The Trypanosoma cruzi TcTASV-C protein subfamily administrated with U-Omp19 promotes a protective response against a lethal challenge in mice
Caeiro, Lucas D., Masip, Yamil E., Rizzi, Mariana, Rodríguez, Matías E., Pueblas Castro, Celeste, Sánchez, Daniel O., Coria, M. Lorena, Cassataro, Juliana, Tekiel, Valeria
Published in Vaccine (10.11.2020)
Published in Vaccine (10.11.2020)
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A Novel Bacterial Protease Inhibitor Adjuvant in RBD-Based COVID-19 Vaccine Formulations Containing Alum Increases Neutralizing Antibodies, Specific Germinal Center B Cells and Confers Protection Against SARS-CoV-2 Infection in Mice
Coria, Lorena M, Saposnik, Lucas M, Pueblas Castro, Celeste, Castro, Eliana F, Bruno, Laura A, Stone, William B, Pérez, Paula S, Darriba, Maria Laura, Chemes, Lucia B, Alcain, Julieta, Mazzitelli, Ignacio, Varese, Augusto, Salvatori, Melina, Auguste, Albert J, Álvarez, Diego E, Pasquevich, Karina A, Cassataro, Juliana
Published in Frontiers in immunology (28.02.2022)
Published in Frontiers in immunology (28.02.2022)
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Immunization with Recombinant Brucella Species Outer Membrane Protein Omp16 or Omp19 in Adjuvant Induces Specific CD4⁺ and CD8⁺ T Cells as Well as Systemic and Oral Protection against Brucella abortus Infection
Pasquevich, Karina A, Estein, Silvia M, Samartino, Clara García, Zwerdling, Astrid, Coria, Lorena M, Barrionuevo, Paula, Fossati, Carlos A, Giambartolomei, Guillermo H, Cassataro, Juliana
Published in Infection and Immunity (01.01.2009)
Published in Infection and Immunity (01.01.2009)
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An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice
Pasquevich, Karina A, Ibañez, Andrés E, Coria, Lorena M, García Samartino, Clara, Estein, Silvia M, Zwerdling, Astrid, Barrionuevo, Paula, Oliveira, Fernanda S, Seither, Christine, Warzecha, Heribert, Oliveira, Sergio C, Giambartolomei, Guillermo H, Cassataro, Juliana
Published in PloS one (14.01.2011)
Published in PloS one (14.01.2011)
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Omp19 Enables Brucella abortus to Evade the Antimicrobial Activity From Host's Proteolytic Defense System
Pasquevich, Karina A, Carabajal, Marianela V, Guaimas, Francisco F, Bruno, Laura, Roset, Mara S, Coria, Lorena M, Rey Serrantes, Diego A, Comerci, Diego J, Cassataro, Juliana
Published in Frontiers in immunology (26.06.2019)
Published in Frontiers in immunology (26.06.2019)
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A disordered region retains the full protease inhibitor activity and the capacity to induce CD8+ T cells in vivo of the oral vaccine adjuvant U-Omp19
Laura Darriba, M., Castro, Celeste Pueblas, Coria, Lorena M., Bruno, Laura, Laura Cerutti, M., Otero, Lisandro H., Chemes, Lucía B., Rasia, Rodolfo M., Klinke, Sebastián, Cassataro, Juliana, Pasquevich, Karina A.
Published in Computational and structural biotechnology journal (2022)
Published in Computational and structural biotechnology journal (2022)
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Journal Article
Unlipidated outer membrane protein Omp16 (U-Omp16) from Brucella spp. as nasal adjuvant induces a Th1 immune response and modulates the Th2 allergic response to cow's milk proteins
Ibañez, Andrés E, Smaldini, Paola, Coria, Lorena M, Delpino, María V, Pacífico, Lucila G G, Oliveira, Sergio C, Risso, Gabriela S, Pasquevich, Karina A, Fossati, Carlos Alberto, Giambartolomei, Guillermo H, Docena, Guillermo H, Cassataro, Juliana
Published in PloS one (05.07.2013)
Published in PloS one (05.07.2013)
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U-Omp19 from Brucella abortus increases dmLT immunogenicity and improves protection against Escherichia coli heat-labile toxin (LT) oral challenge
Coria, Lorena M., Martinez, Franco L., Bruno, Laura A., Pasquevich, Karina A., Cassataro, Juliana
Published in Vaccine (06.07.2020)
Published in Vaccine (06.07.2020)
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Oral co-administration of a bacterial protease inhibitor in the vaccine formulation increases antigen delivery at the intestinal epithelial barrier
Coria, Lorena M., Risso, Gabriela S., Guaimas, Francisco F., Ferrero, Mariana C., Bruno, Laura, Pasquevich, Karina A., Cassataro, Juliana
Published in Journal of controlled release (10.01.2019)
Published in Journal of controlled release (10.01.2019)
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Safety and immunogenicity of a SARS-CoV-2 Gamma variant RBD-based protein adjuvanted vaccine used as booster in healthy adults
Pasquevich, Karina A., Coria, Lorena M., Ceballos, Ana, Mazzitelli, Bianca, Rodriguez, Juan Manuel, Demaría, Agostina, Pueblas Castro, Celeste, Bruno, Laura, Saposnik, Lucas, Salvatori, Melina, Varese, Augusto, González, Soledad, González Martínez, Veronica V., Geffner, Jorge, Álvarez, Diego, Feleder, Ethel, Halabe, Karina, Perez Lera, Pablo E., de Oca, Federico Montes, Vega, Julio C., Lombardo, Mónica, Yerino, Gustavo A., Fló, Juan, Cassataro, Juliana
Published in Nature communications (28.07.2023)
Published in Nature communications (28.07.2023)
