EPCR expression marks UM171-expanded CD34+ cord blood stem cells
Fares, Iman, Chagraoui, Jalila, Lehnertz, Bernhard, MacRae, Tara, Mayotte, Nadine, Tomellini, Elisa, Aubert, Léo, Roux, Philippe P., Sauvageau, Guy
Published in Blood (22.06.2017)
Published in Blood (22.06.2017)
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Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia
Baccelli, Irène, Gareau, Yves, Lehnertz, Bernhard, Gingras, Stéphane, Spinella, Jean-François, Corneau, Sophie, Mayotte, Nadine, Girard, Simon, Frechette, Mélanie, Blouin-Chagnon, Valérie, Leveillé, Koryne, Boivin, Isabel, MacRae, Tara, Krosl, Jana, Thiollier, Clarisse, Lavallée, Vincent-Philippe, Kanshin, Evgeny, Bertomeu, Thierry, Coulombe-Huntington, Jasmin, St-Denis, Corinne, Bordeleau, Marie-Eve, Boucher, Geneviève, Roux, Philippe P., Lemieux, Sébastien, Tyers, Mike, Thibault, Pierre, Hébert, Josée, Marinier, Anne, Sauvageau, Guy
Published in Cancer cell (08.07.2019)
Published in Cancer cell (08.07.2019)
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Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
Fares, Iman, Chagraoui, Jalila, Gareau, Yves, Gingras, Stéphane, Ruel, Réjean, Mayotte, Nadine, Csaszar, Elizabeth, Knapp, David J. H. F., Miller, Paul, Ngom, Mor, Imren, Suzan, Roy, Denis-Claude, Watts, Kori L., Kiem, Hans-Peter, Herrington, Robert, Iscove, Norman N., Humphries, R. Keith, Eaves, Connie J., Cohen, Sandra, Marinier, Anne, Zandstra, Peter W., Sauvageau, Guy
Published in Science (American Association for the Advancement of Science) (19.09.2014)
Published in Science (American Association for the Advancement of Science) (19.09.2014)
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Journal Article
UM171 induces a homeostatic inflammatory-detoxification response supporting human HSC self-renewal
Chagraoui, Jalila, Lehnertz, Bernhard, Girard, Simon, Spinella, Jean Francois, Fares, Iman, Tomellini, Elisa, Mayotte, Nadine, Corneau, Sophie, MacRae, Tara, Simon, Laura, Sauvageau, Guy
Published in PloS one (08.11.2019)
Published in PloS one (08.11.2019)
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Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors
Lavallée, Vincent-Philippe, Krosl, Jana, Lemieux, Sébastien, Boucher, Geneviève, Gendron, Patrick, Pabst, Caroline, Boivin, Isabel, Marinier, Anne, Guidos, Cynthia J., Meloche, Sylvain, Hébert, Josée, Sauvageau, Guy
Published in Blood (16.06.2016)
Published in Blood (16.06.2016)
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Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance
Buscarlet, Manuel, Krasteva, Veneta, Ho, Lena, Simon, Camille, Hébert, Josée, Wilhelm, Brian, Crabtree, Gerald R., Sauvageau, Guy, Thibault, Pierre, Lessard, Julie A.
Published in Blood (13.03.2014)
Published in Blood (13.03.2014)
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Journal Article
EVI1-rearranged acute myeloid leukemias are characterized by distinct molecular alterations
Lavallée, Vincent-Philippe, Gendron, Patrick, Lemieux, Sébastien, D’Angelo, Giovanni, Hébert, Josée, Sauvageau, Guy
Published in Blood (01.01.2015)
Published in Blood (01.01.2015)
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Cut-like homeobox 1 (CUX1) tumor suppressor gene haploinsufficiency induces apoptosis evasion to sustain myeloid leukemia
Supper, Emmanuelle, Rudat, Saskia, Iyer, Vivek, Droop, Alastair, Wong, Kim, Spinella, Jean-François, Thomas, Patrick, Sauvageau, Guy, Adams, David J., Wong, Chi C.
