Improving the secretory capacity of Chinese hamster ovary cells by ectopic expression of effector genes: Lessons learned and future directions
Hansen, Henning Gram, Pristovšek, Nuša, Kildegaard, Helene Faustrup, Lee, Gyun Min
Published in Biotechnology advances (01.01.2017)
Published in Biotechnology advances (01.01.2017)
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Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
Gutierrez, Jahir M., Feizi, Amir, Li, Shangzhong, Kallehauge, Thomas B., Hefzi, Hooman, Grav, Lise M., Ley, Daniel, Baycin Hizal, Deniz, Betenbaugh, Michael J., Voldborg, Bjorn, Faustrup Kildegaard, Helene, Min Lee, Gyun, Palsson, Bernhard O., Nielsen, Jens, Lewis, Nathan E.
Published in Nature communications (02.01.2020)
Published in Nature communications (02.01.2020)
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Multiplex secretome engineering enhances recombinant protein production and purity
Kol, Stefan, Ley, Daniel, Wulff, Tune, Decker, Marianne, Arnsdorf, Johnny, Schoffelen, Sanne, Hansen, Anders Holmgaard, Jensen, Tanja Lyholm, Gutierrez, Jahir M., Chiang, Austin W. T., Masson, Helen O., Palsson, Bernhard O., Voldborg, Bjørn G., Pedersen, Lasse Ebdrup, Kildegaard, Helene Faustrup, Lee, Gyun Min, Lewis, Nathan E.
Published in Nature communications (20.04.2020)
Published in Nature communications (20.04.2020)
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Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells
Hong, Jong Kwang, Lee, Sang Min, Kim, Kyung-Yong, Lee, Gyun Min
Published in Applied microbiology and biotechnology (01.06.2014)
Published in Applied microbiology and biotechnology (01.06.2014)
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Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage
Koh, Young Jun, Kim, Hak-Zoo, Hwang, Seong-Ik, Lee, Jeung Eun, Oh, Nuri, Jung, Keehoon, Kim, Minah, Kim, Kyung Eun, Kim, Homin, Lim, Nam-Kyu, Jeon, Choon-Ju, Lee, Gyun Min, Jeon, Byeong Hwa, Nam, Do-Hyun, Sung, Hoon Ki, Nagy, Andras, Yoo, Ook Joon, Koh, Gou Young
Published in Cancer cell (09.08.2010)
Published in Cancer cell (09.08.2010)
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An optimized genome-wide, virus-free CRISPR screen for mammalian cells
Xiong, Kai, la Cour Karottki, Karen Julie, Hefzi, Hooman, Li, Songyuan, Grav, Lise Marie, Li, Shangzhong, Spahn, Philipp, Lee, Jae Seong, Ventina, Ildze, Lee, Gyun Min, Lewis, Nathan E., Kildegaard, Helene Faustrup, Pedersen, Lasse Ebdrup
Published in Cell reports methods (23.08.2021)
Published in Cell reports methods (23.08.2021)
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Effect of doxycycline-regulated protein disulfide isomerase expression on the specific productivity of recombinant CHO cells: Thrombopoietin and antibody
Mohan, Chaya, Park, Soon Hye, Chung, Joo Young, Lee, Gyun Min
Published in Biotechnology and bioengineering (15.10.2007)
Published in Biotechnology and bioengineering (15.10.2007)
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COMP-Ang1: A Designed Angiopoietin-1 Variant with Nonleaky Angiogenic Activity
Cho, Chung-Hyun, Kammerer, Richard A., Lee, Hyuek Jong, Steinmetz, Michel O., Ryu, Young Shin, Lee, Sung Ho, Yasunaga, Kunio, Kim, Kyung-Tae, Kim, Injune, Choi, Han-Ho, Kim, Won, Kim, Sung Hyun, Park, Sung Kwang, Lee, Gyun Min, Koh, Gou Young, Olson, Eric N.
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (13.04.2004)
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A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells
Shamie, Isaac, Duttke, Sascha H, Karottki, Karen J la Cour, Han, Claudia Z, Hansen, Anders H, Hefzi, Hooman, Xiong, Kai, Li, Shangzhong, Roth, Samuel J, Tao, Jenhan, Lee, Gyun Min, Glass, Christopher K, Kildegaard, Helene Faustrup, Benner, Christopher, Lewis, Nathan E
Published in NAR genomics and bioinformatics (01.09.2021)
Published in NAR genomics and bioinformatics (01.09.2021)
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Oligomerization and Multimerization Are Critical for Angiopoietin-1 to Bind and Phosphorylate Tie2
Kim, Kyung-Tae, Choi, Han-Ho, Steinmetz, Michel O., Maco, Bohumil, Kammerer, Richard A., Ahn, So Young, Kim, Hak-Zoo, Lee, Gyun Min, Koh, Gou Young
Published in The Journal of biological chemistry (20.05.2005)
Published in The Journal of biological chemistry (20.05.2005)
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Bcl-xL overexpression does not enhance specific erythropoietin productivity of recombinant CHO cells grown at 33°C and 37°C
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Conference Proceeding
Angiopoietin-2 Exocytosis Is Stimulated by Sphingosine-1-Phosphate in Human Blood and Lymphatic Endothelial Cells
JANG, Cholsoon, YOUNG JUN KOH, NAM KYU LIM, HYUN JUNG KANG, DUK HOON KIM, SUNG KWANG PARK, GYUN MIN LEE, CHOON JU JEON, GOU YOUNG KOH
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2009)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.03.2009)
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Long-Term and Sustained COMP-Ang1 Induces Long-Lasting Vascular Enlargement and Enhanced Blood Flow
Cho, Chung-Hyun, Kim, Kyung Eun, Byun, Jonghoe, Jang, Hyung-Suk, Kim, Duk-Kyung, Baluk, Peter, Baffert, Fabienne, Lee, Gyun Min, Mochizuki, Naoki, Kim, Jin, Jeon, Byeong Hwa, McDonald, Donald M, Koh, Gou Young
Published in Circulation research (08.07.2005)
Published in Circulation research (08.07.2005)
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