biochemical and biophysical research communications (03.09.2018)
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Journal Article
Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis
Maekawa, Masashi, Terasaka, Shimpei, Mochizuki, Yasuhiro, Kawai, Katsuhisa, Ikeda, Yuka, Araki, Nobukazu, Skolnik, Edward Y., Taguchi, Tomohiko, Arai, Hiroyuki
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.03.2014)
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Journal Article
SLC15A4 mediates M1-prone metabolic shifts in macrophages and guards immune cells from metabolic stress
Kobayashi, Toshihiko, Nguyen-Tien, Dat, Sorimachi, Yuriko, Sugiura, Yuki, Suzuki, Takehiro, Karyu, Hitomi, Shimabukuro-Demoto, Shiho, Uemura, Tatsuki, Okamura, Tadashi, Taguchi, Tomohiko, Ueki, Kohjiro, Kato, Norihiro, Goda, Nobuhito, Dohmae, Naoshi, Takubo, Keiyo, Suematsu, Makoto, Toyama-Sorimachi, Noriko
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (17.08.2021)
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Journal Article
PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation
Inoue, Chiaki, Mukai, Kojiro, Matsudaira, Tatsuyuki, Nakayama, Jun, Kono, Nozomu, Aoki, Junken, Arai, Hiroyuki, Uchida, Yasunori, Taguchi, Tomohiko
Published in Scientific reports (13.11.2023)
Published in Scientific reports (13.11.2023)
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