Seeking the Elusive Long-Acting Ozonide: Discovery of Artefenomel (OZ439)
Kim, Ho Shin, Hammill, Jared T, Guy, R. Kiplin
Published in Journal of medicinal chemistry (13.04.2017)
Published in Journal of medicinal chemistry (13.04.2017)
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Journal Article
Discovery of Novel Pyrazolo-pyridone DCN1 Inhibitors Controlling Cullin Neddylation
Kim, Ho Shin, Hammill, Jared T, Scott, Daniel C, Chen, Yizhe, Min, Jaeki, Rector, Jonah, Singh, Bhuvanesh, Schulman, Brenda A, Guy, R. Kiplin
Published in Journal of medicinal chemistry (26.09.2019)
Published in Journal of medicinal chemistry (26.09.2019)
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Journal Article
Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation
Hammill, Jared T, Bhasin, Deepak, Scott, Daniel C, Min, Jaeki, Chen, Yizhe, Lu, Yan, Yang, Lei, Kim, Ho Shin, Connelly, Michele C, Hammill, Courtney, Holbrook, Gloria, Jeffries, Cynthia, Singh, Bhuvanesh, Schulman, Brenda A, Guy, R. Kiplin
Published in Journal of medicinal chemistry (12.04.2018)
Published in Journal of medicinal chemistry (12.04.2018)
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Journal Article
Improvement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M
Kim, Ho Shin, Hammill, Jared T., Scott, Daniel C., Chen, Yizhe, Rice, Amy L., Pistel, William, Singh, Bhuvanesh, Schulman, Brenda A., Guy, R. Kiplin
Published in Journal of medicinal chemistry (13.05.2021)
Published in Journal of medicinal chemistry (13.05.2021)
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Journal Article
Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase
Scott, Daniel C, Hammill, Jared T, Min, Jaeki, Rhee, David Y, Connelly, Michele, Sviderskiy, Vladislav O, Bhasin, Deepak, Chen, Yizhe, Ong, Su-Sien, Chai, Sergio C, Goktug, Asli N, Huang, Guochang, Monda, Julie K, Low, Jonathan, Kim, Ho Shin, Paulo, Joao A, Cannon, Joe R, Shelat, Anang A, Chen, Taosheng, Kelsall, Ian R, Alpi, Arno F, Pagala, Vishwajeeth, Wang, Xusheng, Peng, Junmin, Singh, Bhuvanesh, Harper, J Wade, Schulman, Brenda A, Guy, R Kip
Published in Nature chemical biology (01.08.2017)
Published in Nature chemical biology (01.08.2017)
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Journal Article
Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides
Kim, Ho Shin, Ortiz, Diana, Kadayat, Tara Man, Fargo, Corinne M., Hammill, Jared T., Chen, Yizhe, Rice, Amy L., Begley, Kristin L., Shoeran, Gaurav, Pistel, William, Yates, Phillip A., Sanchez, Marco A., Landfear, Scott M., Guy, R. Kiplin
Published in Journal of medicinal chemistry (08.06.2023)
Published in Journal of medicinal chemistry (08.06.2023)
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Journal Article
Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation
Hammill, Jared T, Scott, Daniel C, Min, Jaeki, Connelly, Michele C, Holbrook, Gloria, Zhu, Fangyi, Matheny, Amy, Yang, Lei, Singh, Bhuvanesh, Schulman, Brenda A, Guy, R. Kiplin
Published in Journal of medicinal chemistry (12.04.2018)
Published in Journal of medicinal chemistry (12.04.2018)
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Journal Article
Amino-Substituted 3-Aryl- and 3-Heteroarylquinolines as Potential Antileishmanial Agents
Hammill, Jared T., Sviripa, Vitaliy M., Kril, Liliia M., Ortiz, Diana, Fargo, Corinne M., Kim, Ho Shin, Chen, Yizhe, Rector, Jonah, Rice, Amy L., Domagalska, Malgorzata A., Begley, Kristin L., Liu, Chunming, Rangnekar, Vivek M., Dujardin, Jean-Claude, Watt, David S., Landfear, Scott M., Guy, R. Kiplin
Published in Journal of medicinal chemistry (26.08.2021)
Published in Journal of medicinal chemistry (26.08.2021)
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Journal Article
Antimalarial activity of tetrahydro-β-carbolines targeting the ATP binding pocket of the Plasmodium falciparum heat shock 90 protein
Eagon, Scott, Hammill, Jared T., Bach, Jordan, Everson, Nikalet, Sisley, Tyler A., Walls, Michael J., Durham, Sierra, Pillai, Dylan R., Falade, Mofolusho O., Rice, Amy L., Kimball, Joshua J., Lazaro, Horacio, DiBernardo, Celine, Kiplin Guy, R.
