Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia
Liu, Ping, Wang, Liping, DuBois, Byron G, Colandrea, Vincent J, Liu, Rongqiang, Cai, Jiaqiang, Du, Xiaoxing, Quan, Weiguo, Morris, William, Bai, Jianwu, Bishwokarma, Bimjhana, Cheng, Mangeng, Piesvaux, Jennifer, Ray, Kallol, Alpert, Carla, Chiu, Chi-Sung, Zielstorff, Mark, Metzger, Joseph M, Yang, Liming, Leung, Dennis, Alleyne, Candice, Vincent, Stella H, Pucci, Vincenzo, Li, Xiaofang, Crespo, Alejandro, Stickens, Dominique, Hale, Jeffrey J, Ujjainwalla, Feroze, Sinz, Christopher J
Published in ACS medicinal chemistry letters (13.12.2018)
Published in ACS medicinal chemistry letters (13.12.2018)
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Journal Article
Design of Potent and Orally Active GPR119 Agonists for the Treatment of Type II Diabetes
Liu, Ping, Hu, Zhiyong, DuBois, Byron G, Moyes, Christopher R, Hunter, David N, Zhu, Cheng, Kar, Nam Fung, Zhu, Yuping, Garfunkle, Joie, Kang, Ling, Chicchi, Gary, Ehrhardt, Anka, Woods, Andrea, Seo, Toru, Woods, Morgan, van Heek, Margaret, Dingley, Karen H, Pang, Jianmei, Salituro, Gino M, Powell, Joyce, Terebetski, Jenna L, Hornak, Viktor, Campeau, Louis-Charles, Lamberson, Joe, Ujjainwalla, Fez, Miller, Michael, Stamford, Andrew, Wood, Harold B, Kowalski, Timothy, Nargund, Ravi P, Edmondson, Scott D
Published in ACS medicinal chemistry letters (13.08.2015)
Published in ACS medicinal chemistry letters (13.08.2015)
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Journal Article
THIAZOLE-SUBSTITUTED AMINOPYRIMIDINES AS SPLEEN TYROSINE KINASE INHIBITORS
WANG, Liping, NORTHRUP, Alan, B, SZEWCZYK, Jason, W, DUBOIS, Byron, ARRINGTON, Kenneth, L, DEBENHAM, John, S, WANG, Ming, LIU, Ping
Year of Publication 14.08.2019
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Year of Publication 14.08.2019
Patent
INHIBITORS OF HIF PROLYL HYDROXYLASE
WANG, Liping, CRESPO, Alejandro, CAI, Jiaqiang, KOTHANDARAMAN, Shankaran, DU, Xiaoxing, DUBOIS, Byron Gabriel, LIU, Rongqiang, QUAN, Weiguo, SINZ, Christopher, GUIADEEN, Deodialsingh, LIU, Ping
Year of Publication 12.02.2020
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Year of Publication 12.02.2020
Patent
ISOQUINOLINE DERIVATIVES AS MGAT2 INHIBITORS
XU, Libo, UJJAINWALLA, Feroze, ZHANG, Rui, BLIZZARD, Timothy A, WANG, Ming, GUO, Zhiqiang, DEBENHAM, John S, GUDE, Candido, XU, Jiayi, CAMPBELL, Brian T, HARPER, Bart, HU, Zhiyong, CHEN, Helen Y, DEWNANI, Sunita V, LIN, Songnian, DUBOIS, Byron, LIU, Ping, BERGER, Richard
Year of Publication 23.12.2020
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Year of Publication 23.12.2020
Patent
Inhibitors of HIF prolyl hydroxylase
Liu, Ping, Wang, Liping, Liu, Rongqiang, Crespo, Alejandro, Dubois, Byron Gabriel, Cai, Jiaqiang, Kothandaraman, Shankaran, Quan, Weiguo, Du, Xiaoxing, Guiadeen, Deodialsingh, Sinz, Christopher
Year of Publication 15.05.2018
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Year of Publication 15.05.2018
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INHIBITORS OF HIF PROLYL HYDROXYLASE
WANG, Liping, CRESPO, Alejandro, CAI, Jiaqiang, KOTHANDARAMAN, Shankaran, DU, Xiaoxing, DUBOIS, Byron Gabriel, LIU, Rongqiang, QUAN, Weiguo, SINZ, Christopher, GUIADEEN, Deodialsingh, LIU, Ping
Year of Publication 21.03.2018
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Year of Publication 21.03.2018
Patent
INHIBITORS OF HIF PROLYL HYDROXYLASE
WANG, Liping, CRESPO, Alejandro, CAI, Jiaqiang, DU, Xiaoxing, DUBOIS, Byron Gabriel, LIU, Rongqiang, QUAN, Weiguo, SINZ, Christopher, LIU, Ping
Year of Publication 28.02.2018
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Year of Publication 28.02.2018
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THIAZOLE-SUBSTITUTED AMINOPYRIMIDINES AS SPLEEN TYROSINE KINASE INHIBITORS
