Antibacterial Spirotetronate Polyketides from an Actinomadura sp. Strain A30804
Ching, Kuan-Chieh, Chin, Elaine J, Wibowo, Mario, Tan, Zann Y, Yang, Lay-Kien, Seow, Deborah C, Leong, Chung-Yan, Ng, Veronica W, Ng, Siew-Bee, Kanagasundaram, Yoganathan
Published in Molecules (Basel, Switzerland) (24.11.2022)
Published in Molecules (Basel, Switzerland) (24.11.2022)
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Natural Products from Singapore Soil-Derived Streptomycetaceae Family and Evaluation of Their Biological Activities
Chin, Elaine-Jinfeng, Ching, Kuan-Chieh, Tan, Zann Y, Wibowo, Mario, Leong, Chung-Yan, Yang, Lay-Kien, Ng, Veronica W P, Seow, Deborah C S, Kanagasundaram, Yoganathan, Ng, Siew-Bee
Published in Molecules (Basel, Switzerland) (02.08.2023)
Published in Molecules (Basel, Switzerland) (02.08.2023)
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Hypoculoside, a sphingoid base-like compound from Acremonium disrupts the membrane integrity of yeast cells
Alfatah, Mohammad, Wong, Jin Huei, Nge, Choy Eng, Kong, Kiat Whye, Low, Kia Ngee, Leong, Chung Yan, Crasta, Sharon, Munusamy, Madhaiyan, Chang, Amanda Mun Leng, Hoon, Shawn, Ng, Siew Bee, Kanagasundaram, Yoganathan, Arumugam, Prakash
Published in Scientific reports (24.01.2019)
Published in Scientific reports (24.01.2019)
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Antibacterial Thiopeptide GE2270-Congeners from Nonomuraea jiangxiensis
Ching, Kuan-Chieh, Chin, Elaine J, Wibowo, Mario, Tan, Zann Y, Yang, Lay-Kien, Seow, Deborah C, Leong, Chung-Yan, Ng, Veronica W, Ng, Siew-Bee, Kanagasundaram, Yoganathan
Published in Molecules (Basel, Switzerland) (23.12.2022)
Published in Molecules (Basel, Switzerland) (23.12.2022)
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Untargeted metabolomics analysis of non-volatile metabolites and dynamic changes of antioxidant capacity in Douchi with edible mushroom by-products
Rong, Pei-Xiu, He, Xiao-Qin, Ayyash, Mutamed, Liu, Yi, Wu, Ding-Tao, Geng, Fang, Li, Hua-Bin, Ng, Siew Bee, Liu, Hong-Yan, Gan, Ren-You
Published in Food chemistry (15.01.2024)
Published in Food chemistry (15.01.2024)
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Fungal Endophytes: A Promising Frontier for Discovery of Novel Bioactive Compounds
Gakuubi, Martin Muthee, Munusamy, Madhaiyan, Liang, Zhao-Xun, Ng, Siew Bee
Published in Journal of fungi (Basel) (22.09.2021)
Published in Journal of fungi (Basel) (22.09.2021)
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In-Silico Identified New Natural Sortase A Inhibitors Disrupt S. aureus Biofilm Formation
Thappeta, Kishore Reddy Venkata, Zhao, Li Na, Nge, Choy Eng, Crasta, Sharon, Leong, Chung Yan, Ng, Veronica, Kanagasundaram, Yoganathan, Fan, Hao, Ng, Siew Bee
Published in International journal of molecular sciences (14.11.2020)
Published in International journal of molecular sciences (14.11.2020)
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Enhancing the Discovery of Bioactive Secondary Metabolites From Fungal Endophytes Using Chemical Elicitation and Variation of Fermentation Media
Gakuubi, Martin Muthee, Ching, Kuan Chieh, Munusamy, Madhaiyan, Wibowo, Mario, Liang, Zhao-Xun, Kanagasundaram, Yoganathan, Ng, Siew Bee
Published in Frontiers in microbiology (06.06.2022)
Published in Frontiers in microbiology (06.06.2022)
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Diversity and Biosynthetic Potential of Fungi Isolated from St. John's Island, Singapore
Munusamy, Madhaiyan, Tan, Kenneth, Nge, Choy Eng, Gakuubi, Martin Muthee, Crasta, Sharon, Kanagasundaram, Yoganathan, Ng, Siew Bee
Published in International journal of molecular sciences (05.01.2023)
Published in International journal of molecular sciences (05.01.2023)
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CRISPR/Cas9 RNP-assisted validation of palmarumycin biosynthetic gene cluster in Lophiotrema sp. F6932
Gakuubi, Martin Muthee, Ching, Kuan Chieh, Munusamy, Madhaiyan, Wibowo, Mario, Lim, Chun Teck, Ma, Guang-Lei, Liang, Zhao-Xun, Kanagasundaram, Yoganathan, Ng, Siew Bee
Published in Frontiers in microbiology (29.09.2022)
Published in Frontiers in microbiology (29.09.2022)
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Discovery of Curcuminoids as Pancreatic Lipase Inhibitors from Medicine-and-Food Homology Plants
