A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol
Chang, Chia-Jung, Chen, Chien-Hsiun, Chen, Bing-Mae, Su, Yu-Cheng, Chen, Ying-Ting, Hershfield, Michael S., Lee, Ming-Ta Michael, Cheng, Tian-Lu, Chen, Yuan-Tsong, Roffler, Steve R., Wu, Jer-Yuarn
Published in Nature communications (12.09.2017)
Published in Nature communications (12.09.2017)
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Journal Article
Ab locks for improving the selectivity and safety of antibody drugs
Lin, Wen-Wei, Lu, Yun-Chi, Chuang, Chih-Hung, Cheng, Tian-Lu
Published in Journal of biomedical science (25.06.2020)
Published in Journal of biomedical science (25.06.2020)
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Journal Article
Specific activation of pro-Infliximab enhances selectivity and safety of rheumatoid arthritis therapy
Lu, Yun-Chi, Chuang, Chih-Hung, Chuang, Kuo-Hsiang, Chen, I-Ju, Huang, Bo-Cheng, Lee, Wen-Han, Wang, Hsin-Ell, Li, Jia-Je, Cheng, Yi-An, Cheng, Kai-Wen, Wang, Jaw-Yuan, Hsieh, Yuan-Chin, Lin, Wen-Wei, Cheng, Tian-Lu
Published in PLoS biology (13.06.2019)
Published in PLoS biology (13.06.2019)
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Journal Article
Integrating molecular dynamics simulation with small‐ and wide‐angle X‐ray scattering to unravel the flexibility, antigen‐blocking, and protease‐restoring functions in a hindrance‐based pro‐antibody
Liao, Jun Min, Hong, Shih‐Ting, Wang, Yeng‐Tseng, Cheng, Yi‐An, Ho, Kai‐Wen, Toh, Shu‐Ing, Shih, Orion, Jeng, U‐Ser, Lyu, Ping‐Chiang, Hu, I‐Chen, Huang, Ming‐Yii, Chang, Chin‐Yuan, Cheng, Tian‐Lu
Published in Protein science (01.09.2024)
Published in Protein science (01.09.2024)
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Journal Article
Gut microbiota composition in chemotherapy and targeted therapy of patients with metastatic colorectal cancer
Chen, Yen-Cheng, Chuang, Chia-Hsien, Miao, Zhi-Feng, Yip, Kwan-Ling, Liu, Chung-Jung, Li, Ling-Hui, Wu, Deng-Chyang, Cheng, Tian−Lu, Lin, Chung-Yen, Wang, Jaw-Yuan
Published in Frontiers in oncology (23.09.2022)
Published in Frontiers in oncology (23.09.2022)
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Journal Article
Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes
Hsieh, Yuan-Chin, Wang, Hsin-Ell, Lin, Wen-Wei, Roffler, Steve R, Cheng, Ta-Chun, Su, Yu-Cheng, Li, Jia-Je, Chen, Chao-Cheng, Huang, Chun-Han, Chen, Bing-Mae, Wang, Jaw-Yuan, Cheng, Tian-Lu, Chen, Fang-Ming
Published in Theranostics (01.01.2018)
Published in Theranostics (01.01.2018)
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Journal Article
A non-genetic engineering platform for rapidly generating and expanding cancer-specific armed T cells
Chen, Yi-Jou, Chen, Michael, Cheng, Tian-Lu, Tsai, Yi-Shan, Wang, Chang-Hung, Chen, Che-Yi, Wu, Tung-Yun, Tzou, Shey-Cherng, Wang, Kai-Hung, Cheng, Jing-Jy, Kao, An-Pei, Lin, Shyr-Yi, Chuang, Kuo-Hsiang
Published in Journal of biomedical science (31.05.2023)
Published in Journal of biomedical science (31.05.2023)
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Journal Article
Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis
Cheng, Kai-Wen, Tseng, Chih-Hua, Chen, I.-Ju, Huang, Bo-Cheng, Liu, Hui-Ju, Ho, Kai-Wen, Lin, Wen-Wei, Chuang, Chih-Hung, Huang, Ming-Yii, Leu, Yu-Lin, Roffler, Steve R., Wang, Jaw-Yuan, Chen, Yeh-Long, Cheng, Tian-Lu