WANG, Liping, NORTHRUP, Alan, B, SZEWCZYK, Jason, W, DUBOIS, Byron, ARRINGTON, Kenneth, L, DEBENHAM, John, S, WANG, Ming, LIU, Ping
Year of Publication 04.01.2017
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Year of Publication 04.01.2017
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Thiazole-substituted aminopyrimidines as spleen tyrosine kinase inhibitors
DuBois Byron, Wang Ming, Wang Liping, Debenham John S, Szewczyk Jason W, Arrington Kenneth L, Northrup Alan B, Liu Ping
Year of Publication 22.11.2016
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Year of Publication 22.11.2016
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INHIBITORS OF HIF PROLYL HYDROXYLASE
LIU RONGQIANG, WANG LIPING, DUBOIS BYRON GABRIEL, GUIADEEN DEODIALSINGH, LIU PING, SINZ CHRISTOPHER, CAI JIAQIANG, CRESPO ALEJANDRO, KOTHANDARAMAN SHANKARAN, DU XIAOXING, QUAN WEIGUO
Year of Publication 17.08.2017
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Year of Publication 17.08.2017
Patent
INHIBITORS OF HIF PROLYL HYDROXYLASE
LIU RONGQIANG, WANG LIPING, DUBOIS BYRON GABRIEL, LIU PING, SINZ CHRISTOPHER, CAI JIAQIANG, CRESPO ALEJANDRO, DU XIAOXING, QUAN WEIGUO
Year of Publication 10.08.2017
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Year of Publication 10.08.2017
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INHIBITORS OF HIF PROLYL HYDROXYLASE
WANG, Liping, CRESPO, Alejandro, CAI, Jiaqiang, DU, Xiaoxing, DUBOIS, Byron Gabriel, LIU, Rongqiang, QUAN, Weiguo, SINZ, Christopher, LIU, Ping
Year of Publication 02.08.2017
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Year of Publication 02.08.2017
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INHIBITORS OF HIF PROLYL HYDROXYLASE
WANG, Liping, CRESPO, Alejandro, CAI, Jiaqiang, KOTHANDARAMAN, Shankaran, DU, Xiaoxing, DUBOIS, Byron Gabriel, LIU, Rongqiang, QUAN, Weiguo, SINZ, Christopher, GUIADEEN, Deodialsingh, LIU, Ping
Year of Publication 02.08.2017
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Year of Publication 02.08.2017
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SUBSTITUTED CYCLOPROPYL COMPOUNDS
LIU, PING, EDMONDSON, SCOTT, D, WOOD, HAROLD, B, MILLER, MICHAEL, W, DUBOIS, BYRON, G, GEISS, WILLIAM, B, ACTON, JOHN, J
Year of Publication 29.06.2016
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Year of Publication 29.06.2016
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THIAZOLE-SUBSTITUTED AMINOPYRIMIDINES AS SPLEEN TYROSINE KINASE INHIBITORS
WANG LIPING, DUBOIS BYRON, LIU PING, ARRINGTON KENNETH L, DEBENHAM JOHN S, NORTHRUP ALAN B, SZEWCZYK JASON W, WANG MING
Year of Publication 03.03.2016
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Year of Publication 03.03.2016
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THIAZOLE-SUBSTITUTED AMINOPYRIMIDINES AS SPLEEN TYROSINE KINASE INHIBITORS
DEBENHAM, JOHN, S, LIU, PING, DUBOIS, BYRON, ARRINGTON, KENNETH, L, WANG, LIPING, SZEWCZYK, JASON, W, NORTHRUP, ALAN, B, WANG, MING
Year of Publication 02.03.2016
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Year of Publication 02.03.2016
Patent
SUBSTITUTED CYCLOPROPYL COMPOUNDS
LIU, PING, EDMONDSON, SCOTT, D, WOOD, HAROLD, B, MILLER, MICHAEL, W, DUBOIS, BYRON, G, GEISS, WILLIAM, B, ACTON, JOHN, J
Year of Publication 05.08.2015
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Year of Publication 05.08.2015
Patent
Isoquinoline derivatives as MGAT2 inhibitors
Blizzard, Timothy A, Liu, Ping, Zhang, Rui, Debenham, John S, Wang, Ming, Guo, Zack Zhiqiang, Xu, Jiayi, Campbell, Brian T, Dewnani, Sunita V, Dubois, Byron, Lin, Songnian, Xu, Libo, Hu, Zhiyong, Berger, Richard, Gude, Candido, Harper, Bart, Chen, Helen Y, Ujjainwalla, Feroze
Year of Publication 04.09.2018
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Year of Publication 04.09.2018
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