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A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection
Coria, Lorena M., Rodriguez, Juan Manuel, Demaria, Agostina, Bruno, Laura A., Medrano, Mayra Rios, Castro, Celeste Pueblas, Castro, Eliana F., Del Priore, Sabrina A., Hernando Insua, Andres C., Kaufmann, Ingrid G., Saposnik, Lucas M., Stone, William B., Prado, Lineia, Notaro, Ulises S., Amweg, Ayelen N., Diaz, Pablo U., Avaro, Martin, Ortega, Hugo, Ceballos, Ana, Krum, Valeria, Zurvarra, Francisco M., Sidabra, Johanna E., Drehe, Ignacio, Baqué, Jonathan A., Li Causi, Mariana, De Nichilo, Analia V., Payes, Cristian J., Southard, Teresa, Vega, Julio C., Auguste, Albert J., Álvarez, Diego E., Flo, Juan M., Pasquevich, Karina A., Cassataro, Juliana
Published in Nature communications (02.02.2024)
Published in Nature communications (02.02.2024)
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A Brucella spp. Protease Inhibitor Limits Antigen Lysosomal Proteolysis, Increases Cross-Presentation, and Enhances CD8+ T Cell Responses
Coria, Lorena M, Ibañez, Andrés E, Tkach, Mercedes, Sabbione, Florencia, Bruno, Laura, Carabajal, Marianela V, Berguer, Paula M, Barrionuevo, Paula, Schillaci, Roxana, Trevani, Analía S, Giambartolomei, Guillermo H, Pasquevich, Karina A, Cassataro, Juliana
Published in The Journal of immunology (1950) (15.05.2016)
Published in The Journal of immunology (1950) (15.05.2016)
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Journal Article
The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis
Pasquevich, Karina A, García Samartino, Clara, Coria, Lorena M, Estein, Silvia M, Zwerdling, Astrid, Ibañez, Andrés E, Barrionuevo, Paula, Oliveira, Fernanda Souza de, Carvalho, Natalia Barbosa, Borkowski, Julia, Oliveira, Sergio Costa, Warzecha, Heribert, Giambartolomei, Guillermo H, Cassataro, Juliana
Published in The Journal of immunology (1950) (01.05.2010)
Published in The Journal of immunology (1950) (01.05.2010)
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Journal Article
U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice
Risso, Gabriela S, Carabajal, Marianela V, Bruno, Laura A, Ibañez, Andrés E, Coria, Lorena M, Pasquevich, Karina A, Lee, Seung-Joo, McSorley, Stephen J, Briones, Gabriel, Cassataro, Juliana
Published in Frontiers in immunology (17.02.2017)
Published in Frontiers in immunology (17.02.2017)
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Journal Article
Brucella abortus Omp19 recombinant protein subcutaneously co-delivered with an antigen enhances antigen-specific T helper 1 memory responses and induces protection against parasite challenge
Coria, Lorena M, Ibañez, Andrés E, Pasquevich, Karina A, Cobiello, Paula L. González, Frank, Fernanda M, Giambartolomei, Guillermo H, Cassataro, Juliana
Published in Vaccine (20.01.2016)
Published in Vaccine (20.01.2016)
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Journal Article
Brucella abortus induces apoptosis of human T lymphocytes
Velásquez, Lis N., Delpino, M. Victoria, Ibañez, Andrés E., Coria, Lorena M., Miraglia, M. Cruz, Scian, Romina, Cassataro, Juliana, Giambartolomei, Guillermo H., Barrionuevo, Paula
Published in Microbes and infection (01.07.2012)
Published in Microbes and infection (01.07.2012)
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Journal Article
The polymeric antigen BLSOmp31 confers protection against Brucella ovis infection in rams
Estein, Silvia M, Fiorentino, María A, Paolicchi, Fernando A, Clausse, María, Manazza, Jorge, Cassataro, Juliana, Giambartolomei, Guillermo H, Coria, Lorena M, Zylberman, Vanesa, Fossati, Carlos A, Kjeken, Rune, Goldbaum, Fernando A
Published in Vaccine (12.11.2009)
Published in Vaccine (12.11.2009)
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Journal Article
Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases
Miraglia, M Cruz, Scian, Romina, Samartino, Clara García, Barrionuevo, Paula, Rodriguez, Ana M, Ibañez, Andrés E, Coria, Lorena M, Velásquez, Lis N, Baldi, Pablo C, Cassataro, Juliana, Delpino, M Victoria, Giambartolomei, Guillermo H
Published in Journal of neuroinflammation (12.04.2013)
Published in Journal of neuroinflammation (12.04.2013)
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Journal Article
Brucella abortus inhibits IFN-γ-induced FcγRI expression and FcγRI-restricted phagocytosis via toll-like receptor 2 on human monocytes/macrophages
Barrionuevo, Paula, Delpino, M. Victoria, Velásquez, Lis N., García Samartino, Clara, Coria, Lorena M., Ibañez, Andrés E., Rodríguez, María Eugenia, Cassataro, Juliana, Giambartolomei, Guillermo H.
Published in Microbes and infection (01.03.2011)
Published in Microbes and infection (01.03.2011)
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Journal Article
Brucella abortusinduces TNF-[alpha]-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases
Miraglia, M Cruz, Scian, Romina, Sama, Barrionuevo, Paula, Rodriguez, Ana M, Ibaéez, Andrñs E, Coria, Lorena M, Velásquez, Lis N, Baldi, Pablo C, Cassataro, Juliana, Delpino, M Victoria, Giambartolomei, Guillermo H
Published in Journal of neuroinflammation (12.04.2013)
Published in Journal of neuroinflammation (12.04.2013)
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