Implications of the 375W mutation for HIV-1 tropism and vaccine development
Verdejo-Torres, Odette, Vargas-Pavia, Tania, Fatima, Syeda, Clapham, Paul R, Duenas-Decamp, Maria J
Published in Journal of virology (23.01.2024)
Published in Journal of virology (23.01.2024)
Get full text
Journal Article
Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality
Beauparlant, David, Rusert, Peter, Magnus, Carsten, Kadelka, Claus, Weber, Jacqueline, Uhr, Therese, Zagordi, Osvaldo, Oberle, Corinna, Duenas-Decamp, Maria J, Clapham, Paul R, Metzner, Karin J, Günthard, Huldrych F, Trkola, Alexandra
Published in PLOS Pathogens (06.03.2017)
Published in PLOS Pathogens (06.03.2017)
Get full text
Journal Article
Macrophages in Vaginal but Not Intestinal Mucosa Are Monocyte-Like and Permissive to Human Immunodeficiency Virus Type 1 Infection
RUIZHONG SHEN, RICHTER, Holly E, SMITH, Phillip D, CLEMENTS, Ronald H, NOVAK, Lea, HUFF, Kayci, BIMCZOK, Diane, SANKARAN-WALTERS, Sumathi, DANDEKAR, Satya, CLAPHAM, Paul R, SMYTHIES, Lesley E
Published in Journal of Virology (01.04.2009)
Published in Journal of Virology (01.04.2009)
Get full text
Journal Article
Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications
Gonzalez-Perez, Maria Paz, Peters, Paul J, O'Connell, Olivia, Silva, Nilsa, Harbison, Carole, Cummings Macri, Sheila, Kaliyaperumal, Saravanan, Luzuriaga, Katherine, Clapham, Paul R
Published in Journal of virology (15.10.2017)
Published in Journal of virology (15.10.2017)
Get full text
Journal Article
Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue
Gonzalez-Perez, Maria Paz, O'Connell, Olivia, Lin, Rongheng, Sullivan, W Matthew, Bell, Jeanne, Simmonds, Peter, Clapham, Paul R
Published in Retrovirology (15.03.2012)
Published in Retrovirology (15.03.2012)
Get full text
Journal Article
Genotypic and functional properties of early infant HIV-1 envelopes
Kishko, Michael, Somasundaran, Mohan, Brewster, Frank, Sullivan, John L, Clapham, Paul R, Luzuriaga, Katherine
Published in Retrovirology (15.08.2011)
Published in Retrovirology (15.08.2011)
Get full text
Journal Article
HIV-1 R5 Macrophage-Tropic Envelope Glycoprotein Trimers Bind CD4 with High Affinity, while the CD4 Binding Site on Non-macrophage-tropic, T-Tropic R5 Envelopes Is Occluded
Quitadamo, Briana, Peters, Paul J, Repik, Alexander, O'Connell, Olivia, Mou, Zhongming, Koch, Matthew, Somasundaran, Mohan, Brody, Robin, Luzuriaga, Katherine, Wallace, Aaron, Wang, Shixia, Lu, Shan, McCauley, Sean, Luban, Jeremy, Duenas-Decamp, Maria, Gonzalez-Perez, Maria Paz, Clapham, Paul R
Published in Journal of virology (15.01.2018)
Published in Journal of virology (15.01.2018)
Get full text
Journal Article
Gag Regulates Association of Human Immunodeficiency Virus Type 1 Envelope with Detergent-Resistant Membranes
BHATTACHARYA, Jayanta, REPIK, Alexander, CLAPHAM, Paul R
Published in Journal of Virology (01.06.2006)
Published in Journal of Virology (01.06.2006)
Get full text
Journal Article
Ultradeep single-molecule real-time sequencing of HIV envelope reveals complete compartmentalization of highly macrophage-tropic R5 proviral variants in brain and CXCR4-using variants in immune and peripheral tissues
Brese, Robin L., Gonzalez-Perez, Maria Paz, Koch, Matthew, O’Connell, Olivia, Luzuriaga, Katherine, Somasundaran, Mohan, Clapham, Paul R., Dollar, James Jarad, Nolan, David J, Rose, Rebecca, Lamers, Susanna L.
Published in Journal of neurovirology (01.08.2018)
Published in Journal of neurovirology (01.08.2018)
Get full text
Journal Article
No detection of CD4-independent human immunodeficiency virus 1 envelope glycoproteins in brain tissue of patients with or without neurological complications
Quitadamo, Briana, Peters, Paul J., Koch, Matthew, Luzuriaga, Katherine, Cheng-Mayer, Cecilia, Clapham, Paul R., Gonzalez-Perez, Maria Paz
Published in Archives of virology (01.02.2019)
Published in Archives of virology (01.02.2019)
Get full text
Journal Article
A Conserved Determinant in the V1 Loop of HIV-1 Modulates the V3 Loop To Prime Low CD4 Use and Macrophage Infection
Musich, Thomas, Peters, Paul J, Duenas-Decamp, Maria José, Gonzalez-Perez, Maria Paz, Robinson, James, Zolla-Pazner, Susan, Ball, Jonathan K, Luzuriaga, Katherine, Clapham, Paul R
Published in Journal of Virology (01.03.2011)
Published in Journal of Virology (01.03.2011)
Get full text
Journal Article
Natural Resistance of Human Immunodeficiency Virus Type 1 to the CD4bs Antibody b12 Conferred by a Glycan and an Arginine Residue Close to the CD4 Binding Loop
DUENAS-DECAMP, Maria José, PETERS, Paul, BURTON, Dennis, CLAPHAM, Paul R
Published in Journal of Virology (01.06.2008)
Published in Journal of Virology (01.06.2008)
Get full text
Journal Article
Biological Analysis of Human Immunodeficiency Virus Type 1 R5 Envelopes Amplified from Brain and Lymph Node Tissues of AIDS Patients with Neuropathology Reveals Two Distinct Tropism Phenotypes and Identifies Envelopes in the Brain That Confer an Enhanced Tropism and Fusigenicity for Macrophages
PETERS, Paul J, BHATTACHARYA, Jayanta, HIBBITTS, Samantha, DITTMAR, Matthias T, SIMMONS, Graham, BELL, Jeanne, SIMMONDS, Peter, CLAPHAM, Paul R
Published in Journal of Virology (01.07.2004)
Published in Journal of Virology (01.07.2004)
Get full text
Journal Article
Intercompartmental Recombination of HIV-1 Contributes to env Intrahost Diversity and Modulates Viral Tropism and Sensitivity to Entry Inhibitors
BROWN, Richard J. P, PETERS, Paul J, SHARP, Paul M, CLAPHAM, Paul R, BALL, Jonathan K, CARON, Catherine, PAZ GONZALEZ-PEREZ, Maria, STONES, Leanne, ANKGHUAMBOM, Chiambah, PONDEI, Kemebradikumo, PATRICK MCCLURE, C, ALEMNJI, George, TAYLOR, Stephen
Published in Journal of Virology (01.06.2011)
Published in Journal of Virology (01.06.2011)
Get full text
Journal Article