Effect of alcohol coadministration on the pharmacodynamics, pharmacokinetics, and safety of lemborexant: A randomized, placebo-controlled crossover study
Landry, Ishani, Hall, Nancy, Aluri, Jagadeesh, Filippov, Gleb, Setnik, Beatrice, Dayal, Satish, Reyderman, Larisa, Moline, Margaret
Published in Journal of psychopharmacology (01.06.2022)
Published in Journal of psychopharmacology (01.06.2022)
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Journal Article
Pharmacokinetics, Pharmacodynamics, and Safety of the Dual Orexin Receptor Antagonist Lemborexant: Findings From Single‐Dose and Multiple‐Ascending‐Dose Phase 1 Studies in Healthy Adults
Landry, Ishani, Nakai, Kenya, Ferry, Jim, Aluri, Jagadeesh, Hall, Nancy, Lalovic, Bojan, Moline, Margaret L.
Published in Clinical Pharmacology in Drug Development (01.02.2021)
Published in Clinical Pharmacology in Drug Development (01.02.2021)
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Journal Article
Effect of Rifampicin on the Pharmacokinetics of Lenvatinib in Healthy Adults
Shumaker, Robert C., Aluri, Jagadeesh, Fan, Jean, Martinez, Gresel, Thompson, Gary A., Ren, Min
Published in Clinical Drug Investigation (01.09.2014)
Published in Clinical Drug Investigation (01.09.2014)
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Journal Article
Concentration–Response Modeling of ECG Data From Early‐Phase Clinical Studies as an Alternative Clinical and Regulatory Approach to Assessing QT Risk — Experience From the Development Program of Lemborexant
Murphy, Patricia J., Yasuda, Sanae, Nakai, Kenya, Yoshinaga, Takashi, Hall, Nancy, Zhou, Meijian, Aluri, Jagadeesh, Rege, Bhaskar, Moline, Margaret, Ferry, Jim, Darpo, Borje
Published in Journal of clinical pharmacology (01.01.2017)
Published in Journal of clinical pharmacology (01.01.2017)
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Journal Article
Population pharmacokinetic‐pharmacodynamic modeling of serum biomarkers as predictors of tumor dynamics following lenvatinib treatment in patients with radioiodine‐refractory differentiated thyroid cancer (RR‐DTC)
Majid, Oneeb, Hayato, Seiichi, Sreerama Reddy, Sree Harsha, Lalovic, Bojan, Hihara, Taro, Hoshi, Taisuke, Funahashi, Yasuhiro, Aluri, Jagadeesh, Takenaka, Osamu, Yasuda, Sanae, Hussein, Ziad
Published in CPT: Pharmacometrics & Systems Pharmacology (01.06.2024)
Published in CPT: Pharmacometrics & Systems Pharmacology (01.06.2024)
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Journal Article
Evaluation of the effects of formulation and food on the pharmacokinetics of lenvatinib (E7080) in healthy volunteers
Shumaker, Robert, Aluri, Jagadeesh, Fan, Jean, Martinez, Gresel, Ren, Min, Chen, Kun
Published in Int. Journal of Clinical Pharmacology and Therapeutics (01.04.2014)
Published in Int. Journal of Clinical Pharmacology and Therapeutics (01.04.2014)
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Journal Article
Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant
Landry, Ishani, Aluri, Jagadeesh, Hall, Nancy, Filippov, Gleb, Dayal, Satish, Moline, Margaret, Reyderman, Larisa
Published in Pharmacology Research & Perspectives (01.04.2021)
Published in Pharmacology Research & Perspectives (01.04.2021)
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Journal Article
Bioavailability of Three Rufinamide Oral Suspensions Compared With the Marketed 400-mg Tablet Formulation: Results From a Randomized-Sequence, Open-Label, Four-Period, Four-Sequence Crossover Study in Healthy Subjects
Critchley, David John, PhD, Aluri, Jagadeesh, MS, Boyd, Peter, MSc, Whayman, Matthew, MSc, Narurkar, Milind, PhD, Delargy, Hugh, PhD, Bibbiani, Francesco, MD
