A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch
Amacher, Jeanine F, Zhong, Fangfang, Lisi, George P, Zhu, Michael Q, Alden, Stephanie L, Hoke, Kevin R, Madden, Dean R, Pletneva, Ekaterina V
Published in Journal of the American Chemical Society (08.07.2015)
Published in Journal of the American Chemical Society (08.07.2015)
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Journal Article
Domain Analysis and Motif Matcher (DAMM): A Program to Predict Selectivity Determinants in Monosiga brevicollis PDZ Domains Using Human PDZ Data
Wofford, Haley A., Myers-Dean, Josh, Vogel, Brandon A., Alamo, Kevin Alexander Estrada, Longshore-Neate, Frederick A., Jagodzinski, Filip, Amacher, Jeanine F.
Published in Molecules (Basel, Switzerland) (05.10.2021)
Published in Molecules (Basel, Switzerland) (05.10.2021)
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Journal Article
Specificity in PDZ-peptide interaction networks: Computational analysis and review
Amacher, Jeanine F., Brooks, Lionel, Hampton, Thomas H., Madden, Dean R.
Published in Journal of structural biology. X (01.01.2020)
Published in Journal of structural biology. X (01.01.2020)
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Journal Article
Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses
Amacher, Jeanine F., Cushing, Patrick R., Brooks, Lionel, Boisguerin, Prisca, Madden, Dean R.
Published in Structure (London) (07.01.2014)
Published in Structure (London) (07.01.2014)
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Journal Article
Chemically modified peptide scaffolds target the CFTR-associated ligand PDZ domain
Amacher, Jeanine F, Zhao, Ruizhi, Spaller, Mark R, Madden, Dean R
Published in PloS one (19.08.2014)
Published in PloS one (19.08.2014)
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Journal Article
Sortases: structure, mechanism, and implications for protein engineering
Amacher, Jeanine F., Antos, John M.
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.07.2024)
Published in Trends in biochemical sciences (Amsterdam. Regular ed.) (01.07.2024)
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Journal Article
An Idea to Explore: Engaging High School Students in Structure-Function Studies of Bacterial Sortase Enzymes and Inhibitors -- A Comprehensive Computational Experimental Pipeline
Godse, Shivani, Sapar, Tanvi, Amacher, Jeanine F
Published in Biochemistry and molecular biology education (01.11.2023)
Published in Biochemistry and molecular biology education (01.11.2023)
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Journal Article
Saturation mutagenesis of a predicted ancestral Syk‐family kinase
Hobbs, Helen T., Shah, Neel H., Shoemaker, Sophie R., Amacher, Jeanine F., Marqusee, Susan, Kuriyan, John
Published in Protein science (01.10.2022)
Published in Protein science (01.10.2022)
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Journal Article
Intracellular Delivery of Peptidyl Ligands by Reversible Cyclization: Discovery of a PDZ Domain Inhibitor that Rescues CFTR Activity
Qian, Ziqing, Xu, Xiaohua, Amacher, Jeanine F., Madden, Dean R., Cormet-Boyaka, Estelle, Pei, Dehua
Published in Angewandte Chemie (International ed.) (11.05.2015)
Published in Angewandte Chemie (International ed.) (11.05.2015)
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Journal Article
MotifAnalyzer‐PDZ: A computational program to investigate the evolution of PDZ‐binding target specificity
Valgardson, Jordan, Cosbey, Robin, Houser, Paul, Rupp, Milo, Van Bronkhorst, Raiden, Lee, Michael, Jagodzinski, Filip, Amacher, Jeanine F.
Published in Protein science (01.12.2019)
Published in Protein science (01.12.2019)
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Journal Article
Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes
Gao, Melody, Johnson, D. Alex, Piper, Isabel M., Kodama, Hanna M., Svendsen, Justin E., Tahti, Elise, Longshore‐Neate, Frederick, Vogel, Brandon, Antos, John M., Amacher, Jeanine F.
Published in Protein science (01.03.2022)
Published in Protein science (01.03.2022)
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Journal Article
Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition
Johnson, D. Alex, Piper, Isabel M., Vogel, Brandon A., Jackson, Sophie N., Svendsen, Justin E., Kodama, Hanna M., Lee, Darren E., Lindblom, Katy M., McCarty, James, Antos, John M., Amacher, Jeanine F.
Published in The Journal of biological chemistry (01.10.2022)
Published in The Journal of biological chemistry (01.10.2022)
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Journal Article
Additive energetic contributions of multiple peptide positions determine the relative promiscuity of viral and human sequences for PDZ domain targets
Tahti, Elise F., Blount, Jadon M., Jackson, Sophie N., Gao, Melody, Gill, Nicholas P., Smith, Sarah N., Pederson, Nick J., Rumph, Simone N., Struyvenberg, Sarah A., Mackley, Iain G. P., Madden, Dean R., Amacher, Jeanine F.
Published in Protein science (01.04.2023)
Published in Protein science (01.04.2023)
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Journal Article
Phosphorylation control of the ubiquitin ligase Cbl is conserved in choanoflagellates
Amacher, Jeanine F., Hobbs, Helen T., Cantor, Aaron C., Shah, Lochan, Rivero, Marco‐Jose, Mulchand, Sarah A., Kuriyan, John
Published in Protein science (01.05.2018)
Published in Protein science (01.05.2018)
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Journal Article
Stereochemical determinants of C-terminal specificity in PDZ peptide-binding domains: a novel contribution of the carboxylate-binding loop
Amacher, Jeanine F, Cushing, Patrick R, Bahl, Christopher D, Beck, Tobias, Madden, Dean R
Published in The Journal of biological chemistry (15.02.2013)
Published in The Journal of biological chemistry (15.02.2013)
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Journal Article
A unique binding mode of P1' Leu-containing target sequences for Streptococcus pyogenes sortase A results in alternative cleavage
Vogel, Brandon A, Blount, Jadon M, Kodama, Hanna M, Goodwin-Rice, Noah J, Andaluz, Devin J, Jackson, Sophie N, Antos, John M, Amacher, Jeanine F
Published in RSC chemical biology (03.01.2024)
Published in RSC chemical biology (03.01.2024)
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Journal Article
Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor
Amacher, Jeanine F., Cushing, Patrick R., Weiner, Joshua A., Madden, Dean R.
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.05.2011)
Published in Acta crystallographica. Section F, Structural biology and crystallization communications (01.05.2011)
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Journal Article
Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition
Johnson, D. Alex, Piper, Isabel M., Vogel, Brandon A., Jackson, Sophie N., Svendsen, Justin E., Kodama, Hanna M., Lee, Darren E., Lindblom, Katy M., McCarty, James, Antos, John M., Amacher, Jeanine F.
Published in The Journal of biological chemistry (01.10.2022)
Published in The Journal of biological chemistry (01.10.2022)
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Journal Article