Detecting HLA loss of heterozygosity within a standard diagnostic sequencing workflow for prognostic and therapeutic opportunities
Lozac’hmeur, Ariane, Danek, Tyler, Yang, Qidi, Rosasco, Mario G., Welch, John S., Go, William Y., Ng, Eric W., Mardiros, Armen, Maloney, David G., Garon, Edward B., Kirtane, Kedar, Simeone, Diane M., Molina, Julian R., Salahudeen, Ameen A., Stein, Michelle M., Hecht, J. Randolph
Published in NPJ precision oncology (05.08.2024)
Published in NPJ precision oncology (05.08.2024)
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Genomic Immune Evasion: Diagnostic and Therapeutic Opportunities in Head and Neck Squamous Cell Carcinomas
Kirtane, Kedar, St John, Maie, Fuentes-Bayne, Harry, Patel, Sandip P, Mardiros, Armen, Xu, Han, Ng, Eric W, Go, William Y, Wong, Deborah J, Sunwoo, John B, Welch, John S
Published in Journal of clinical medicine (07.12.2022)
Published in Journal of clinical medicine (07.12.2022)
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634 EVEREST-1: A seamless phase 1/2 study of CEA logic-gated Tmod CAR T-cell therapy (A2B530) in patients with solid tumors associated with CEA expression also exhibiting HLA loss of heterozygosity (LOH)
Punekar, Salman R, Welling, Theodore, Randolph Hecht, J, Molina, Julian, Smith, Caleb, Garon, Edward, Pia Morelli, M, Fakih, Marwan, Kirtane, Kedar, Grierson, Patrick M, Patel, Sandip P, Lin, Yi, Kopetz, Scott, Locke, Frederick L, Ward, Jeffrey, Lozac’hmeur, Ariane, Frigault, Matthew, Nikiforow, Sarah, Weng, Wen-Kai, Specht, Jennifer, Dragovich, Tomislav, Vong, Judy, Mardiros, Armen, Liechty, Kirstin, Go, William Y, Welch, John, Ng, Eric W, Maus, Marcela, Maloney, David, Simeone, Diane M
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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491 BASECAMP-1: an observational study to identify relapsed solid tumor patients with human leukocyte antigen (HLA) loss of heterozygosity (LOH) and leukapheresis for future CAR T-cell therapy
Molina, Julian, Go, William, Kopetz, Scott, Simeone, Diane, Patel, Sandip, Lin, Yi, Liechty, Kirstin, Fan-Port, Michelle, Perera, Jason, Mardiros, Armen, Beutner, Karl, Lozac’hmeur, Ariane, Ng, Eric, Maloney, David, Randolph Hecht, J
Published in Journal for immunotherapy of cancer (01.11.2021)
Published in Journal for immunotherapy of cancer (01.11.2021)
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T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia
Mardiros, Armen, Dos Santos, Cedric, McDonald, Tinisha, Brown, Christine E., Wang, Xiuli, Budde, L. Elizabeth, Hoffman, Lauren, Aguilar, Brenda, Chang, Wen-Chung, Bretzlaff, William, Chang, Brenda, Jonnalagadda, Mahesh, Starr, Renate, Ostberg, Julie R., Jensen, Michael C., Bhatia, Ravi, Forman, Stephen J.
Published in Blood (31.10.2013)
Published in Blood (31.10.2013)
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TGF-β Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy
Kato, Mitsuo, Dang, Varun, Wang, Mei, Park, Jung Tak, Deshpande, Supriya, Kadam, Swati, Mardiros, Armen, Zhan, Yumei, Oettgen, Peter, Putta, Sumanth, Yuan, Hang, Lanting, Linda, Natarajan, Rama
Published in Science signaling (04.06.2013)
Published in Science signaling (04.06.2013)
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Chimeric Antigen Receptors With Mutated IgG4 Fc Spacer Avoid Fc Receptor Binding and Improve T Cell Persistence and Antitumor Efficacy
Jonnalagadda, Mahesh, Mardiros, Armen, Urak, Ryan, Wang, Xiuli, Hoffman, Lauren J, Bernanke, Alyssa, Chang, Wen-Chung, Bretzlaff, William, Starr, Renate, Priceman, Saul, Ostberg, Julie R, Forman, Stephen J, Brown, Christine E
Published in Molecular therapy (01.04.2015)
Published in Molecular therapy (01.04.2015)
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T cells expressing CD123 chimeric antigen receptors for treatment of acute myeloid leukemia
Mardiros, Armen, Forman, Stephen J, Budde, Lihua E
Published in Current opinion in hematology (01.11.2015)
Published in Current opinion in hematology (01.11.2015)
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Glioma immunotherapy enhancement and CD8-specific sialic acid cleavage by isocitrate dehydrogenase (IDH)-1
Cordner, Ryan, Jhun, Michelle, Panwar, Akanksha, Wang, HongQiang, Gull, Nicole, Murali, Ramachandran, McAbee, Joseph H., Mardiros, Armen, Sanchez-Takei, Akane, Mazer, Mia W., Fan, Xuemo, Jouanneau, Emmanuel, Yu, John S., Black, Keith L., Wheeler, Christopher J.