Published in Clinical therapeutics (2011)
Published in Clinical therapeutics (2011)
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Journal Article
Abuse Potential of Lemborexant, a Dual Orexin Receptor Antagonist, Compared With Zolpidem and Suvorexant in Recreational Sedative Users
Landry, Ishani, Hall, Nancy, Aluri, Jagadeesh, Filippov, Gleb, Reyderman, Larisa, Setnik, Beatrice, Henningfield, Jack, Moline, Margaret
Published in Journal of clinical psychopharmacology (01.07.2022)
Published in Journal of clinical psychopharmacology (01.07.2022)
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Journal Article
Lemborexant levels in breast milk after single doses in healthy, lactating women
Rawal, Sumit, Brimhall, Darin, Aluri, Jagadeesh, Cheng, Jocelyn Y., Hall, Nancy, Moline, Margaret
Published in BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology (01.01.2024)
Published in BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology (01.01.2024)
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Journal Article
Subcutaneous (SC) lecanemab is predicted to achieve comparable efficacy and improved safety compared to lecanemab IV in early Alzheimer’s disease (AD)
Willis, Brian A., Penner, Natasha, Rawal, Sumit, Aluri, Jagadeesh, Reyderman, Larisa
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Safety, Pharmacokinetics and Immunogenicity of Single and Multiple Ascending Doses of the Anti‐Tau Therapeutic Antibody E2814: A Phase 1, First‐In‐Human (FIH) Study in Healthy Subjects
Rawal, Sumit, Yagi, Takuya, Boyd, Peter, Aluri, Jagadeesh, Wildsmith, Kristin R, Reyderman, Larisa
Published in Alzheimer's & dementia (01.12.2023)
Published in Alzheimer's & dementia (01.12.2023)
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Journal Article
Population Pharmacokinetics and Exposure‐Response Analyses for the Most Frequent Adverse Events Following Treatment With Lemborexant, an Orexin Receptor Antagonist, in Subjects With Insomnia Disorder
Lalovic, Bojan, Majid, Oneeb, Aluri, Jagadeesh, Landry, Ishani, Moline, Margaret, Hussein, Ziad
Published in Journal of clinical pharmacology (01.12.2020)
Published in Journal of clinical pharmacology (01.12.2020)
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Journal Article
Disposition and Metabolism of [ 14 C]Lemborexant in Healthy Human Subjects and Characterization of Its Circulating Metabolites
Ueno, Takashi, Ishida, Tomomi, Aluri, Jagadeesh, Suzuki, Michiyuki, Beuckmann, Carsten T, Kameyama, Takaaki, Asakura, Shoji, Kusano, Kazutomi
Published in Drug metabolism and disposition (01.01.2021)
Published in Drug metabolism and disposition (01.01.2021)
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Journal Article
Phase 1 Single Ascending and Multiple Ascending Dose Studies of Phosphodiesterase-9 Inhibitor E2027: Confirmation of Target Engagement and Selection of Phase 2 Dose in Dementia With Lewy Bodies Trial
Landry, Ishani S, Aluri, Jagadeesh, Schuck, Edgar, Ino, Mitsuhiro, Horie, Kanta, Boyd, Peter, Reyderman, Larisa, Lai, Robert
Published in Alzheimer disease and associated disorders (01.07.2022)
Published in Alzheimer disease and associated disorders (01.07.2022)
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Journal Article
Abstract 5050: Pharmacodynamic and pharmacokinetic relationship of single agent E7449 in patients with advanced solid tumors or B-cell malignancies
Sachdev, Pallavi, McGrath, Shannon, Shumaker, Robert, Aluri, Jagadeesh, Savulsky, Claudio
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article