Published in Pharmacological research (01.03.2022)
Published in Pharmacological research (01.03.2022)
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Journal Article
Enhancement of tumor tropism of mPEGylated nanoparticles by anti-mPEG bispecific antibody for ovarian cancer therapy
Lin, Wen-Wei, Cheng, Yi-An, Li, Chia-Ching, Ho, Kai-Wen, Chen, Huei-Jen, Chen, I.-J.u, Huang, Bo-Cheng, Liu, Hui-Ju, Lu, Yun-Chi, Cheng, Chiu-Min, Huang, Ming-Yii, Lai, Hung-Wen, Cheng, Tian-Lu
Published in Scientific reports (07.04.2021)
Published in Scientific reports (07.04.2021)
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Journal Article
Chemical Constituent of β-Glucuronidase Inhibitors from the Root of Neolitsea acuminatissima
Lin, Chu-Hung, Chou, Hsiao-Jung, Chang, Chih-Chi, Chen, Ih-Sheng, Chang, Hsun-Shuo, Cheng, Tian-Lu, Kuo, Yueh-Hsiung, Ko, Horng-Huey
Published in Molecules (Basel, Switzerland) (06.11.2020)
Published in Molecules (Basel, Switzerland) (06.11.2020)
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Journal Article
Selective activation of pro-anti-IL-1β antibody enhances specificity for autoinflammatory disorder therapy
Lin, Wen-Wei, Lu, Yun-Chi, Huang, Bo-Cheng, Chuang, Chih-Hung, Cheng, Yi-An, Chen, I.-Ju, Liu, Hui-Ju, Ho, Kai-Wen, Liao, Tzu-Yi, Liu, En-Shuo, Wu, Ting-Yi, Chang, Long-Sen, Hong, Shih-Ting, Cheng, Tian-Lu
Published in Scientific reports (21.07.2021)
Published in Scientific reports (21.07.2021)
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Journal Article
ERCC1 Overexpression Increases Radioresistance in Colorectal Cancer Cells
Huang, Yi-Jung, Huang, Ming-Yii, Cheng, Tian-Lu, Kuo, Shih-Hsun, Ke, Chien-Chih, Chen, Yi-Ting, Hsieh, Yuan-Chin, Wang, Jaw-Yuan, Cheng, Chiu-Min, Chuang, Chih-Hung
Published in Cancers (30.09.2022)
Published in Cancers (30.09.2022)
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Journal Article
Development of a structure-based computational simulation to optimize the blocking efficacy of pro-antibodies
Huang, Bo-Cheng, Lu, Yun-Chi, Liao, Jun-Min, Liu, Hui-Ju, Hong, Shih-Ting, Hsieh, Yuan-Chin, Chuang, Chih-Hung, Chen, Huei-Jen, Liao, Tzu-Yi, Ho, Kai-Wen, Wang, Yeng-Tseng, Cheng, Tian-Lu
Published in Chemical science (Cambridge) (21.07.2021)
Published in Chemical science (Cambridge) (21.07.2021)
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Journal Article
Selective antibody activation through protease-activated pro-antibodies that mask binding sites with inhibitory domains
Chen, I-Ju, Chuang, Chih-Hung, Hsieh, Yuan-Chin, Lu, Yun-Chi, Lin, Wen-Wei, Huang, Chien-Chiao, Cheng, Ta-Chun, Cheng, Yi-An, Cheng, Kai-Wen, Wang, Yeng-Tseng, Chen, Fang-Ming, Cheng, Tian-Lu, Tzou, Shey-Cherng
Published in Scientific reports (14.09.2017)
Published in Scientific reports (14.09.2017)
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Journal Article
A Prospective Study of Comparing Multi-Gene Biomarker Chip and Serum Carcinoembryonic Antigen in the Postoperative Surveillance for Patients with Stage I-III Colorectal Cancer
Chang, Yu-Tang, Huang, Ming-Yii, Yeh, Yung-Sung, Huang, Ching-Wen, Tsai, Hsiang-Lin, Cheng, Tian-Lu, Wang, Jaw-Yuan
Published in PloS one (04.10.2016)
Published in PloS one (04.10.2016)
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Journal Article