He, Xiao-Qin, Zou, Hai-Dan, Liu, Yi, Chen, Xue-Jiao, Atanasov, Atanas G, Wang, Xiao-Li, Xia, Yu, Ng, Siew Bee, Matin, Maima, Wu, Ding-Tao, Liu, Hong-Yan, Gan, Ren-You
Published in Nutrients (01.08.2024)
Published in Nutrients (01.08.2024)
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Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723
Sinha, Swati, Nge, Choy-Eng, Leong, Chung Yan, Ng, Veronica, Crasta, Sharon, Alfatah, Mohammad, Goh, Falicia, Low, Kia-Ngee, Zhang, Huibin, Arumugam, Prakash, Lezhava, Alexander, Chen, Swaine L, Kanagasundaram, Yoganathan, Ng, Siew Bee, Eisenhaber, Frank, Eisenhaber, Birgit
Published in BMC genomics (14.05.2019)
Published in BMC genomics (14.05.2019)
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Application of Cas12j for Streptomyces Editing
Tan, Lee Ling, Heng, Elena, Leong, Chung Yan, Ng, Veronica, Yang, Lay Kien, Seow, Deborah Chwee San, Koduru, Lokanand, Kanagasundaram, Yoganathan, Ng, Siew Bee, Peh, Guangrong, Lim, Yee Hwee, Wong, Fong Tian
Published in Biomolecules (Basel, Switzerland) (16.04.2024)
Published in Biomolecules (Basel, Switzerland) (16.04.2024)
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Tandem mass spectral metabolic profiling of 54 actinobacterial strains and their 459 mutants
Tay, Dillon W. P., Tan, Lee Ling, Heng, Elena, Zulkarnain, Nadiah, Chin, Elaine Jinfeng, Tan, Zann Yi Qi, Leong, Chung Yan, Ng, Veronica Wee Pin, Yang, Lay Kien, Seow, Deborah C. S., Kanagasundaram, Yoganathan, Ng, Siew Bee, Lim, Yee Hwee, Wong, Fong Tian
Published in Scientific data (07.09.2024)
Published in Scientific data (07.09.2024)
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Chemical elicitation as an avenue for discovery of bioactive compounds from fungal endophytes
Munusamy, Madhaiyan, Ching, Kuan Chieh, Yang, Lay Kien, Crasta, Sharon, Gakuubi, Martin Muthee, Chee, Zhao Yan, Wibowo, Mario, Leong, Chung Yan, Kanagasundaram, Yoganathan, Ng, Siew Bee
Published in Frontiers in chemistry (23.11.2022)
Published in Frontiers in chemistry (23.11.2022)
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Identification and engineering of 32 membered antifungal macrolactone notonesomycins
Goh, Falicia, Zhang, Mingzi M, Lim, Tian Ru, Low, Kia Ngee, Nge, Choy Eng, Heng, Elena, Yeo, Wan Lin, Sirota, Fernanda L, Crasta, Sharon, Tan, Zann, Ng, Veronica, Leong, Chung Yan, Zhang, Huibin, Lezhava, Alexander, Chen, Swaine L, Hoon, Shawn S, Eisenhaber, Frank, Eisenhaber, Birgit, Kanagasundaram, Yoganathan, Wong, Fong T, Ng, Siew Bee
Published in Microbial cell factories (19.03.2020)
Published in Microbial cell factories (19.03.2020)
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Cost-effective hybrid long-short read assembly delineates alternative GC-rich Streptomyces hosts for natural product discovery
Heng, Elena, Tan, Lee Ling, Tay, Dillon W.P., Lim, Yee Hwee, Yang, Lay-Kien, Seow, Deborah C.S., Leong, Chung Yan, Ng, Veronica, Ng, Siew Bee, Kanagasundaram, Yoganathan, Wong, Fong Tian, Koduru, Lokanand
Published in Synthetic and systems biotechnology (01.06.2023)
Published in Synthetic and systems biotechnology (01.06.2023)
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Exploring a general multi-pronged activation strategy for natural product discovery in Actinomycetes
Tay, Dillon W. P., Tan, Lee Ling, Heng, Elena, Zulkarnain, Nadiah, Ching, Kuan Chieh, Wibowo, Mario, Chin, Elaine Jinfeng, Tan, Zann Yi Qi, Leong, Chung Yan, Ng, Veronica Wee Pin, Yang, Lay Kien, Seow, Deborah C. S., Lim, Yi Wee, Koh, Winston, Koduru, Lokanand, Kanagasundaram, Yoganathan, Ng, Siew Bee, Lim, Yee Hwee, Wong, Fong Tian
Published in Communications biology (06.01.2024)
Published in Communications biology (06.01.2024)
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Interaction of kendomycin and semi-synthetic analogues with the anti-apoptotic protein Bcl-xl
Janssen, Christian O., Lim, Stephanie, Lo, Ee Peng, Wan, Kah Fei, Yu, Victor C., Lee, May Ann, Ng, Siew Bee, Everett, Martin J., Buss, Antony D., Lane, David P., Boyce, Rustum S.
Published in Bioorganic & medicinal chemistry (01.11.2008)
Published in Bioorganic & medicinal chemistry (01.11.2008)
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