Published in Nature communications (30.04.2021)
Published in Nature communications (30.04.2021)
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Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
Rouette, Alexandre, Trofimov, Assya, Haberl, David, Boucher, Geneviève, Lavallée, Vincent-Philippe, D’Angelo, Giovanni, Hébert, Josée, Sauvageau, Guy, Lemieux, Sébastien, Perreault, Claude
Published in Scientific reports (23.09.2016)
Published in Scientific reports (23.09.2016)
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The methyltransferase G9a regulates HoxA9-dependent transcription in AML
Lehnertz, Bernhard, Pabst, Caroline, Su, Le, Miller, Michelle, Liu, Feng, Yi, Lin, Zhang, Regan, Krosl, Jana, Yung, Eric, Kirschner, Jeanette, Rosten, Patty, Underhill, T Michael, Jin, Jian, Hébert, Josée, Sauvageau, Guy, Humphries, R Keith, Rossi, Fabio M
Published in Genes & development (15.02.2014)
Published in Genes & development (15.02.2014)
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A genetic screen in Drosophila uncovers the multifaceted properties of the NUP98-HOXA9 oncogene
Gavory, Gwenaëlle, Baril, Caroline, Laberge, Gino, Bidla, Gawa, Koonpaew, Surapong, Sonea, Thomas, Sauvageau, Guy, Therrien, Marc
Published in PLoS genetics (12.08.2021)
Published in PLoS genetics (12.08.2021)
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RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature
Lavallée, Vincent-Philippe, Lemieux, Sébastien, Boucher, Geneviève, Gendron, Patrick, Boivin, Isabel, Armstrong, Richard N., Sauvageau, Guy, Hébert, Josée
Published in Blood (19.05.2016)
Published in Blood (19.05.2016)
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Legal and Ethical Considerations for the Design and Use of Web Portals for Researchers, Clinicians, and Patients: Scoping Literature Review
Lang, Michael, Lemieux, Sébastien, Hébert, Josée, Sauvageau, Guy, Zawati, Ma'n H
Published in Journal of medical Internet research (11.11.2021)
Published in Journal of medical Internet research (11.11.2021)
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A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2
Dubois, Emilie L, Guitton-Sert, Laure, Béliveau, Mariline, Parmar, Kalindi, Chagraoui, Jalila, Vignard, Julien, Pauty, Joris, Caron, Marie-Christine, Coulombe, Yan, Buisson, Rémi, Jacquet, Karine, Gamblin, Clémence, Gao, Yuandi, Laprise, Patrick, Lebel, Michel, Sauvageau, Guy, D. d’Andrea, Alan, Masson, Jean-Yves
Published in Nucleic acids research (22.08.2019)
Published in Nucleic acids research (22.08.2019)
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Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML
Garg, Swati, Reyes-Palomares, Armando, He, Lixiazi, Bergeron, Anne, Lavallée, Vincent-Philippe, Lemieux, Sébastien, Gendron, Patrick, Rohde, Christian, Xia, Jianglong, Jagdhane, Prarabdha, Müller-Tidow, Carsten, Lipka, Daniel B., Imren, Suzan, Humphries, R. Keith, Waskow, Claudia, Vick, Binje, Jeremias, Irmela, Richard-Carpentier, Guillaume, Hébert, Josée, Sauvageau, Guy, Zaugg, Judith B., Barabé, Frédéric, Pabst, Caroline
Published in Blood (18.07.2019)
Published in Blood (18.07.2019)
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anticlastogenic function for the Polycomb Group gene Bmi1
Chagraoui, Jalila, Hébert, Josée, Girard, Simon, Sauvageau, Guy
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2011)
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An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity
Hope, Kristin J., Cellot, Sonia, Ting, Stephen B., MacRae, Tara, Mayotte, Nadine, Iscove, Norman N., Sauvageau, Guy
Published in Cell stem cell (02.07.2010)
Published in Cell stem cell (02.07.2010)
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SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells
Gerby, Bastien, Tremblay, Cedric S, Tremblay, Mathieu, Rojas-Sutterlin, Shanti, Herblot, Sabine, Hébert, Josée, Sauvageau, Guy, Lemieux, Sébastien, Lécuyer, Eric, Veiga, Diogo F T, Hoang, Trang
Published in PLoS genetics (01.12.2014)
Published in PLoS genetics (01.12.2014)
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