Published in Oncogene (16.06.2023)
Published in Oncogene (16.06.2023)
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First-in-human data of ALLO-501 and ALLO-647 in relapsed/refractory large B-cell or follicular lymphoma (R/R LBCL/FL): ALPHA study
Neelapu, Sattva Swarup, Munoz, Javier, Locke, Frederick Lundry, Miklos, David Bernard, Brown, Robert, McDevitt, Jennifer T., Mardiros, Armen, Demirhan, Eren, Konto, Cyril, Tees, Michael Timothy
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Antigen-specific age-related memory CD8 T cells induce and track Alzheimer's-like neurodegeneration
Panwar, Akanksha, Rentsendorj, Altan, Jhun, Michelle, Cohen, Robert M, Cordner, Ryan, Gull, Nicole, Pechnick, Robert N, Duvall, Gretchen, Mardiros, Armen, Golchian, David, Schubloom, Hannah, Jin, Lee-Way, Van Dam, Debby, Vermeiren, Yannick, De Reu, Hans, De Deyn, Peter Paul, Raskatov, Jevgenij A, Black, Keith L, Irvin, Dwain K, Williams, Brian A, Wheeler, Christopher J
Published in Proceedings of the National Academy of Sciences - PNAS (16.07.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (16.07.2024)
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Prospective BASECAMP-1 experience in patients with gastrointestinal (GI) cancer: Identifying patients with human leukocyte antigen (HLA) loss of heterozygosity (LOH) for a future therapeutic trial exploiting LOH as a tumor vulnerability
Hecht, J. Randolph, Kopetz, Scott, Welling, Theodore, Morelli, Maria Pia, Molina, Julian R., Kirtane, Kedar, Oberstein, Paul Eliezer, Greenwald, Daniel R., Lin, Yi, Mardiros, Armen, Beutner, Karl, Lozac'hmeur, Ariane, Salahudeen, Ameen, Liechty, Kirstin B., Vong, Judy, Ng, Eric Wai-Choi, Maloney, David G., Go, William Y., Welch, John Sutton, Simeone, Diane M.
Published in Journal of clinical oncology (01.02.2023)
Published in Journal of clinical oncology (01.02.2023)
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Next generation sequencing (NGS) to identify relapsed gastrointestinal (GI) solid tumor patients with human leukocyte antigen (HLA) loss of heterozygosity (LOH) for future logic-gated CAR T therapy to reduce on target off tumor toxicity
Hecht, J. Randolph Randolph, Kopetz, Scott, Patel, Sandip Pravin, Welling, Theodore, Morelli, Maria Pia, Borad, Mitesh J., Molina, Julian R., Kirtane, Kedar, Lin, Yi, Fan-Port, Michelle, Mardiros, Armen, Beutner, Karl, Lozac'hmeur, Ariane, Lau, Denise, Liechty, Kirstin B., Vong, Judy, Ng, Eric, Maloney, David G., Go, William Y., Simeone, Diane M.
Published in Journal of clinical oncology (01.02.2022)
Published in Journal of clinical oncology (01.02.2022)
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Functional recreation of age-related CD8 T cells in young mice identifies drivers of aging- and human-specific tissue pathology
Panwar, Akanksha, Jhun, Michelle, Rentsendorj, Altan, Mardiros, Armen, Cordner, Ryan, Birch, Kurtis, Yeager, Nicole, Duvall, Gretchen, Golchian, David, Koronyo-Hamaoui, Maya, Cohen, Robert M., Ley, Eric, Black, Keith L., Wheeler, Christopher J.
Published in Mechanisms of ageing and development (01.10.2020)
Published in Mechanisms of ageing and development (01.10.2020)
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Abstract 2135: Selectivity and specificity of engineered T cells expressing KITE-585, a chimeric antigen receptor targeting B-cell maturation antigen (BCMA)
Adams, Gregor B., Feng, Jun, Ghogha, Atefeh, Mardiros, Armen, Rodriguez, Ruben, Spindler, Tassja J., Wiltzius, Jed, Polverino, Tony
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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CMVpp65 Vaccine Enhances the Antitumor Efficacy of Adoptively Transferred CD19-Redirected CMV-Specific T Cells
Wang, Xiuli, Wong, ChingLam W, Urak, Ryan, Mardiros, Armen, Budde, Lihua E, Chang, Wen-Chung, Thomas, Sandra H, Brown, Christine E, La Rosa, Corinna, Diamond, Don J, Jensen, Michael C, Nakamura, Ryotaro, Zaia, John A, Forman, Stephen J
Published in Clinical cancer research (01.07.2015)
Published in Clinical cancer research (01.07.2015)
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