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
Published in Bioorganic & medicinal chemistry letters (01.11.2020)
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Journal Article
Antimalarial activity of 2,6-dibenzylidenecyclohexanone derivatives
Eagon, Scott, Hammill, Jared T., Fitzsimmons, Kasey, Sienko, Natalie, Nguyen, Brandon, Law, Jarvis, Manjunath, Aashrita, Wilkinson, Steven P., Thompson, Kara, Glidden, Julia Elizabeth, Rice, Amy L., Falade, Mofolusho O., Kimball, Joshua J., DiBernardo, Celine, Guy, R. Kiplin
Published in Bioorganic & medicinal chemistry letters (01.09.2021)
Published in Bioorganic & medicinal chemistry letters (01.09.2021)
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Journal Article
Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening
Ortiz, Diana, Guiguemde, W Armand, Hammill, Jared T, Carrillo, Angela K, Chen, Yizhe, Connelly, Michele, Stalheim, Kayla, Elya, Carolyn, Johnson, Alex, Min, Jaeki, Shelat, Anang, Smithson, David C, Yang, Lei, Zhu, Fangyi, Guy, R Kiplin, Landfear, Scott M
Published in PLoS neglected tropical diseases (01.12.2017)
Published in PLoS neglected tropical diseases (01.12.2017)
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Journal Article
Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones
Chen, Yizhe, Zhu, Fangyi, Hammill, Jared, Holbrook, Gloria, Yang, Lei, Freeman, Burgess, White, Karen L, Shackleford, David M, O'Loughlin, Kathleen G, Charman, Susan A, Mirsalis, Jon C, Guy, R Kiplin
Published in Malaria journal (19.02.2021)
Published in Malaria journal (19.02.2021)
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Journal Article
Combining SJ733, an oral ATP4 inhibitor of Plasmodium falciparum, with the pharmacokinetic enhancer cobicistat: An innovative approach in antimalarial drug development
Gaur, Aditya H., Panetta, John C., Smith, Amber M., Dallas, Ronald H., Freeman, Burgess B., Stewart, Tracy B., Tang, Li, John, Elizabeth, Branum, Kristen C., Patel, Nehali D., Ost, Shelley, Heine, Ryan N., Richardson, Julie L., Hammill, Jared T., Bebrevska, Lidiya, Gusovsky, Fabian, Maki, Noritsugu, Yanagi, Toshiharu, Flynn, Patricia M., McCarthy, James S., Chalon, Stephan, Guy, R. Kiplin
Published in EBioMedicine (01.06.2022)
Published in EBioMedicine (01.06.2022)
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Journal Article
Iterative structure-based peptide-like inhibitor design against the botulinum neurotoxin serotype A
Zuniga, Jorge E, Hammill, Jared T, Drory, Omri, Nuss, Jonathan E, Burnett, James C, Gussio, Rick, Wipf, Peter, Bavari, Sina, Brunger, Axel T
Published in PloS one (30.06.2010)
Published in PloS one (30.06.2010)
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Journal Article
Synthesis and chemical diversity analysis of bicyclo[3.3.1]non-3-en-2-ones
Hammill, Jared T., Contreras-García, Julia, Virshup, Aaron M., Beratan, David N., Yang, Weitao, Wipf, Peter
Published in Tetrahedron (31.03.2010)
Published in Tetrahedron (31.03.2010)
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Journal Article
DCN1/2-매개된 큐린 네딜화의 약학적 활성 피라졸로-피리돈 조절제
HAMMILL JARED T, SCOTT DANIEL CHARLES, SINGH BHUVANESH, GUY RODNEY KIPLIN, SCHULMAN BENDA ARLENE, KIM HOSHIN
Year of Publication 08.04.2022
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Year of Publication 08.04.2022
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